Effects of Mechanical Compression on Chondrogenesis of Human Synovium-Derived Mesenchymal Stem Cells in Agarose Hydrogel

• Published in: Frontiers in bioengineering and biotechnology Vol. 9; p. 697281
• Main Authors: Ge, Yuxiang, Li, Yixuan, Wang, Zixu, Li, Lan, Teng, Huajian, Jiang, Qing
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 19.07.2021
• Subjects: Bioengineering and Biotechnology; cartilage repair; chondrocytes; chondrogenesis; mechanical compression; SMSCs

Mechanical compression is a double-edged sword for cartilage remodeling, and the effect of mechanical compression on chondrogenic differentiation still remains elusive to date. Herein, we investigate the effect of mechanical dynamic compression on the chondrogenic differentiation of human synovium-d...