The use of prostate specific antigen density to enhance the predictive value of intermediate levels of serum prostate specific antigen

• Published in: The Journal of urology Vol. 147; no. 3 Pt 2; p. 817
• Main Authors: Benson, M C, Whang, I S, Olsson, C A, McMahon, D J, Cooner, W H
• Format: Journal Article
• Language: English
• Published: United States 01.03.1992
• Subjects: Aged; Aged, 80 and over; Antigens, Neoplasm - blood; Biomarkers, Tumor - blood; Densitometry; Humans; Male; Middle Aged; Predictive Value of Tests; Prostate - diagnostic imaging; Prostate - pathology; Prostate-Specific Antigen; Ultrasonography

Prostate specific antigen (PSA) is an extremely valuable tumor marker. However, its use in detection is limited by its low positive and negative predictive values. The ability of serum PSA to distinguish between benign and malignant prostatic conditions is particularly poor in the intermediate range...