Identification of pelvic organ prolapse risk susceptibility gene SNP locus in Xinjiang women

• Published in: International Urogynecology Journal Vol. 31; no. 1; pp. 123 - 130
• Main Authors: Abulaizi, Aibibuhan·, Abula, Abudoureyimu·, Ababaikeli, Gulina·, Wan, Xiaohui, Du, Rong, Zhakeer, Adilai
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.01.2020; Springer Nature B.V
• Subjects: Adult; Case-Control Studies; China; Estrogen Receptor alpha - genetics; Extracellular Matrix Proteins - genetics; Female; Genes; Genetic Predisposition to Disease; Genotype & phenotype; Gynecology; Health risk assessment; Humans; Medicine; Medicine & Public Health; Middle Aged; Original Article; Pelvic organ prolapse; Pelvic Organ Prolapse - genetics; Polymorphism, Single Nucleotide; Transcription Factors - genetics; Urology; China; Pelvic organ prolapse; Single-nucleotide polymorphism; Susceptibility genes; Risk factor

Introduction and hypothesis Susceptibility genes play an important role and have regional specificity in the occurrence of pelvic organ prolapse (POP). This study aims to identify POP susceptibility genes and their loci in ethnic minorities with different genetic backgrounds from Xinjiang in China,...