Potential Role of S-Palmitoylation in Cancer Stem Cells of Lung Adenocarcinoma

• Published in: Frontiers in cell and developmental biology Vol. 9; p. 734897
• Main Authors: Zhang, Yitong, Li, Fenglan, Fu, Kexin, Liu, Xiqing, Lien, I-Chia, Li, Hui
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 21.09.2021
• Subjects: cancer stem cell; Cell and Developmental Biology; INCENP; lung adenocarcinoma; mRNAsi; S-palmitoylation; ZDHHC5

S-palmitoylation, catalyzed by a family of 23 zinc finger Asp-His-His-Cys (DHHC) domain-containing (ZDHHC) protein acyltransferases localized on the cell membrane. However, stemness genes modulated by ZDHHCs in lung adenocarcinoma (LUAD) remain to be defined. Previously, we have constructed a networ...