Suppression of Akt-HIF-1α signaling axis by diacetyl atractylodiol inhibits hypoxia-induced angiogenesis - Choi, Sik-Won; Lee, Kwang-Sik; Lee, Jin Hwan; Kang, Hyeon Jung; Lee, Mi Ja; Kim, Hyun Young; Park, Kie-In; Kim, Sun-Lim; Shin, Hye Kyoung; Seo, Woo Duck (BMB reports, 2016)
Keywords: Atractylodes - chemistry; Atractylodes - metabolism; Blotting, Western; Chorioallantoic Membrane - drug effects; Chorioallantoic Membrane - physiology; Cobalt - toxicity; Down-Regulation - drug effects; Enediynes - pharmacology; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit - genetics; Hypoxia-Inducible Factor 1, alpha Subunit - metabolism; Neovascularization, Physiologic - drug effects; Phosphorylation - drug effects; Proto-Oncogene Proteins c-akt - metabolism; Real-Time Polymerase Chain Reaction; Signal Transduction - drug effects; Vascular Endothelial Growth Factor A - genetics; Vascular Endothelial Growth Factor A - metabolism; 화학