Dual-stimuli-responsive polymer-coated mesoporous silica nanoparticles used for controlled drug delivery

• Published in: Journal of applied polymer science Vol. 132; no. 32
• Main Authors: Yang, Mei-Yan, Tan, Lei, Wu, Hai-Xia, Liu, Chuan-Jun, Zhuo, Ren-Xi
• Format: Journal Article
• Language: English
• Published: Hoboken Blackwell Publishing Ltd 20.08.2015; Wiley Subscription Services, Inc
• Subjects: biomaterials; drug-delivery systems; Materials science; nanoparticles; nanowires and nanocrystals; Polymers; stimuli-sensitive polymers

ABSTRACT In this article, a temperature‐ and pH‐responsive delivery system based on block‐copolymer‐capped mesoporous silica nanoparticles (MSNs) is presented. A poly[2‐(diethylamino)ethyl methacrylate)] (PDEAEMA)‐b‐poly(N‐isopropyl acrylamide) (PNIPAM) shell on MSNs was obtained through the surface...