Biophysical Tools and Concepts Enable Understanding of Asexual Blood Stage Malaria

• Published in: Frontiers in cellular and infection microbiology Vol. 12; p. 908241
• Main Authors: Introini, Viola, Govendir, Matt A., Rayner, Julian C., Cicuta, Pietro, Bernabeu, Maria
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 31.05.2022
• Subjects: biophysics; Cellular and Infection Microbiology; cytoadhesion; imaging; malaria; microfluidics; Plasmodium

Forces and mechanical properties of cells and tissues set constraints on biological functions, and are key determinants of human physiology. Changes in cell mechanics may arise from disease, or directly contribute to pathogenesis. Malaria gives many striking examples. Plasmodium parasites, the causa...