Fibroblast growth factor 21 in chronic kidney disease

• Published in: Journal of nephrology Vol. 32; no. 3; pp. 365 - 377
• Main Authors: Suassuna, Paulo Giovanni de Albuquerque, de Paula, Rogério Baumgratz, Sanders-Pinheiro, Hélady, Moe, Orson W., Hu, Ming-Chang
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2019
• Subjects: Medicine; Medicine & Public Health; Nephrology; Review; Urology; Diabetic nephropathy; Chronic kidney disease; FGF21

Fibroblast growth factor 21 (FGF21) is a member of the endocrine FGF family that acts as a metabolic regulator of both glucose and lipid metabolism. Similar to fibroblast growth factor 23 (FGF23), serum FGF21 levels rise progressively with the loss of renal function, reaching 20 times normal values...