HER2 expression in urothelial carcinoma, a systematic literature review

• Published in: Frontiers in oncology Vol. 12; p. 1011885
• Main Authors: Scherrer, Emilie, Kang, Ashley, Bloudek, Lisa M., Koshkin, Vadim S.
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 21.10.2022
• Subjects: ErbB2; HER2; Oncology; systematic literature search; targeted therapy; urothelial carcinoma

Background Urothelial carcinoma (UC) is a common malignancy with significant associated mortality. Recent clinical trials suggest an emerging role for HER2-targeted therapy. Testing for HER2 expression in UC is not part of current routine clinical practice. In consequence, the prevalence of HER2 exp...