Revisiting Astrocytic Roles in Methylmercury Intoxication

• Published in: Molecular neurobiology Vol. 58; no. 9; pp. 4293 - 4308
• Main Authors: Arrifano, Gabriela de Paula, Augusto-Oliveira, Marcus, Souza-Monteiro, José Rogério, Macchi, Barbarella de Matos, Lima, Rafael Rodrigues, Suñol, Cristina, do Nascimento, José Luis Martins, Crespo-Lopez, Maria Elena
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.09.2021; Springer Nature B.V
• Subjects: Astrocytes; Astrocytes - drug effects; Astrocytes - pathology; Biomedical and Life Sciences; Biomedicine; Brain - drug effects; Brain - pathology; Brain injury; Cell Biology; Central nervous system; Dimethylmercury; Glial cells; Heavy metals; Homeostasis; Humans; Intoxication; Memory; Methylmercury Compounds - toxicity; Neurobiology; Neurology; Neuromodulation; Neurons; Neurons - drug effects; Neurons - pathology; Neurosciences; Neurotoxicity; Neurotoxicity Syndromes - pathology; Public health; Roles; Visual discrimination learning; Human; Brain; Pollutant; Astroglia; Metal; Glia; Mercury

Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system pathologies. Most of these neuropathological conditions involve vascular, neurotransmitter recycling, and oxidative balance disruption leading to acc...