The origins and dynamic changes of C3- and S100A10-positive reactive astrocytes after spinal cord injury

• Published in: Frontiers in cellular neuroscience Vol. 17; p. 1276506
• Main Authors: Zhao, Qing, Ren, Yi-Long, Zhu, Yan-Jing, Huang, Rui-Qi, Zhu, Rong-Rong, Cheng, Li-Ming, Xie, Ning
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 22.12.2023; Frontiers Media S.A
• Subjects: Animal models; Antibodies; Astrocytes; C3- and S100A10-positive reactive astrocytes; Calcium-binding protein; Contusions; distribution; dynamic changes; Ependymal cells; Females; Genes; Genetic transformation; Hypoxia; Laboratory animals; origins; Penicillin; Phenotypes; Proteins; Ribonucleic acid; RNA; S100 protein; Spinal cord injuries; spinal cord injury; Toxicity; Transgenic animals; Transgenic mice; China; spinal cord injury; C3- and S100A10-positive reactive astrocytes; origins; distribution; dynamic changes

Accaumulating studies focus on the effects of C3-positive A1-like phenotypes and S100A10-positive A2-like phenotypes of reactive astrocytes on spinal cord injury (SCI), however the origins and dynamic changes of C3- and S100A10-positive reactive astrocytes after SCI remain poorly understood. Through...