Solution structure and behaviour of the Arabidopsis thaliana HYL1 protein

• Published in: Biochimica et biophysica acta. General subjects Vol. 1867; no. 8; p. 130376
• Main Authors: Wieczorek, Przemysław, Jarmołowski, Artur, Szweykowska-Kulińska, Zofia, Kozak, Maciej, Taube, Michał
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2023
• Subjects: amino acid sequences; Arabidopsis - genetics; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; biogenesis; Cell Cycle Proteins - metabolism; dimerization; excision; genes; HYL1; microRNA; MicroRNAs - genetics; miRNA biogenesis; phosphorylation; Protein dimerization; Protein disorder; Protein structure; ribonucleases; RNA-Binding Proteins - metabolism; Scattering, Small Angle; X-radiation; X-Ray Diffraction; Protein dimerization; miRNA biogenesis; Protein disorder; HYL1; Protein structure

In plants, microRNA biogenesis involves the complex assembly of molecular processes that are mostly governed by three proteins: RNase III protein DCL1 and two RNA binding proteins, SERRATE and HYL1. HYL1 protein is a double stranded RNA binding protein that is needed for the precise excision of miRN...