Development of a Hyperosmotic Stress Inducible Gene Expression System by Engineering the MtrA/MtrB-Dependent NCgl1418 Promoter in Corynebacterium glutamicum

• Published in: Frontiers in microbiology Vol. 12; p. 718511
• Main Authors: Huang, Jingwen, Chen, Jiuzhou, Wang, Yu, Shi, Tuo, Ni, Xiaomeng, Pu, Wei, Liu, Jiao, Zhou, Yingyu, Cai, Ningyun, Han, Shuangyan, Zheng, Ping, Sun, Jibin
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 21.07.2021
• Subjects: Corynebacterium glutamicum; fluorescence activated cell sorting; hyperosmotic stress; inducible promoter; lysine; Microbiology; MtrA

Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Precise regulation of gene expression is crucial for metabolic balance and enhancing production of target molecules. Auto-inducible promoters, which can be activated without expensive inducers,...