Advances in immunotherapy for glioblastoma multiforme

• Published in: Frontiers in immunology Vol. 13; p. 944452
• Main Authors: Mahmoud, Ahmad Bakur, Ajina, Reham, Aref, Sarah, Darwish, Manar, Alsayb, May, Taher, Mustafa, AlSharif, Shaker A., Hashem, Anwar M., Alkayyal, Almohanad A.
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 12.10.2022
• Subjects: CAR-T cells; checkpoint inhibitors; glioblastoma multiforme; glioma; Immunology; immunotherapy; oncolytic virotherapy

Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor of the central nervous system and has a very poor prognosis. The current standard of care for patients with GBM involves surgical resection, radiotherapy, and chemotherapy. Unfortunately, conventional therapies hav...