Association between prescription drugs and all‐cause mortality risk in the UK population

• Published in: Aging cell Vol. 23; no. 12; pp. e14334 - n/a
• Main Authors: Morin, Jonas, Rolland, Yves, Bischoff‐Ferrari, Heike A., Ocampo, Alejandro, Perez, Kevin
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.12.2024; Wiley Open Access; John Wiley and Sons Inc
• Subjects: 17β-Estradiol; Adult; Aged; aging; all‐cause mortality; Atorvastatin; biobank; Chronic obstructive pulmonary disease; Female; Humans; Life Sciences; Life span; lifespan; Male; medications; Metformin; Middle Aged; Mortality; Mortality - trends; mortality risk; Prescription drugs; Prescription Drugs - therapeutic use; Rapamycin; repurposing; United Kingdom - epidemiology; Womens health; United Kingdom; United Kingdom > UK; prescription drugs; lifespan; medications; all‐cause mortality; repurposing; aging; biobank; mortality risk

Although most drugs currently approved are meant to treat specific diseases or symptoms, it has been hypothesized that some might bear a beneficial effect on lifespan in healthy older individuals, outside of their specific disease indication. Such drugs include, among others, metformin, SGLT2 inhibi...