Hesperidin promotes gastric motility in rats with functional dyspepsia by regulating Drp1-mediated ICC mitophagy

• Published in: Frontiers in pharmacology Vol. 13; p. 945624
• Main Authors: Jia, Qingling, Li, Li, Wang, Xiangxiang, Wang, Yujiao, Jiang, Kailin, Yang, Keming, Cong, Jun, Cai, Gan, Ling, Jianghong
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 12.08.2022
• Subjects: Drp1; functional dyspepsia; hesperidin; mdivi-1; mitophagy; Pharmacology

Hesperidin is one of the main active ingredients of Citrus aurantium L. (Rutaceae) and tangerine peel, which have anti-inflammatory and antioxidant effects. In previous study, we found that gastric motility disorder in functional dyspepsia (FD) rats accompanied by excessive autophagy/mitochondrial s...