Neurodevelopmental subtypes of bipolar disorder are related to cortical folding patterns: An international multicenter study

• Published in: Bipolar disorders Vol. 20; no. 8; pp. 721 - 732
• Main Authors: Sarrazin, Samuel, Cachia, Arnaud, Hozer, Franz, McDonald, Colm, Emsell, Louise, Cannon, Dara M, Wessa, Michele, Linke, Julia, Versace, Amelia, Hamdani, Nora, D'Albis, Marc‐Antoine, Delavest, Marine, Phillips, Mary L., Brambilla, Paolo, Bellani, Marcella, Polosan, Mircea, Favre, Pauline, Leboyer, Marion, Mangin, Jean‐François, Houenou, Josselin
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.12.2018; Wiley
• Subjects: Adult; Bipolar Disorder; Bipolar Disorder - diagnostic imaging; Bipolar Disorder - pathology; Brain; Brain - diagnostic imaging; Brain - pathology; Brain Mapping; Case-Control Studies; Cortex (parietal); early‐onset; Female; Functional Laterality; Handedness; Humans; Life Sciences; Magnetic Resonance Imaging; Magnetic Resonance Imaging - methods; Male; neurodevelopment; Neurodevelopmental disorders; Neuroimaging; NMR; Nuclear magnetic resonance; Parietal Lobe; Parietal Lobe - diagnostic imaging; Parietal Lobe - pathology; Phenotypes; Phenotypic variations; Prefrontal Cortex; Prefrontal Cortex - diagnostic imaging; Prefrontal Cortex - pathology; Psychosis; Psychotic Disorders; Psychotic Disorders - diagnostic imaging; Psychotic Disorders - pathology; sulcation; sulcation; bipolar disorder; magnetic resonance imaging; early-onset; neurodevelopment; psychosis; inferior frontal gyrus; inhibitory control; anterior cingulate cortex

Objectives Brain sulcation is an indirect marker of neurodevelopmental processes. Studies of the cortical sulcation in bipolar disorder have yielded mixed results, probably due to high variability in clinical phenotype. We investigated whole‐brain cortical sulcation in a large sample of selected pat...