Changes of Serum IgG Glycosylation Patterns in Primary Biliary Cholangitis Patients

• Published in: Frontiers in immunology Vol. 12; p. 669137
• Main Authors: Zeng, Xiaoli, Li, Siting, Tang, Shiyi, Li, Xi, Zhang, Guoyuan, Li, Mengtao, Zeng, Xiaofeng, Hu, Chaojun
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 25.06.2021
• Subjects: autoantibody; glycosylation; immunoglobulin G; Immunology; lectin microarray; primary biliary cholangitis

Primary biliary cholangitis (PBC) is an autoimmune cholestatic liver disease whose diagnosis is based significantly on autoantibody detection. This study aims to investigate the glycosylation profile of serum IgG in PBC patients using high-throughput lectin microarrays technology.ObjectivePrimary bi...