3-Phenyllactic acid generated in medicinal plant extracts fermented with plant-derived lactic acid bacteria inhibits the biofilm synthesis of Aggregatibacter actinomycetemcomitans

• Published in: Frontiers in microbiology Vol. 13; p. 991144
• Main Authors: Shakya, Shrijana, Danshiitsoodol, Narandalai, Noda, Masafumi, Inoue, Yusuke, Sugiyama, Masanori
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 23.09.2022
• Subjects: 3-phenyllactic acid; Aggregatibacter actinomycetemcomitans; biofilm; fermentation; lactic acid bacteria; Microbiology; Paeonia Radix Alba

In the present study, the effect of PLA on a periodontic pathogen, Aggregatibacter actinomycetemcomitans ( A. actinomycetemcomitans ), the biofilm, and virulence-related genes was investigated. We confirmed that two lactic acid bacteria (LAB) strains isolated from plant sources, Lactiplantibacillus...