The effects of an oral preparation containing hyaluronic acid (Oralvisc®) on obese knee osteoarthritis patients determined by pain, function, bradykinin, leptin, inflammatory cytokines, and heavy water analyses - Nelson, F. R.; Zvirbulis, R. A.; Zonca, B.; Li, K. W.; Turner, S. M.; Pasierb, M.; Wilton, P.; Martinez-Puig, D.; Wu, W. (Rheumatology international, 2015)
Keywords: Adjuvants, Immunologic - administration & dosage; Adjuvants, Immunologic - therapeutic use; Administration, Oral; Aged; Bradykinin - blood; Cytokines - blood; Deuterium Oxide - analysis; Double-Blind Method; Female; Humans; Hyaluronic Acid - administration & dosage; Hyaluronic Acid - therapeutic use; Knee Joint - physiopathology; Leptin - blood; Male; Medicine; Medicine & Public Health; Middle Aged; Obesity - blood; Obesity - complications; Obesity - physiopathology; Original Article; Osteoarthritis, Knee - blood; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - drug therapy; Osteoarthritis, Knee - physiopathology; Pain - blood; Pain - complications; Pain - drug therapy; Pain - physiopathology; Pain Measurement; Rheumatology; Synovial Fluid; Treatment Outcome; Knee; Clinical Outcomes Research; Function; Pain; Cytokines; Osteoarthritis