The emerging mechanisms and functions of microautophagy

• Published in: Nature reviews. Molecular cell biology Vol. 24; no. 3; pp. 186 - 203
• Main Authors: Wang, Liming, Klionsky, Daniel J., Shen, Han-Ming
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.03.2023; Nature Publishing Group
• Subjects: 631/80/39; 631/80/474/1624; Animals; Autophagy; Biochemistry; Biomedical and Life Sciences; Cancer Research; Cell Biology; Cell Communication; Degradation; Developmental Biology; Endosomes; Humans; Life Sciences; Lysosomes; Lysosomes - metabolism; Macroautophagy; Mammalian cells; Mammals; Microautophagy; Molecular modelling; Neurodegenerative diseases; Organelles; Proteins; Regulatory mechanisms (biology); Review Article; Stem Cells; Yeast

‘Autophagy’ refers to an evolutionarily conserved process through which cellular contents, such as damaged organelles and protein aggregates, are delivered to lysosomes for degradation. Different forms of autophagy have been described on the basis of the nature of the cargoes and the means used to d...