Wenshenyang recipe treats infertility through hormonal regulation and inflammatory responses revealed by transcriptome analysis and network pharmacology

• Published in: Frontiers in pharmacology Vol. 13; p. 917544
• Main Authors: Xie, Lan, Zhao, Shuai, Zhang, Xiaoling, Huang, Wenting, Qiao, Liansheng, Zhan, Delin, Ma, Chengmei, Gong, Wei, Dang, Honglei, Lu, Hua
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 08.08.2022
• Subjects: GO enrichment analysis; infertility; network pharmacology; pathway enrichment analysis; Pharmacology; transcriptome analysis; wenshenyang recipe

The Wenshenyang recipe (WSYR) has the effect of treating infertility, but the mechanisms underlying this activity have not been fully elucidated. In this study, network pharmacology and RNA sequencing were combined, with database-based “dry” experiments and transcriptome analysis-based “wet” experim...