Influenza Vaccine Effectiveness in Households With Children During the 2012-2013 Season: Assessments of Prior Vaccination and Serologic Susceptibility

• Published in: The Journal of infectious diseases Vol. 211; no. 10; pp. 1519 - 1528
• Main Authors: Ohmit, Suzanne E., Petrie, Joshua G., Malosh, Ryan E., Fry, Alicia M., Thompson, Mark G., Monto, Arnold S.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 15.05.2015
• Series: Editor's choice
• Subjects: Adolescent; Adult; Antibodies, Viral - blood; Child; Family Characteristics; Female; Hemagglutination Inhibition Tests; Humans; Infant; Influenza Vaccines - administration & dosage; Influenza Vaccines - immunology; Influenza, Human - immunology; Influenza, Human - prevention & control; Major and Brief Reports; Male; Middle Aged; Treatment Outcome; VIRUSES; Young Adult; influenza; vaccine effectiveness; households with children; serologic susceptibility
• ISSN: 0022-1899; 1537-6613; 1537-6613
• DOI: 10.1093/infdis/jiu650

Background. There are recognized needs to identify determinants of influenza vaccine effectiveness (VE), including the effect of repeated annual vaccination. Methods. We recruited 321 households with 1426 members, including 833 children, and followed them during the 2012-2013 influenza season; speci...