Metabolic fingerprinting reveals extensive consequences of GLS hyperactivity - Rumping, Lynne; Pras-Raves, Mia L.; Gerrits, Johan; Tang, Yuen Fung; Willemsen, Marcel A.; Houwen, Roderick H.J.; van Haaften, Gijs; van Hasselt, Peter M.; Verhoeven-Duif, Nanda M.; Jans, Judith J.M. (Biochimica et biophysica acta. General subjects, 2020)
Keywords: asparagine; aspartic acid; carcinogenesis; catalytic activity; citrates; DI-HRMS; enzyme activity; gamma-aminobutyric acid; Glutamate metabolism; glutamic acid; glutaminase; Glutaminase activity; glutamine; glutathione; mass spectrometry; metabolic diseases; Metabolic profiling; metabolism; metabolites; metabolome; metabolomics; nucleotides; ornithine; pathophysiology; proline; thymine; transamination; tricarboxylic acid cycle; Untargeted metabolomics; Metabolic profiling; Glutaminase activity; Glutamate metabolism; DI-HRMS; Untargeted metabolomics