Regulation of glucose transport by hypoxia

• Published in: American journal of kidney diseases Vol. 34; no. 1; p. 189
• Main Authors: Zhang, J Z, Behrooz, A, Ismail-Beigi, F
• Format: Journal Article
• Language: English
• Published: United States 01.07.1999
• Subjects: Animals; Biological Transport, Active; Cell Hypoxia - physiology; Glucose - metabolism; Glucose Transporter Type 1; Glucose Transporter Type 3; Glucose Transporter Type 4; Humans; Monosaccharide Transport Proteins - genetics; Monosaccharide Transport Proteins - physiology; Muscle Proteins; Nerve Tissue Proteins; Transcription, Genetic

Transport of glucose into most mammalian cells and tissues is rate-controlling for its metabolism. Glucose transport is acutely stimulated by hypoxic conditions, and the response is mediated by enhanced function of the facilitative glucose transporters (Glut), Glut1, Glut3, and Glut4. The expression...