Segregation Analysis of Genotyped and Family-Phased, Long Range MHC Classical Class I and Class II Haplotypes in 5 Families With Type 1 Diabetes Proband in the United Arab Emirates

• Published in: Frontiers in genetics Vol. 12; p. 670844
• Main Authors: Tay, Guan K., Al Naqbi, Halima, Mawart, Aurélie, Baalfaqih, Zahrah, Almaazmi, Anoud, Deeb, Asma, Alsafar, Habiba
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 30.06.2021
• Subjects: Arab; DR3/DR4 haplotypes; Genetics; major histocompatibility complex; type 1 diabetes; UAE

The classical Human Leucocyte Antigen (HLA) class II haplotypes of the Major Histocompatibility Complex (MHC) that are associated with type 1 diabetes (T1D) were identified in five families from the United Arab Emirates (UAE). Segregation analyses were performed on these 5 families with the disease,...