Revisiting Astrocytic Roles in Methylmercury Intoxication

Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system pathologies. Most of these neuropathological conditions involve vascular, neurotransmitter recycling, and oxidative balance disruption leading to acc...

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Published inMolecular neurobiology Vol. 58; no. 9; pp. 4293 - 4308
Main Authors Arrifano, Gabriela de Paula, Augusto-Oliveira, Marcus, Souza-Monteiro, José Rogério, Macchi, Barbarella de Matos, Lima, Rafael Rodrigues, Suñol, Cristina, do Nascimento, José Luis Martins, Crespo-Lopez, Maria Elena
Format Journal Article
LanguageEnglish
Published New York Springer US 01.09.2021
Springer Nature B.V
Subjects
Astrocytes
Astrocytes - drug effects
Astrocytes - pathology
Biomedical and Life Sciences
Biomedicine
Brain - drug effects
Brain - pathology
Brain injury
Cell Biology
Central nervous system
Dimethylmercury
Glial cells
Heavy metals
Homeostasis
Humans
Intoxication
Memory
Methylmercury Compounds - toxicity
Neurobiology
Neurology
Neuromodulation
Neurons
Neurons - drug effects
Neurons - pathology
Neurosciences
Neurotoxicity
Neurotoxicity Syndromes - pathology
Public health
Roles
Visual discrimination learning
Human
Brain
Pollutant
Astroglia
Metal
Glia
Mercury
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Abstract Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system pathologies. Most of these neuropathological conditions involve vascular, neurotransmitter recycling, and oxidative balance disruption leading to accelerated decline in fine balance, and learning, memory, and visual processes as main outcomes. Besides neurons, astrocytes are involved in virtually all the brain processes and perform important roles in neurological response following injuries. Due to astrocytes’ strategic functions in brain homeostasis, these cells became the subject of several studies on MeHg intoxication. The most heterogenous glial cells, astrocytes, are composed of plenty of receptors and transporters to dialogue with neurons and other cells and to monitor extracellular environment responding tightly through fluctuation of cytosolic ions. The overall toxicity of MeHg might be determined on the basis of the balance between MeHg-mediated injury to neurons and protective responses from astrocytes. Although the role of neurons in MeHg intoxication is relatively well-established, the role of the astrocytes is only beginning to be understood. In this review, we update the information on astroglial modulation of the MeHg-induced neurotoxicity, providing remarks on their protective and deleterious roles and insights for future studies.
AbstractList Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system pathologies. Most of these neuropathological conditions involve vascular, neurotransmitter recycling, and oxidative balance disruption leading to accelerated decline in fine balance, and learning, memory, and visual processes as main outcomes. Besides neurons, astrocytes are involved in virtually all the brain processes and perform important roles in neurological response following injuries. Due to astrocytes' strategic functions in brain homeostasis, these cells became the subject of several studies on MeHg intoxication. The most heterogenous glial cells, astrocytes, are composed of plenty of receptors and transporters to dialogue with neurons and other cells and to monitor extracellular environment responding tightly through fluctuation of cytosolic ions. The overall toxicity of MeHg might be determined on the basis of the balance between MeHg-mediated injury to neurons and protective responses from astrocytes. Although the role of neurons in MeHg intoxication is relatively well-established, the role of the astrocytes is only beginning to be understood. In this review, we update the information on astroglial modulation of the MeHg-induced neurotoxicity, providing remarks on their protective and deleterious roles and insights for future studies.
Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system pathologies. Most of these neuropathological conditions involve vascular, neurotransmitter recycling, and oxidative balance disruption leading to accelerated decline in fine balance, and learning, memory, and visual processes as main outcomes. Besides neurons, astrocytes are involved in virtually all the brain processes and perform important roles in neurological response following injuries. Due to astrocytes' strategic functions in brain homeostasis, these cells became the subject of several studies on MeHg intoxication. The most heterogenous glial cells, astrocytes, are composed of plenty of receptors and transporters to dialogue with neurons and other cells and to monitor extracellular environment responding tightly through fluctuation of cytosolic ions. The overall toxicity of MeHg might be determined on the basis of the balance between MeHg-mediated injury to neurons and protective responses from astrocytes. Although the role of neurons in MeHg intoxication is relatively well-established, the role of the astrocytes is only beginning to be understood. In this review, we update the information on astroglial modulation of the MeHg-induced neurotoxicity, providing remarks on their protective and deleterious roles and insights for future studies.Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system pathologies. Most of these neuropathological conditions involve vascular, neurotransmitter recycling, and oxidative balance disruption leading to accelerated decline in fine balance, and learning, memory, and visual processes as main outcomes. Besides neurons, astrocytes are involved in virtually all the brain processes and perform important roles in neurological response following injuries. Due to astrocytes' strategic functions in brain homeostasis, these cells became the subject of several studies on MeHg intoxication. The most heterogenous glial cells, astrocytes, are composed of plenty of receptors and transporters to dialogue with neurons and other cells and to monitor extracellular environment responding tightly through fluctuation of cytosolic ions. The overall toxicity of MeHg might be determined on the basis of the balance between MeHg-mediated injury to neurons and protective responses from astrocytes. Although the role of neurons in MeHg intoxication is relatively well-established, the role of the astrocytes is only beginning to be understood. In this review, we update the information on astroglial modulation of the MeHg-induced neurotoxicity, providing remarks on their protective and deleterious roles and insights for future studies.
Author Souza-Monteiro, José Rogério
Lima, Rafael Rodrigues
do Nascimento, José Luis Martins
Crespo-Lopez, Maria Elena
Suñol, Cristina
Augusto-Oliveira, Marcus
Arrifano, Gabriela de Paula
Macchi, Barbarella de Matos
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  surname: Suñol
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  fullname: do Nascimento, José Luis Martins
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  surname: Crespo-Lopez
  fullname: Crespo-Lopez, Maria Elena
  email: maria.elena.crespo.lopez@gmail.com
  organization: Laboratório de Farmacologia Molecular, Instituto de Ciências Biológicas, Universidade Federal do Pará
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Cites_doi 10.1371/journal.pone.0098161
10.1016/j.brainres.2020.147234
10.1016/s0161-813x(01)00015-8
10.1371/journal.pone.0218415
10.1016/j.phrs.2009.02.011
10.1016/j.fct.2018.01.057
10.1007/s11064-019-02881-7
10.1385/BTER:107:3:231
10.1016/j.jtemb.2015.06.008
10.1039/c8mt00297e
10.2131/fts.3.63
10.1002/glia.10019
10.2131/jts.37.1275
10.1016/j.neuro.2004.01.005
10.1523/JNEUROSCI.17-01-00171.1997
10.1016/j.taap.2009.09.022
10.1016/j.lfs.2011.05.019
10.1016/s0197-0186(00)00023-1
10.1093/toxsci/kfr252
10.1182/blood.V83.1.113.113
10.1016/j.etap.2015.06.010
10.1016/s0006-8993(01)02375-7
10.1371/journal.pone.0057898
10.1016/S0169-328X(02)00403-5
10.1080/10408440802004023
10.1016/j.bbrc.2019.09.030
10.1016/s0028-3908(01)00130-7
10.3109/15563650.2013.860986
10.1016/j.neuro.2016.05.018
10.1007/978-3-319-60189-2_13
10.1016/j.tiv.2019.02.013
10.1002/jnr.10066
10.1007/978-1-61779-170-3_17
10.1039/C2TX20010D
10.1016/s0300-483x(01)00415-2
10.1016/j.neuro.2011.01.004
10.1385/BTER:95:1:1
10.1007/s12035-015-9161-y
10.1038/nm.4106
10.1002/glia.23759
10.1016/j.neuro.2018.07.018
10.1016/j.toxlet.2017.12.006
10.1016/j.envint.2006.08.005
10.1289/EHP3904
10.2131/jts.37.749
10.1016/0006-8993(90)91290-w
10.1016/s0161-813x(01)00050-x
10.3389/fnmol.2018.00125
10.1186/s12974-017-0871-0
10.1177/1091581817739428
10.1038/s41598-019-49009-z
10.1096/fj.12-208660
10.1016/0006-2952(94)90527-4
10.2131/jts.38.837
10.1007/s12035-016-0101-2
10.1016/0887-2333(95)00002-p
10.1016/s0006-8993(01)02791-3
10.1289/ehp.0901757
10.1080/10408440600845619
10.1038/nature11748
10.1016/j.neuint.2009.01.015
10.1016/j.envint.2010.08.009
10.1038/nature17623
10.1038/cdd.2015.49
10.1016/j.jtemb.2018.09.004
10.1016/j.taap.2011.05.001
10.2174/1568026013394831
10.1016/s0006-8993(96)00895-5
10.1007/s002040000112
10.1371/journal.pone.0170623
10.1016/j.jchemneu.2008.01.003
10.1016/j.ecoenv.2020.111686
10.1038/s41598-019-50377-9
10.1016/j.cortex.2015.05.017
10.1371/journal.pone.0070163
10.1289/ehp.1104494
10.3109/10915818909009095
10.1152/physrev.00011.2013
10.1155/2018/7878050
10.1002/glia.21153
10.1289/ehp.1003123
10.1002/glia.23908
10.1029/2019gh000222
10.1016/s0006-8993(01)01988-6
10.1016/j.neuro.2009.08.001
10.1016/j.it.2020.07.004
10.1016/s0169-328x(02)00642-3
10.1016/j.microc.2009.03.008
10.1111/j.1471-4159.2008.05683.x
10.1016/s0006-8993(01)02628-2
10.1016/j.chemosphere.2008.09.019
10.1002/jnr.20375
10.1016/j.etap.2004.07.008
10.1016/S0161-813X(01)00076-6
10.1002/jnr.23290
10.1016/j.envint.2018.12.016
10.1016/j.molbrainres.2004.05.022
10.1007/s00204-017-2042-6
10.1016/j.neuro.2004.03.001
10.1093/toxsci/kfn201
10.1016/j.ecoenv.2020.110799
10.1016/j.envint.2020.106223
10.1016/j.bbrc.2007.09.017
10.1097/WNR.0b013e32835fc827
10.1016/j.expneurol.2018.07.009
10.1006/taap.1998.8383
10.1016/j.mrgentox.2004.06.009
10.1093/toxsci/kfi227
10.1155/2018/6501031
10.1016/j.neuro.2020.04.004
10.1016/j.envres.2008.06.006
10.1006/taap.1994.1244
10.1016/j.neuro.2006.01.010
10.1016/j.tiv.2016.10.001
10.1038/srep04329
10.1016/j.scitotenv.2007.11.025
10.1089/neu.2010.1351
10.1016/0006-8993(93)90680-l
10.1016/0006-8993(90)91546-s
10.1016/j.cmet.2011.08.016
10.1016/j.neubiorev.2020.07.039
10.1002/(SICI)1097-4547(19980801)53:3<361::AID-JNR10>3.0.CO;2-8
10.1080/15287394.2012.697840
10.1371/journal.pone.0162822
10.1152/physrev.00042.2016
10.1016/j.molbrainres.2005.02.006
10.1523/jneurosci.3547-03.2004
10.1016/s0891-5849(01)00526-3
10.3390/nu11112585
10.3390/ijms17071121
10.3390/ijerph14010074
10.3390/antiox6030062
10.3390/ijms20020309
10.1042/BSR20180157
10.3390/cells8020184
10.1155/2010/656481
10.3389/conf.fphar.2010.02.00011
10.3390/antiox6030065
10.1093/function/zqaa016
10.3390/ijms20030571
10.3390/ijms20102435
10.3389/fnmol.2017.00088
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ISSN 0893-7648
1559-1182
IngestDate Tue Aug 05 11:17:19 EDT 2025
Fri Jul 25 19:01:14 EDT 2025
Mon Jul 21 05:24:59 EDT 2025
Tue Jul 01 01:04:51 EDT 2025
Thu Apr 24 23:05:30 EDT 2025
Fri Feb 21 02:48:25 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 9
Keywords Human
Brain
Pollutant
Astroglia
Metal
Glia
Mercury
Language English
License 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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References Toimela, Tahti (CR56) 1995; 9
Sandstrom, Eggermann, Charvet, Roux, Toni, Greggio, Broyer, Monnet-Tschudi, Stoppini (CR57) 2017; 38
Anderson, Burda, Ren, Ao, O’Shea, Kawaguchi, Coppola, Khakh, Deming, Sofroniew (CR95) 2016; 532
Kraft, Hu, Yoon, Yan, Xiao, Wang, Gil, Brown, Wilhelmsson, Restivo, Cirrito, Holtzman, Kim, Pekny, Lee (CR90) 2013; 27
Farina, Aschner, Rocha (CR14) 2011; 256
Shanker, Syversen, Aschner (CR44) 2003; 95
Jimenez-Blasco, Santofimia-Castano, Gonzalez, Almeida, Bolanos (CR113) 2015; 22
CR35
De Simone, Caloni, Gribaldo, Coccini (CR99) 2017; 36
Shanker, Aschner (CR118) 2001; 66
Karagas, Choi, Oken, Horvat, Schoeny, Kamai, Cowell, Grandjean, Korrick (CR27) 2012; 120
Chang, Pai, Chen, Guo, Su, Lee (CR28) 2008; 108
Liu, Xu, Yang, Deng, Xu, Feng (CR112) 2016; 53
Tilg, Trehu, Atkins, Dinarello, Mier (CR103) 1994; 83
Shapiro, Chan (CR73) 2008; 74
Ishihara, Itoh, Oguro, Chiba, Ueno, Tsuji, Vogel, Yamazaki (CR60) 2019; 9
Tiffany-Castiglion, Qian (CR71) 2001; 22
Huttunen, Peltokangas, Gynther, Natunen, Hiltunen, Auriola, Ruponen, Vellonen, Huttunen (CR70) 2019; 9
Ke, Sidoryk-Wegrzynowicz, Pajarillo, Rizor, Soares, Lee, Aschner (CR41) 2019
CR48
Nesic, Sundberg, Herrera, Mokkapati, Lee, Narayana (CR138) 2010; 27
Toyama, Sumi, Shinkai, Yasutake, Taguchi, Tong, Yamamoto, Kumagai (CR108) 2007; 363
Shanker, Mutkus, Walker, Aschner (CR144) 2002; 106
Arrifano, Del Carmen Rodriguez Martin-Doimeadios, Jimenez-Moreno, Augusto-Oliveira, Rogerio Souza-Monteiro, Paraense, Rodrigues Machado, Farina, Macchi, do Nascimento, Crespo-Lopez (CR86) 2018; 68
Toyama, Shinkai, Yasutake, Uchida, Yamamoto, Kumagai (CR111) 2011; 119
Yin, Albrecht, Syversen, Jiang, Summar, Rocha, Farina, Aschner (CR96) 2009; 55
Aschner (CR32) 1996; 17
Marty, Atchison (CR18) 1998; 150
Yilmaz, Yilmaz, Tutkun, Uysal, Carman, Dilber, Ercan (CR85) 2014; 52
Stoiber, Bonacker, Bohm, Bolt, Thier, Degen, Unger (CR21) 2004; 563
Shaw, Mottet, Body, Luschei (CR55) 1975; 80
Sofroniew (CR45) 2020; 41
Aschner, Rising, Mullaney (CR76) 1996; 17
Aragao, Teixeira, Fagundes, Fernandes, Fernandes, da Silva, Amado, Sagica, Oliveira, Crespo-Lopez, Maia, Lima (CR74) 2018; 2018
Vendrell, Carrascal, Campos, Abián, Suñol (CR19) 2010; 242
Bylicky, Mueller, Day (CR88) 2018; 2018
Farina, Aschner (CR15) 2017; 18
CR54
Charleston, Bolender, Mottet, Body, Vahter, Burbacher (CR64) 1994; 129
CR53
CR52
CR51
CR50
CR131
Aschner, Eberle, Goderie, Kimelberg (CR67) 1990; 521
Aschner, Eberle, Miller, Kimelberg (CR69) 1990; 530
Kim, Takahashi, Lee, Hwang, Naganuma (CR104) 2012; 37
CR139
Santana, Bittencourt, Nascimento, Fernandes, Teixeira, Fernandes, Freitas Silva, Nogueira, Amado, Crespo-Lopez, Maia, Lima (CR63) 2019; 51
Shao, Zhang, Tang, Zhang, Zhou, Yin, Zhou, Huang, Liu, Wawrousek, Chen, Li, Xu, Zhou, Hu, Zhou (CR93) 2012; 494
Fonfría, Vilaró, Babot, Rodríguez-Farré, Suñol (CR24) 2005; 79
Nakagawa, Izumi, Takada-Takatori, Akaike, Kume (CR37) 2019; 519
Shao, Wang, Langlois, Mironov, Chan (CR78) 2019; 57
Kirkley, Popichak, Afzali, Legare, Tjalkens (CR36) 2017; 14
Dare, Li, Zhivotovsky, Yuan, Ceccatelli (CR128) 2001; 30
Katsouri, Birch, Renziehausen, Zach, Aman, Steeds, Bonsu, Palmer, Mirzaei, Ries, Sastre (CR89) 2020; 68
Roda, Coccini, Acerbi, Castoldi, Bernocchi, Manzo (CR58) 2008; 35
Nielsen, Nagelhus, Amiry-Moghaddam, Bourque, Agre, Ottersen (CR135) 1997; 17
Eskes, Honegger, Juillerat-Jeanneret, Monnet-Tschudi (CR39) 2002; 37
Heimfarth, Delgado, Mignori, Gelain, Moreira, Pessoa-Pureur (CR61) 2018; 92
Zhang, Xu, Liu, Erokwu, Zhao, Flask, Ramos-Estebanez, Farr, LaManna, Boron, Yu (CR133) 2019; 14
Shanker, Aschner (CR43) 2003; 110
CR147
CR145
Crespo-Lopez, Costa-Malaquias, Oliveira, Miranda, Arrifano, Souza-Monteiro, Sagica, Fontes-Junior, Maia, Macchi, do Nascimento JL (CR10) 2016; 11
Crespo-Lopez, Macedo, Arrifano, Pinheiro Mda, do Nascimento JL, Herculano AM (CR11) 2011; 37
Nevado, Martin-Doimeadios, Moreno, do Nascimento, Herculano, Crespo-Lopez (CR72) 2009; 93
Caballero, Olguin, Campos, Farina, Ballester, Lopez-Espinosa, Llop, Rodríguez-Farré, Suñol (CR20) 2017; 59
Augusto-Oliveira, Arrifano, Takeda, Lopes-Araujo, Santos-Sacramento, Anthony, Verkhratsky, Crespo-Lopez (CR34) 2020; 118
Aschner, Yao, Allen, Tan (CR119) 2000; 37
Yee, Choi (CR125) 1996; 17
Malfa, Tomasello, Sinatra, Villaggio, Amenta, Avola, Renis (CR46) 2014; 92
Aschner, Kimelberg (CR87) 1991; 12
Fretham, Caito, Martinez-Finley, Aschner (CR13) 2012; 1
Lohren, Blagojevic, Fitkau, Ebert, Schildknecht, Leist, Schwerdtle (CR80) 2015; 32
Pierozan, Biasibetti, Schmitz, Avila, Fernandes, Pessoa-Pureur, Wyse (CR81) 2017; 54
Monnet-Tschudi, Zurich, Honegger (CR102) 1996; 741
Ni, Li, Rocha, Farina, Aschner (CR30) 2012; 75
Chakrabarti, Bai (CR142) 2000; 74
Moser (CR143) 1989; 8
Vicente, Boer, Leite, Silva, Tramontina, Porciuncula, Dalmaz, Goncalves (CR84) 2004; 25
Allen, Shanker, Aschner (CR116) 2001; 894
Fujimura, Usuki, Sawada, Takashima (CR59) 2009; 30
Dos Santos, Lopez-Granero, Farina, Rocha, Bowman, Aschner (CR146) 2018; 113
Godefroy, Gosselin, Yasutake, Fujimura, Combadiere, Maury-Brachet, Laclau, Rakwal, Melik-Parsadaniantz, Bourdineaud, Rostene (CR105) 2012; 125
Shanker, Aschner, Syversen, Aschner (CR124) 2004; 128
Belanger, Allaman, Magistretti (CR132) 2011; 14
Faulkner, Herrmann, Woo, Tansey, Doan, Sofroniew (CR94) 2004; 24
Kaur, Aschner, Syversen (CR127) 2006; 27
Hirooka, Yamamoto, Yasutake, Eto, Kaji (CR141) 2013; 38
Clarkson, Magos (CR5) 2006; 36
Nagelhus, Ottersen (CR136) 2013; 93
Dowell, Johnson (CR114) 2013; 8
el-Fawal, Gong, Little, Evans (CR82) 1996; 17
Farina, Cereser, Portela, Mendez, Porciuncula, Fornaguera, Goncalves, Wofchuk, Rocha, Souza (CR83) 2005; 19
Shanker, Syversen, Aschner, Aschner (CR107) 2005; 137
Allen, El-Oqayli, Aschner, Syversen, Sonnewald (CR130) 2001; 908
Shinozaki, Nomura, Iwatsuki, Moriyama, Gachet, Koizumi (CR98) 2014; 4
Basu, Horvat, Evers, Zastenskaya, Weihe, Tempowski (CR3) 2018; 126
Teixeira, de Oliveira, Leao, Fagundes, Fernandes, Fernandes, da Silva, Amado, Sagica, de Oliveira, Crespo-Lopez, Maia, Lima (CR75) 2018; 11
CR8
Farina, Rocha, Aschner (CR22) 2011; 89
Fonfría, Rodríguez-Farré, Suñol (CR23) 2001; 41
Mutkus, Aschner, Syversen, Aschner (CR120) 2005; 107
Bittencourt, Dionizio, Nascimento, Puty, Leao, Luz, Silva, Amado, Leite, Buzalaf, Crespo-Lopez, Maia, Lima (CR62) 2019; 11
Igarashi, Tsujita, Suzuki, Kwee, Nakada (CR134) 2013; 24
Yin, Jiang, Syversen, Rocha, Farina, Aschner (CR68) 2008; 107
Takemoto, Ishihara, Tsuji, Kawamoto, Yamazaki (CR110) 2016; 3
Fujiyama, Hirayama, Yasutake (CR106) 1994; 47
Shanker, Allen, Mutkus, Aschner (CR117) 2001; 914
Aschner, Du, Gannon, Kimelberg (CR115) 1993; 602
Reuben, Frischtak, Berky, Ortiz, Morales, Hsu-Kim, Pendergast, Pan (CR26) 2020; 4
Wang, Jiang, Yin, Aschner, Cai (CR109) 2009; 107
Ercal, Gurer-Orhan, Aykin-Burns (CR17) 2001; 1
CR16
Calabrese (CR31) 2008; 38
Ni, Li, Yin, Sidoryk-Wegrzynowicz, Jiang, Farina, Rocha, Syversen, Aschner (CR101) 2011; 59
Verkhratsky, Nedergaard (CR40) 2018; 98
Bertossi, Girolamo, Errede, Virgintino, Elia, Ambrosi, Roncali (CR123) 2004; 25
Morken, Sonnewald, Aschner, Syversen (CR77) 2005; 87
Sharma, Sanka, Kalina, Scheringer (CR4) 2019; 125
Debes, Weihe, Grandjean (CR29) 2016; 74
Santos-Sacramento, Arrifano, Lopes-Araujo, Augusto-Oliveira, Albuquerque-Santos, Takeda, Souza-Monteiro, Macchido Nascimento, Lima, Crespo-Lopez (CR1) 2021; 208
Freire, Lima, Nascimento, Gomes-Leal, Pereira (CR65) 2020; 201
CR91
Heithoff, George, Phares, Zuidhoek, Munoz-Ballester, Robel (CR148) 2021; 69
Ramon, Murcia, Ballester, Rebagliato, Lacasana, Vioque, Llop, Amurrio, Aguinagalde, Marco, Leon, Ibarluzea, Ribas-Fito (CR7) 2008; 392
Crespo-Lopez, Macedo, Pereira, Arrifano, Picanco-Diniz, do Nascimento JL, Herculano AM (CR12) 2009; 60
Crespo-Lopez, Lima de Sa, Herculano, Rodriguez Burbano, Martins do Nascimento (CR9) 2007; 33
Briz, Suñol (CR49) 2011; 758
Allen, Shanker, Tan, Aschner (CR122) 2002; 23
Takahashi, Fujimura, Koyama, Kanazawa, Usuki, Nishizawa, Shimohata (CR140) 2017; 12
Caito, Zeng, Aschner, Aschner (CR47) 2014; 9
Monnet-Tschudi (CR100) 1998; 53
Struzynska, Bubko, Walski, Rafalowska (CR42) 2001; 165
Yamamoto, Takeya, Ikeshima-Kataoka, Yasui, Kawasaki, Shiraishi, Majima, Shiraishi, Uezono, Sasaki, Eto (CR137) 2012; 37
Santos-Lima, Mourao, Carvalho, Souza-Marques, Vega, Goncalves, Argollo, Menezes-Filho, Abreu, Hacon (CR25) 2020; 79
Rothhammer, Mascanfroni, Bunse, Takenaka, Kenison, Mayo, Chao, Patel, Yan, Blain, Alvarez, Kébir, Anandasabapathy, Izquierdo, Jung, Obholzer, Pochet, Clish, Prinz, Prat, Antel, Quintana (CR92) 2016; 22
Sanfeliu, Sebastia, Ki (CR79) 2001; 22
Yin, Lee, Ni, Jiang, Milatovic, Rongzhu, Farina, Rocha, Aschner (CR126) 2011; 32
Jha, Morrison (CR129) 2018; 309
Takemoto, Ishihara, Ishida, Yamazaki (CR38) 2015; 40
Heimfarth, Delgado, Mingori, Moresco, Pureur, Gelain, Moreira (CR66) 2018; 284
Grandjean, Satoh, Murata, Eto (CR6) 2010; 118
Noguchi, Shinozaki, Fujishita, Shibata, Imura, Morizawa, Gachet, Koizumi (CR97) 2013; 8
Allen, Mutkus, Aschner (CR121) 2001; 902
Li, Xia, Zorec, Parpura, Verkhratsky (CR33) 2021; 1752
Crespo-Lopez, Augusto-Oliveira, Lopes-Araújo, Santos-Sacramento, Yuki Takeda, Macchi, do Nascimento JLM, Maia CSF, Lima RR, Arrifano GP (CR2) 2021; 146
M Aschner (2420_CR69) 1990; 530
G Shanker (2420_CR117) 2001; 914
I Vendrell (2420_CR19) 2010; 242
C Eskes (2420_CR39) 2002; 37
AA Dos Santos (2420_CR146) 2018; 113
Y Ishihara (2420_CR60) 2019; 9
G Shanker (2420_CR118) 2001; 66
TW Clarkson (2420_CR5) 2006; 36
HA el-Fawal (2420_CR82) 1996; 17
2420_CR8
MS Kim (2420_CR104) 2012; 37
C Sanfeliu (2420_CR79) 2001; 22
M Aschner (2420_CR76) 1996; 17
Z Yin (2420_CR96) 2009; 55
ME Crespo-Lopez (2420_CR10) 2016; 11
T Takemoto (2420_CR38) 2015; 40
W Aragao (2420_CR74) 2018; 2018
A Reuben (2420_CR26) 2020; 4
EJ Calabrese (2420_CR31) 2008; 38
V Briz (2420_CR49) 2011; 758
M Aschner (2420_CR32) 1996; 17
MAM Freire (2420_CR65) 2020; 201
M Farina (2420_CR14) 2011; 256
L Wang (2420_CR109) 2009; 107
R Ramon (2420_CR7) 2008; 392
Y Noguchi (2420_CR97) 2013; 8
JA Dowell (2420_CR114) 2013; 8
J Fujiyama (2420_CR106) 1994; 47
ME Crespo-Lopez (2420_CR11) 2011; 37
FB Teixeira (2420_CR75) 2018; 11
F Monnet-Tschudi (2420_CR102) 1996; 741
M Aschner (2420_CR115) 1993; 602
G Shanker (2420_CR124) 2004; 128
L Heimfarth (2420_CR61) 2018; 92
D Jimenez-Blasco (2420_CR113) 2015; 22
S Yee (2420_CR125) 1996; 17
M Farina (2420_CR15) 2017; 18
JW Allen (2420_CR121) 2001; 902
E Tiffany-Castiglion (2420_CR71) 2001; 22
TS Morken (2420_CR77) 2005; 87
2420_CR48
F Debes (2420_CR29) 2016; 74
T Toyama (2420_CR108) 2007; 363
G Shanker (2420_CR144) 2002; 106
H Igarashi (2420_CR134) 2013; 24
EA Nagelhus (2420_CR136) 2013; 93
FM Yilmaz (2420_CR85) 2014; 52
W Liu (2420_CR112) 2016; 53
P Grandjean (2420_CR6) 2010; 118
ME Crespo-Lopez (2420_CR9) 2007; 33
T Toyama (2420_CR111) 2011; 119
GA Malfa (2420_CR46) 2014; 92
BM Sharma (2420_CR4) 2019; 125
SK Chakrabarti (2420_CR142) 2000; 74
N Basu (2420_CR3) 2018; 126
MK Jha (2420_CR129) 2018; 309
CD Santos-Lima (2420_CR25) 2020; 79
A Verkhratsky (2420_CR40) 2018; 98
T Ke (2420_CR41) 2019
MR Karagas (2420_CR27) 2012; 120
E Roda (2420_CR58) 2008; 35
D Godefroy (2420_CR105) 2012; 125
E Vicente (2420_CR84) 2004; 25
JW Chang (2420_CR28) 2008; 108
N Ercal (2420_CR17) 2001; 1
2420_CR54
2420_CR53
M Aschner (2420_CR67) 1990; 521
H Tilg (2420_CR103) 1994; 83
2420_CR50
2420_CR52
T Stoiber (2420_CR21) 2004; 563
2420_CR51
E Fonfría (2420_CR23) 2001; 41
M Ni (2420_CR30) 2012; 75
JJB Nevado (2420_CR72) 2009; 93
M Aschner (2420_CR119) 2000; 37
CM Shaw (2420_CR55) 1975; 80
AW Kraft (2420_CR90) 2013; 27
E Fonfría (2420_CR24) 2005; 79
J Sandstrom (2420_CR57) 2017; 38
MV Sofroniew (2420_CR45) 2020; 41
U De Simone (2420_CR99) 2017; 36
Z Yin (2420_CR126) 2011; 32
ME Crespo-Lopez (2420_CR2) 2021; 146
Z Yin (2420_CR68) 2008; 107
JR Faulkner (2420_CR94) 2004; 24
T Takahashi (2420_CR140) 2017; 12
LO Bittencourt (2420_CR62) 2019; 11
G Arrifano (2420_CR86) 2018; 68
L Katsouri (2420_CR89) 2020; 68
2420_CR35
P Pierozan (2420_CR81) 2017; 54
AM Shapiro (2420_CR73) 2008; 74
BP Heithoff (2420_CR148) 2021; 69
E Dare (2420_CR128) 2001; 30
H Lohren (2420_CR80) 2015; 32
JW Allen (2420_CR130) 2001; 908
T Hirooka (2420_CR141) 2013; 38
KS Kirkley (2420_CR36) 2017; 14
S Nielsen (2420_CR135) 1997; 17
JS Charleston (2420_CR64) 1994; 129
J Huttunen (2420_CR70) 2019; 9
M Belanger (2420_CR132) 2011; 14
O Nesic (2420_CR138) 2010; 27
V Rothhammer (2420_CR92) 2016; 22
L Santos-Sacramento (2420_CR1) 2021; 208
JW Allen (2420_CR116) 2001; 894
Y Zhang (2420_CR133) 2019; 14
G Shanker (2420_CR44) 2003; 95
L Struzynska (2420_CR42) 2001; 165
VC Moser (2420_CR143) 1989; 8
M Ni (2420_CR101) 2011; 59
TA Toimela (2420_CR56) 1995; 9
M Aschner (2420_CR87) 1991; 12
2420_CR131
ME Crespo-Lopez (2420_CR12) 2009; 60
M Yamamoto (2420_CR137) 2012; 37
F Monnet-Tschudi (2420_CR100) 1998; 53
M Farina (2420_CR22) 2011; 89
2420_CR139
S Nakagawa (2420_CR37) 2019; 519
S Caito (2420_CR47) 2014; 9
L Santana (2420_CR63) 2019; 51
M Fujimura (2420_CR59) 2009; 30
P Kaur (2420_CR127) 2006; 27
2420_CR16
L Mutkus (2420_CR120) 2005; 107
W Shao (2420_CR93) 2012; 494
G Shanker (2420_CR107) 2005; 137
MA Anderson (2420_CR95) 2016; 532
T Takemoto (2420_CR110) 2016; 3
JW Allen (2420_CR122) 2002; 23
G Shanker (2420_CR43) 2003; 110
B Caballero (2420_CR20) 2017; 59
B Li (2420_CR33) 2021; 1752
2420_CR147
2420_CR91
2420_CR145
L Heimfarth (2420_CR66) 2018; 284
Y Shinozaki (2420_CR98) 2014; 4
M Farina (2420_CR83) 2005; 19
MS Marty (2420_CR18) 1998; 150
Y Shao (2420_CR78) 2019; 57
SJ Fretham (2420_CR13) 2012; 1
M Bertossi (2420_CR123) 2004; 25
MA Bylicky (2420_CR88) 2018; 2018
M Augusto-Oliveira (2420_CR34) 2020; 118
References_xml – volume: 9
  start-page: e98161
  issue: 5
  year: 2014
  ident: CR47
  article-title: Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0098161
– volume: 80
  start-page: 451
  issue: 3
  year: 1975
  end-page: 470
  ident: CR55
  article-title: Variability of neuropathologic lesions in experimental methylmercurial encephalopathy in primates
  publication-title: Am J Pathol
– volume: 1752
  start-page: 147234
  year: 2021
  ident: CR33
  article-title: Astrocytes in heavy metal neurotoxicity and neurodegeneration
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2020.147234
– volume: 22
  start-page: 317
  issue: 3
  year: 2001
  end-page: 327
  ident: CR79
  article-title: Methylmercury neurotoxicity in cultures of human neurons, astrocytes, neuroblastoma cells
  publication-title: Neurotoxicology
  doi: 10.1016/s0161-813x(01)00015-8
– volume: 14
  start-page: e0218415
  issue: 6
  year: 2019
  ident: CR133
  article-title: Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0218415
– volume: 60
  start-page: 212
  issue: 4
  year: 2009
  end-page: 220
  ident: CR12
  article-title: Mercury and human genotoxicity: critical considerations and possible molecular mechanisms
  publication-title: Pharmacol Res
  doi: 10.1016/j.phrs.2009.02.011
– volume: 113
  start-page: 328
  year: 2018
  end-page: 336
  ident: CR146
  article-title: Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells
  publication-title: Food Chem
  doi: 10.1016/j.fct.2018.01.057
– year: 2019
  ident: CR41
  article-title: Role of astrocytes in manganese neurotoxicity revisited
  publication-title: Neurochem Res
  doi: 10.1007/s11064-019-02881-7
– ident: CR16
– ident: CR51
– volume: 107
  start-page: 231
  issue: 3
  year: 2005
  end-page: 245
  ident: CR120
  article-title: Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells
  publication-title: Biol Trace Elem Res
  doi: 10.1385/BTER:107:3:231
– volume: 32
  start-page: 200
  year: 2015
  end-page: 208
  ident: CR80
  article-title: Toxicity of organic and inorganic mercury species in differentiated human neurons and human astrocytes
  publication-title: J Trace Elem Med Biol
  doi: 10.1016/j.jtemb.2015.06.008
– volume: 11
  start-page: 390
  issue: 2
  year: 2019
  end-page: 403
  ident: CR62
  article-title: Proteomic approach underlying the hippocampal neurodegeneration caused by low doses of methylmercury after long-term exposure in adult rats
  publication-title: Metallomics
  doi: 10.1039/c8mt00297e
– volume: 3
  start-page: 63
  issue: 2
  year: 2016
  end-page: 65
  ident: CR110
  article-title: Transcription factor activation in rat primary astrocytes exposed to methylmercury
  publication-title: Fundam Toxicol Sci
  doi: 10.2131/fts.3.63
– ident: CR54
– volume: 37
  start-page: 43
  issue: 1
  year: 2002
  end-page: 52
  ident: CR39
  article-title: Microglial reaction induced by noncytotoxic methylmercury treatment leads to neuroprotection via interactions with astrocytes and IL-6 release
  publication-title: Glia
  doi: 10.1002/glia.10019
– volume: 37
  start-page: 1275
  issue: 6
  year: 2012
  end-page: 1278
  ident: CR104
  article-title: Methylmercury induces CCL2 expression through activation of NF-kappaB in human 1321N1 astrocytes
  publication-title: J Toxicol Sci
  doi: 10.2131/jts.37.1275
– volume: 17
  start-page: 17
  issue: 1
  year: 1996
  end-page: 26
  ident: CR125
  article-title: Oxidative stress in neurotoxic effects of methylmercury poisoning
  publication-title: Neurotoxicology
– ident: CR8
– volume: 25
  start-page: 849
  issue: 5
  year: 2004
  end-page: 857
  ident: CR123
  article-title: Effects of methylmercury on the microvasculature of the developing brain
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2004.01.005
– volume: 17
  start-page: 171
  issue: 1
  year: 1997
  end-page: 180
  ident: CR135
  article-title: Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.17-01-00171.1997
– volume: 242
  start-page: 109
  issue: 1
  year: 2010
  end-page: 118
  ident: CR19
  article-title: Methylmercury disrupts the balance between phosphorylated and non-phosphorylated cofilin in primary cultures of mice cerebellar granule cells a proteomic study
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2009.09.022
– volume: 89
  start-page: 555
  issue: 15–16
  year: 2011
  end-page: 563
  ident: CR22
  article-title: Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies
  publication-title: Life Sci
  doi: 10.1016/j.lfs.2011.05.019
– volume: 37
  start-page: 199
  issue: 2–3
  year: 2000
  end-page: 206
  ident: CR119
  article-title: Methylmercury alters glutamate transport in astrocytes
  publication-title: Neurochem Int
  doi: 10.1016/s0197-0186(00)00023-1
– volume: 125
  start-page: 209
  issue: 1
  year: 2012
  end-page: 218
  ident: CR105
  article-title: The chemokine CCL2 protects against methylmercury neurotoxicity
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfr252
– volume: 83
  start-page: 113
  issue: 1
  year: 1994
  end-page: 118
  ident: CR103
  article-title: Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55
  publication-title: Blood
  doi: 10.1182/blood.V83.1.113.113
– volume: 40
  start-page: 199
  issue: 1
  year: 2015
  end-page: 205
  ident: CR38
  article-title: Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released from astrocytes in response to methylmercury
  publication-title: Environ Toxicol Pharmacol
  doi: 10.1016/j.etap.2015.06.010
– volume: 902
  start-page: 92
  issue: 1
  year: 2001
  end-page: 100
  ident: CR121
  article-title: Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)02375-7
– volume: 8
  start-page: e57898
  issue: 2
  year: 2013
  ident: CR97
  article-title: Astrocytes protect neurons against methylmercury via ATP/P2Y(1) receptor-mediated pathways in astrocytes
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0057898
– volume: 106
  start-page: 1
  issue: 1–2
  year: 2002
  end-page: 11
  ident: CR144
  article-title: Methylmercury enhances arachidonic acid release and cytosolic phospholipase A2 expression in primary cultures of neonatal astrocytes
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/S0169-328X(02)00403-5
– volume: 38
  start-page: 463
  issue: 5
  year: 2008
  end-page: 471
  ident: CR31
  article-title: Astrocytes: adaptive responses to low doses of neurotoxins
  publication-title: Crit Rev Toxicol
  doi: 10.1080/10408440802004023
– volume: 519
  start-page: 777
  issue: 4
  year: 2019
  end-page: 782
  ident: CR37
  article-title: Increased CCL6 expression in astrocytes and neuronal protection from neuron-astrocyte interactions
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2019.09.030
– volume: 41
  start-page: 819
  issue: 7
  year: 2001
  end-page: 833
  ident: CR23
  article-title: Mercury interaction with the GABA(A) receptor modulates the benzodiazepine binding site in primary cultures of mouse cerebellar granule cells
  publication-title: Neuropharmacology
  doi: 10.1016/s0028-3908(01)00130-7
– volume: 52
  start-page: 32
  issue: 1
  year: 2014
  end-page: 38
  ident: CR85
  article-title: Serum biochemical markers of central nerve system damage in children with acute elemental mercury intoxication
  publication-title: Clin Toxicol (Phila)
  doi: 10.3109/15563650.2013.860986
– ident: CR147
– volume: 59
  start-page: 197
  year: 2017
  end-page: 209
  ident: CR20
  article-title: Methylmercury-induced developmental toxicity is associated with oxidative stress and cofilin phosphorylation Cellular and human studies
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2016.05.018
– volume: 18
  start-page: 267
  year: 2017
  end-page: 286
  ident: CR15
  article-title: Methylmercury-induced neurotoxicity: focus on pro-oxidative events and related consequences
  publication-title: Adv Neurobiol
  doi: 10.1007/978-3-319-60189-2_13
– volume: 17
  start-page: 663
  issue: 3–4
  year: 1996
  end-page: 669
  ident: CR32
  article-title: Astrocytes as modulators of mercury-induced neurotoxicity
  publication-title: Neurotoxicology
– volume: 57
  start-page: 96
  year: 2019
  end-page: 104
  ident: CR78
  article-title: Proteome changes in methylmercury-exposed mouse primary cerebellar granule neurons and astrocytes
  publication-title: Toxicol In Vitro
  doi: 10.1016/j.tiv.2019.02.013
– volume: 66
  start-page: 998
  issue: 5
  year: 2001
  end-page: 1002
  ident: CR118
  article-title: Identification and characterization of uptake systems for cystine and cysteine in cultured astrocytes and neurons: evidence for methylmercury-targeted disruption of astrocyte transport
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.10066
– ident: CR91
– volume: 758
  start-page: 253
  year: 2011
  end-page: 265
  ident: CR49
  article-title: Homeostatic regulation of glutamate neurotransmission in primary neuronal cultures
  publication-title: Methods Mol Biol
  doi: 10.1007/978-1-61779-170-3_17
– volume: 1
  start-page: 32
  issue: 1
  year: 2012
  end-page: 38
  ident: CR13
  article-title: Mechanisms and modifiers of methylmercury-induced neurotoxicity
  publication-title: Toxicology research
  doi: 10.1039/C2TX20010D
– volume: 165
  start-page: 121
  issue: 2–3
  year: 2001
  end-page: 131
  ident: CR42
  article-title: Astroglial reaction during the early phase of acute lead toxicity in the adult rat brain
  publication-title: Toxicology
  doi: 10.1016/s0300-483x(01)00415-2
– volume: 32
  start-page: 291
  issue: 3
  year: 2011
  end-page: 299
  ident: CR126
  article-title: Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2011.01.004
– volume: 95
  start-page: 1
  issue: 1
  year: 2003
  end-page: 10
  ident: CR44
  article-title: Astrocyte-mediated methylmercury neurotoxicity
  publication-title: Biol Trace Elem Res
  doi: 10.1385/BTER:95:1:1
– volume: 53
  start-page: 2995
  issue: 5
  year: 2016
  end-page: 3009
  ident: CR112
  article-title: Tea polyphenols protect against methylmercury-induced cell injury in rat primary cultured astrocytes, involvement of oxidative stress and glutamate uptake/metabolism disorders
  publication-title: Mol Neurobiol
  doi: 10.1007/s12035-015-9161-y
– volume: 22
  start-page: 586
  issue: 6
  year: 2016
  end-page: 597
  ident: CR92
  article-title: Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
  publication-title: Nat Med
  doi: 10.1038/nm.4106
– volume: 17
  start-page: 107
  issue: 1
  year: 1996
  end-page: 116
  ident: CR76
  article-title: Differential sensitivity of neonatal rat astrocyte cultures to mercuric chloride (MC) and methylmercury (MeHg): studies on K+ and amino acid transport and metallothionein (MT) induction
  publication-title: Neurotoxicology
– volume: 68
  start-page: 1017
  issue: 5
  year: 2020
  end-page: 1030
  ident: CR89
  article-title: Ablation of reactive astrocytes exacerbates disease pathology in a model of Alzheimer's disease
  publication-title: Glia
  doi: 10.1002/glia.23759
– volume: 68
  start-page: 151
  year: 2018
  end-page: 158
  ident: CR86
  article-title: Assessing mercury intoxication in isolated/remote populations: increased S100B mRNA in blood in exposed riverine inhabitants of the Amazon
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2018.07.018
– volume: 284
  start-page: 161
  year: 2018
  end-page: 169
  ident: CR66
  article-title: Delayed neurochemical effects of prenatal exposure to MeHg in the cerebellum of developing rats
  publication-title: Toxicol Lett
  doi: 10.1016/j.toxlet.2017.12.006
– volume: 33
  start-page: 141
  issue: 2
  year: 2007
  end-page: 146
  ident: CR9
  article-title: Methylmercury genotoxicity: a novel effect in human cell lines of the central nervous system
  publication-title: Environ Int
  doi: 10.1016/j.envint.2006.08.005
– volume: 126
  start-page: 106001
  issue: 10
  year: 2018
  ident: CR3
  article-title: A state-of-the-science review of mercury biomarkers in human populations worldwide between 2000 and 2018
  publication-title: Environ Health Perspect
  doi: 10.1289/EHP3904
– volume: 37
  start-page: 749
  issue: 4
  year: 2012
  end-page: 763
  ident: CR137
  article-title: Increased expression of aquaporin-4 with methylmercury exposure in the brain of the common marmoset
  publication-title: J Toxicol Sci
  doi: 10.2131/jts.37.749
– volume: 530
  start-page: 245
  issue: 2
  year: 1990
  end-page: 250
  ident: CR69
  article-title: Interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling
  publication-title: Brain Res
  doi: 10.1016/0006-8993(90)91290-w
– volume: 22
  start-page: 577
  issue: 5
  year: 2001
  end-page: 592
  ident: CR71
  article-title: Astroglia as metal depots: molecular mechanisms for metal accumulation, storage and release
  publication-title: Neurotoxicology
  doi: 10.1016/s0161-813x(01)00050-x
– volume: 11
  start-page: 125
  year: 2018
  ident: CR75
  article-title: Exposure to inorganic mercury causes oxidative stress, cell death, and functional deficits in the motor cortex
  publication-title: Front Mol Neurosci
  doi: 10.3389/fnmol.2018.00125
– volume: 14
  start-page: 99
  issue: 1
  year: 2017
  ident: CR36
  article-title: Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity
  publication-title: J Neuroinflammation
  doi: 10.1186/s12974-017-0871-0
– volume: 36
  start-page: 463
  issue: 6
  year: 2017
  end-page: 477
  ident: CR99
  article-title: Human co-culture model of neurons and astrocytes to test acute cytotoxicity of neurotoxic compounds
  publication-title: Int J Toxicol
  doi: 10.1177/1091581817739428
– ident: CR52
– volume: 9
  start-page: 12860
  issue: 1
  year: 2019
  ident: CR70
  article-title: l-Type amino acid transporter 1 (LAT1/Lat1)-utilizing prodrugs can improve the delivery of drugs into neurons, astrocytes and microglia
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-49009-z
– ident: CR139
– volume: 27
  start-page: 187
  issue: 1
  year: 2013
  end-page: 198
  ident: CR90
  article-title: Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice
  publication-title: FASEB J
  doi: 10.1096/fj.12-208660
– volume: 47
  start-page: 1525
  issue: 9
  year: 1994
  end-page: 1530
  ident: CR106
  article-title: Mechanism of methylmercury efflux from cultured astrocytes
  publication-title: Biochem Pharmacol
  doi: 10.1016/0006-2952(94)90527-4
– volume: 38
  start-page: 837
  issue: 6
  year: 2013
  end-page: 845
  ident: CR141
  article-title: Expression of VEGF-related proteins in cultured human brain microvascular endothelial cells and pericytes after exposure to methylmercury
  publication-title: J Toxicol Sci
  doi: 10.2131/jts.38.837
– volume: 54
  start-page: 5752
  issue: 8
  year: 2017
  end-page: 5767
  ident: CR81
  article-title: Neurotoxicity of methylmercury in isolated astrocytes and neurons: the cytoskeleton as a main target
  publication-title: Mol Neurobiol
  doi: 10.1007/s12035-016-0101-2
– volume: 9
  start-page: 317
  issue: 3
  year: 1995
  end-page: 325
  ident: CR56
  article-title: Effects of mercury, methylmercury and aluminium on glial fibrillary acidic protein expression in rat cerebellar astrocyte cultures
  publication-title: Toxicology in vitro : an international journal published in association with BIBRA
  doi: 10.1016/0887-2333(95)00002-p
– volume: 914
  start-page: 159
  issue: 1–2
  year: 2001
  end-page: 165
  ident: CR117
  article-title: Methylmercury inhibits cysteine uptake in cultured primary astrocytes, but not in neurons
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)02791-3
– volume: 118
  start-page: 1137
  issue: 8
  year: 2010
  end-page: 1145
  ident: CR6
  article-title: Adverse effects of methylmercury: environmental health research implications
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.0901757
– volume: 36
  start-page: 609
  issue: 8
  year: 2006
  end-page: 662
  ident: CR5
  article-title: The toxicology of mercury and its chemical compounds
  publication-title: Crit Rev Toxicol
  doi: 10.1080/10408440600845619
– volume: 494
  start-page: 90
  issue: 7435
  year: 2012
  end-page: 94
  ident: CR93
  article-title: Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin
  publication-title: Nature
  doi: 10.1038/nature11748
– ident: CR145
– volume: 55
  start-page: 136
  issue: 1–3
  year: 2009
  end-page: 142
  ident: CR96
  article-title: Comparison of alterations in amino acids content in cultured astrocytes or neurons exposed to methylmercury separately or in co-culture
  publication-title: Neurochem Int
  doi: 10.1016/j.neuint.2009.01.015
– volume: 37
  start-page: 136
  issue: 1
  year: 2011
  end-page: 141
  ident: CR11
  article-title: Genotoxicity of mercury: contributing for the analysis of Amazonian populations
  publication-title: Environ Int
  doi: 10.1016/j.envint.2010.08.009
– volume: 532
  start-page: 195
  issue: 7598
  year: 2016
  end-page: 200
  ident: CR95
  article-title: Astrocyte scar formation aids central nervous system axon regeneration
  publication-title: Nature
  doi: 10.1038/nature17623
– volume: 22
  start-page: 1877
  issue: 11
  year: 2015
  end-page: 1889
  ident: CR113
  article-title: Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway
  publication-title: Cell Death Differ
  doi: 10.1038/cdd.2015.49
– volume: 51
  start-page: 19
  year: 2019
  end-page: 27
  ident: CR63
  article-title: Low doses of methylmercury exposure during adulthood in rats display oxidative stress, neurodegeneration in the motor cortex and lead to impairment of motor skills
  publication-title: J Trace Elem Med Biol
  doi: 10.1016/j.jtemb.2018.09.004
– volume: 256
  start-page: 405
  issue: 3
  year: 2011
  end-page: 417
  ident: CR14
  article-title: Oxidative stress in MeHg-induced neurotoxicity
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2011.05.001
– volume: 1
  start-page: 529
  issue: 6
  year: 2001
  end-page: 539
  ident: CR17
  article-title: Toxic metals and oxidative stress part I: mechanisms involved in metal-induced oxidative damage
  publication-title: Curr Top Med Chem
  doi: 10.2174/1568026013394831
– volume: 741
  start-page: 52
  issue: 1–2
  year: 1996
  end-page: 59
  ident: CR102
  article-title: Comparison of the developmental effects of two mercury compounds on glial cells and neurons in aggregate cultures of rat telencephalon
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(96)00895-5
– volume: 74
  start-page: 196
  issue: 4–5
  year: 2000
  end-page: 202
  ident: CR142
  article-title: Effects of protein-deficient nutrition during rat pregnancy and development on developmental hindlimb crossing due to methylmercury intoxication
  publication-title: Arch Toxicol
  doi: 10.1007/s002040000112
– ident: CR131
– volume: 12
  start-page: e0170623
  issue: 1
  year: 2017
  ident: CR140
  article-title: Methylmercury causes blood-brain barrier damage in rats via upregulation of vascular endothelial growth factor expression
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0170623
– volume: 17
  start-page: 531
  issue: 2
  year: 1996
  end-page: 539
  ident: CR82
  article-title: Exposure to methylmercury results in serum autoantibodies to neurotypic and gliotypic proteins
  publication-title: Neurotoxicology
– volume: 35
  start-page: 285
  issue: 3
  year: 2008
  end-page: 294
  ident: CR58
  article-title: Cerebellum cholinergic muscarinic receptor (subtype-2 and -3) and cytoarchitecture after developmental exposure to methylmercury: an immunohistochemical study in rat
  publication-title: J Chem Neuroanat
  doi: 10.1016/j.jchemneu.2008.01.003
– volume: 208
  start-page: 111686
  year: 2021
  ident: CR1
  article-title: Human neurotoxicity of mercury in the Amazon: a scoping review with insights and critical considerations
  publication-title: Ecotoxicol Environ Saf
  doi: 10.1016/j.ecoenv.2020.111686
– volume: 9
  start-page: 13899
  issue: 1
  year: 2019
  ident: CR60
  article-title: Neuroprotective activation of astrocytes by methylmercury exposure in the inferior colliculus
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-50377-9
– ident: CR35
– volume: 74
  start-page: 358
  year: 2016
  end-page: 369
  ident: CR29
  article-title: Cognitive deficits at age 22 years associated with prenatal exposure to methylmercury
  publication-title: Cortex
  doi: 10.1016/j.cortex.2015.05.017
– volume: 8
  start-page: e70163
  issue: 7
  year: 2013
  ident: CR114
  article-title: Mechanisms of Nrf2 protection in astrocytes as identified by quantitative proteomics and siRNA screening
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0070163
– volume: 120
  start-page: 799
  issue: 6
  year: 2012
  end-page: 806
  ident: CR27
  article-title: Evidence on the human health effects of low-level methylmercury exposure
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1104494
– volume: 8
  start-page: 85
  issue: 1
  year: 1989
  end-page: 93
  ident: CR143
  article-title: Screening approaches to neurotoxicity: a functional observational battery
  publication-title: J Am Coll Toxicol
  doi: 10.3109/10915818909009095
– volume: 93
  start-page: 1543
  issue: 4
  year: 2013
  end-page: 1562
  ident: CR136
  article-title: Physiological roles of aquaporin-4 in brain
  publication-title: Physiol Rev
  doi: 10.1152/physrev.00011.2013
– volume: 2018
  start-page: 7878050
  year: 2018
  ident: CR74
  article-title: Hippocampal dysfunction provoked by mercury chloride exposure: evaluation of cognitive impairment, oxidative stress, tissue injury and nature of cell death
  publication-title: Oxid Med Cell Longev
  doi: 10.1155/2018/7878050
– volume: 59
  start-page: 810
  issue: 5
  year: 2011
  end-page: 820
  ident: CR101
  article-title: Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity
  publication-title: Glia
  doi: 10.1002/glia.21153
– volume: 119
  start-page: 1117
  issue: 8
  year: 2011
  end-page: 1122
  ident: CR111
  article-title: Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1003123
– volume: 69
  start-page: 436
  issue: 2
  year: 2021
  end-page: 472
  ident: CR148
  article-title: Astrocytes are necessary for blood-brain barrier maintenance in the adult mouse brain
  publication-title: Glia
  doi: 10.1002/glia.23908
– volume: 4
  start-page: e2019GH000222
  issue: 5
  year: 2020
  ident: CR26
  article-title: Elevated hair mercury levels are associated with neurodevelopmental deficits in children living near artisanal and small-scale gold mining in Peru
  publication-title: GeoHealth
  doi: 10.1029/2019gh000222
– volume: 894
  start-page: 131
  issue: 1
  year: 2001
  end-page: 140
  ident: CR116
  article-title: Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)01988-6
– volume: 30
  start-page: 1000
  issue: 6
  year: 2009
  end-page: 1007
  ident: CR59
  article-title: Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2009.08.001
– volume: 41
  start-page: 758
  issue: 9
  year: 2020
  end-page: 770
  ident: CR45
  article-title: Astrocyte reactivity: subtypes, states, and functions in CNS innate immunity
  publication-title: Trends Immunol
  doi: 10.1016/j.it.2020.07.004
– volume: 110
  start-page: 85
  issue: 1
  year: 2003
  end-page: 91
  ident: CR43
  article-title: Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/s0169-328x(02)00642-3
– ident: CR50
– volume: 93
  start-page: 12
  issue: 1
  year: 2009
  end-page: 16
  ident: CR72
  article-title: Mercury speciation analysis on cell lines of the human central nervous system to explain genotoxic effects
  publication-title: Microchem J
  doi: 10.1016/j.microc.2009.03.008
– volume: 107
  start-page: 1083
  issue: 4
  year: 2008
  end-page: 1090
  ident: CR68
  article-title: The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2008.05683.x
– volume: 908
  start-page: 149
  issue: 2
  year: 2001
  end-page: 154
  ident: CR130
  article-title: Methylmercury has a selective effect on mitochondria in cultured astrocytes in the presence of [U-(13)C]glutamate
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)02628-2
– volume: 74
  start-page: 112
  issue: 1
  year: 2008
  end-page: 118
  ident: CR73
  article-title: Characterization of demethylation of methylmercury in cultured astrocytes
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2008.09.019
– volume: 79
  start-page: 545
  issue: 4
  year: 2005
  end-page: 553
  ident: CR24
  article-title: Mercury compounds disrupt neuronal glutamate transport in cultured mouse cerebellar granule cells
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.20375
– volume: 19
  start-page: 249
  issue: 2
  year: 2005
  end-page: 253
  ident: CR83
  article-title: Methylmercury increases S100B content in rat cerebrospinal fluid
  publication-title: Environ Toxicol Pharmacol
  doi: 10.1016/j.etap.2004.07.008
– volume: 23
  start-page: 755
  issue: 6
  year: 2002
  end-page: 759
  ident: CR122
  article-title: The consequences of methylmercury exposure on interactive functions between astrocytes and neurons
  publication-title: Neurotoxicology
  doi: 10.1016/S0161-813X(01)00076-6
– volume: 92
  start-page: 95
  issue: 1
  year: 2014
  end-page: 103
  ident: CR46
  article-title: "Reactive" response evaluation of primary human astrocytes after methylmercury exposure
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.23290
– volume: 12
  start-page: 505
  issue: 3
  year: 1991
  end-page: 517
  ident: CR87
  article-title: The use of astrocytes in culture as model systems for evaluating neurotoxic-induced-injury
  publication-title: Neurotoxicology
– volume: 125
  start-page: 300
  year: 2019
  end-page: 319
  ident: CR4
  article-title: An overview of worldwide and regional time trends in total mercury levels in human blood and breast milk from 1966 to 2015 and their associations with health effects
  publication-title: Environ Int
  doi: 10.1016/j.envint.2018.12.016
– volume: 128
  start-page: 48
  issue: 1
  year: 2004
  end-page: 57
  ident: CR124
  article-title: Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/j.molbrainres.2004.05.022
– volume: 92
  start-page: 513
  issue: 1
  year: 2018
  end-page: 527
  ident: CR61
  article-title: Developmental neurotoxicity of the hippocampus following in utero exposure to methylmercury: impairment in cell signaling
  publication-title: Arch Toxicol
  doi: 10.1007/s00204-017-2042-6
– volume: 25
  start-page: 771
  issue: 5
  year: 2004
  end-page: 777
  ident: CR84
  article-title: Cerebrospinal fluid S100B increases reversibly in neonates of methyl mercury-intoxicated pregnant rats
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2004.03.001
– volume: 107
  start-page: 135
  issue: 1
  year: 2009
  end-page: 143
  ident: CR109
  article-title: Methylmercury toxicity and Nrf2-dependent detoxification in astrocytes
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfn201
– volume: 201
  start-page: 110799
  year: 2020
  ident: CR65
  article-title: Effects of methylmercury on the pattern of NADPH diaphorase expression and astrocytic activation in the rat
  publication-title: Ecotoxicol Environ Saf
  doi: 10.1016/j.ecoenv.2020.110799
– ident: CR53
– volume: 146
  start-page: 106223
  year: 2021
  ident: CR2
  article-title: Mercury: what can we learn from the Amazon?
  publication-title: Environ Int
  doi: 10.1016/j.envint.2020.106223
– volume: 363
  start-page: 645
  issue: 3
  year: 2007
  end-page: 650
  ident: CR108
  article-title: Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2007.09.017
– volume: 24
  start-page: 324
  issue: 6
  year: 2013
  end-page: 328
  ident: CR134
  article-title: Inhibition of aquaporin-4 significantly increases regional cerebral blood flow
  publication-title: Neuroreport
  doi: 10.1097/WNR.0b013e32835fc827
– volume: 309
  start-page: 23
  year: 2018
  end-page: 31
  ident: CR129
  article-title: Glia-neuron energy metabolism in health and diseases: new insights into the role of nervous system metabolic transporters
  publication-title: Exp Neurol
  doi: 10.1016/j.expneurol.2018.07.009
– volume: 150
  start-page: 98
  issue: 1
  year: 1998
  end-page: 105
  ident: CR18
  article-title: Elevations of intracellular Ca2+ as a probable contributor to decreased viability in cerebellar granule cells following acute exposure to methylmercury
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1006/taap.1998.8383
– volume: 563
  start-page: 97
  issue: 2
  year: 2004
  end-page: 106
  ident: CR21
  article-title: Disturbed microtubule function and induction of micronuclei by chelate complexes of mercury(II)
  publication-title: Mutat Res
  doi: 10.1016/j.mrgentox.2004.06.009
– volume: 87
  start-page: 169
  issue: 1
  year: 2005
  end-page: 175
  ident: CR77
  article-title: Effects of methylmercury on primary brain cells in mono- and co-culture
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfi227
– volume: 2018
  start-page: 6501031
  year: 2018
  ident: CR88
  article-title: Mechanisms of endogenous neuroprotective effects of astrocytes in brain injury
  publication-title: Oxid Med Cell Longev
  doi: 10.1155/2018/6501031
– volume: 79
  start-page: 48
  year: 2020
  end-page: 57
  ident: CR25
  article-title: Neuropsychological effects of mercury exposure in children and adolescents of the Amazon Region, Brazil
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2020.04.004
– volume: 108
  start-page: 334
  issue: 3
  year: 2008
  end-page: 339
  ident: CR28
  article-title: Cognitive function and blood methylmercury in adults living near a deserted chloralkali factory
  publication-title: Environ Res
  doi: 10.1016/j.envres.2008.06.006
– volume: 129
  start-page: 196
  issue: 2
  year: 1994
  end-page: 206
  ident: CR64
  article-title: Increases in the number of reactive glia in the visual cortex of Macaca fascicularis following subclinical long-term methyl mercury exposure
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1006/taap.1994.1244
– volume: 27
  start-page: 492
  issue: 4
  year: 2006
  end-page: 500
  ident: CR127
  article-title: Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2006.01.010
– volume: 38
  start-page: 124
  year: 2017
  end-page: 135
  ident: CR57
  article-title: Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing
  publication-title: Toxicol In Vitro
  doi: 10.1016/j.tiv.2016.10.001
– volume: 4
  start-page: 4329
  year: 2014
  ident: CR98
  article-title: Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission
  publication-title: Sci Rep
  doi: 10.1038/srep04329
– volume: 392
  start-page: 69
  issue: 1
  year: 2008
  end-page: 78
  ident: CR7
  article-title: Prenatal exposure to mercury in a prospective mother-infant cohort study in a Mediterranean area, Valencia, Spain
  publication-title: Sci Total Environ
  doi: 10.1016/j.scitotenv.2007.11.025
– ident: CR48
– volume: 27
  start-page: 1793
  issue: 10
  year: 2010
  end-page: 1803
  ident: CR138
  article-title: Vascular endothelial growth factor and spinal cord injury pain
  publication-title: J Neurotrauma
  doi: 10.1089/neu.2010.1351
– volume: 602
  start-page: 181
  issue: 2
  year: 1993
  end-page: 186
  ident: CR115
  article-title: Methylmercury-induced alterations in excitatory amino acid transport in rat primary astrocyte cultures
  publication-title: Brain Res
  doi: 10.1016/0006-8993(93)90680-l
– volume: 521
  start-page: 221
  issue: 1–2
  year: 1990
  end-page: 228
  ident: CR67
  article-title: Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system
  publication-title: Brain Res
  doi: 10.1016/0006-8993(90)91546-s
– volume: 14
  start-page: 724
  issue: 6
  year: 2011
  end-page: 738
  ident: CR132
  article-title: Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation
  publication-title: Cell Metab
  doi: 10.1016/j.cmet.2011.08.016
– volume: 118
  start-page: 331
  year: 2020
  end-page: 357
  ident: CR34
  article-title: Astroglia-specific contributions to the regulation of synapses, cognition and behaviour
  publication-title: Neurosci Biobehav Rev
  doi: 10.1016/j.neubiorev.2020.07.039
– volume: 53
  start-page: 361
  issue: 3
  year: 1998
  end-page: 367
  ident: CR100
  article-title: Induction of apoptosis by mercury compounds depends on maturation and is not associated with microglial activation
  publication-title: J Neurosci Res
  doi: 10.1002/(SICI)1097-4547(19980801)53:3<361::AID-JNR10>3.0.CO;2-8
– volume: 75
  start-page: 1091
  issue: 16–17
  year: 2012
  end-page: 1101
  ident: CR30
  article-title: Glia and methylmercury neurotoxicity
  publication-title: J Toxicol Environ Health A
  doi: 10.1080/15287394.2012.697840
– volume: 11
  start-page: e0162822
  issue: 9
  year: 2016
  ident: CR10
  article-title: Is low non-lethal concentration of methylmercury really safe? A report on genotoxicity with delayed cell proliferation
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0162822
– volume: 98
  start-page: 239
  issue: 1
  year: 2018
  end-page: 389
  ident: CR40
  article-title: Physiology of astroglia
  publication-title: Physiol Rev
  doi: 10.1152/physrev.00042.2016
– volume: 137
  start-page: 11
  issue: 1–2
  year: 2005
  end-page: 22
  ident: CR107
  article-title: Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/j.molbrainres.2005.02.006
– volume: 24
  start-page: 2143
  issue: 9
  year: 2004
  end-page: 2155
  ident: CR94
  article-title: Reactive astrocytes protect tissue and preserve function after spinal cord injury
  publication-title: J Neurosci
  doi: 10.1523/jneurosci.3547-03.2004
– volume: 30
  start-page: 1347
  issue: 12
  year: 2001
  end-page: 1356
  ident: CR128
  article-title: Methylmercury and H(2)O(2) provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis
  publication-title: Free Radical Biol Med
  doi: 10.1016/s0891-5849(01)00526-3
– volume: 30
  start-page: 1347
  issue: 12
  year: 2001
  ident: 2420_CR128
  publication-title: Free Radical Biol Med
  doi: 10.1016/s0891-5849(01)00526-3
– volume: 27
  start-page: 187
  issue: 1
  year: 2013
  ident: 2420_CR90
  publication-title: FASEB J
  doi: 10.1096/fj.12-208660
– volume: 79
  start-page: 545
  issue: 4
  year: 2005
  ident: 2420_CR24
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.20375
– volume: 17
  start-page: 171
  issue: 1
  year: 1997
  ident: 2420_CR135
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.17-01-00171.1997
– volume: 38
  start-page: 463
  issue: 5
  year: 2008
  ident: 2420_CR31
  publication-title: Crit Rev Toxicol
  doi: 10.1080/10408440802004023
– volume: 9
  start-page: 317
  issue: 3
  year: 1995
  ident: 2420_CR56
  publication-title: Toxicology in vitro : an international journal published in association with BIBRA
  doi: 10.1016/0887-2333(95)00002-p
– volume: 12
  start-page: 505
  issue: 3
  year: 1991
  ident: 2420_CR87
  publication-title: Neurotoxicology
– volume: 8
  start-page: e57898
  issue: 2
  year: 2013
  ident: 2420_CR97
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0057898
– volume: 914
  start-page: 159
  issue: 1–2
  year: 2001
  ident: 2420_CR117
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)02791-3
– volume: 69
  start-page: 436
  issue: 2
  year: 2021
  ident: 2420_CR148
  publication-title: Glia
  doi: 10.1002/glia.23908
– ident: 2420_CR16
  doi: 10.3390/nu11112585
– volume: 2018
  start-page: 7878050
  year: 2018
  ident: 2420_CR74
  publication-title: Oxid Med Cell Longev
  doi: 10.1155/2018/7878050
– volume: 741
  start-page: 52
  issue: 1–2
  year: 1996
  ident: 2420_CR102
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(96)00895-5
– volume: 79
  start-page: 48
  year: 2020
  ident: 2420_CR25
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2020.04.004
– volume: 60
  start-page: 212
  issue: 4
  year: 2009
  ident: 2420_CR12
  publication-title: Pharmacol Res
  doi: 10.1016/j.phrs.2009.02.011
– volume: 519
  start-page: 777
  issue: 4
  year: 2019
  ident: 2420_CR37
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2019.09.030
– volume: 107
  start-page: 1083
  issue: 4
  year: 2008
  ident: 2420_CR68
  publication-title: J Neurochem
  doi: 10.1111/j.1471-4159.2008.05683.x
– volume: 165
  start-page: 121
  issue: 2–3
  year: 2001
  ident: 2420_CR42
  publication-title: Toxicology
  doi: 10.1016/s0300-483x(01)00415-2
– volume: 908
  start-page: 149
  issue: 2
  year: 2001
  ident: 2420_CR130
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)02628-2
– volume: 14
  start-page: 724
  issue: 6
  year: 2011
  ident: 2420_CR132
  publication-title: Cell Metab
  doi: 10.1016/j.cmet.2011.08.016
– volume: 87
  start-page: 169
  issue: 1
  year: 2005
  ident: 2420_CR77
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfi227
– volume: 8
  start-page: e70163
  issue: 7
  year: 2013
  ident: 2420_CR114
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0070163
– volume: 118
  start-page: 1137
  issue: 8
  year: 2010
  ident: 2420_CR6
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.0901757
– volume: 74
  start-page: 112
  issue: 1
  year: 2008
  ident: 2420_CR73
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2008.09.019
– ident: 2420_CR52
  doi: 10.3390/ijms17071121
– volume: 530
  start-page: 245
  issue: 2
  year: 1990
  ident: 2420_CR69
  publication-title: Brain Res
  doi: 10.1016/0006-8993(90)91290-w
– volume: 106
  start-page: 1
  issue: 1–2
  year: 2002
  ident: 2420_CR144
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/S0169-328X(02)00403-5
– volume: 150
  start-page: 98
  issue: 1
  year: 1998
  ident: 2420_CR18
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1006/taap.1998.8383
– volume: 22
  start-page: 586
  issue: 6
  year: 2016
  ident: 2420_CR92
  publication-title: Nat Med
  doi: 10.1038/nm.4106
– volume: 47
  start-page: 1525
  issue: 9
  year: 1994
  ident: 2420_CR106
  publication-title: Biochem Pharmacol
  doi: 10.1016/0006-2952(94)90527-4
– volume: 758
  start-page: 253
  year: 2011
  ident: 2420_CR49
  publication-title: Methods Mol Biol
  doi: 10.1007/978-1-61779-170-3_17
– ident: 2420_CR8
  doi: 10.3390/ijerph14010074
– volume: 8
  start-page: 85
  issue: 1
  year: 1989
  ident: 2420_CR143
  publication-title: J Am Coll Toxicol
  doi: 10.3109/10915818909009095
– volume: 89
  start-page: 555
  issue: 15–16
  year: 2011
  ident: 2420_CR22
  publication-title: Life Sci
  doi: 10.1016/j.lfs.2011.05.019
– volume: 75
  start-page: 1091
  issue: 16–17
  year: 2012
  ident: 2420_CR30
  publication-title: J Toxicol Environ Health A
  doi: 10.1080/15287394.2012.697840
– volume: 40
  start-page: 199
  issue: 1
  year: 2015
  ident: 2420_CR38
  publication-title: Environ Toxicol Pharmacol
  doi: 10.1016/j.etap.2015.06.010
– volume: 118
  start-page: 331
  year: 2020
  ident: 2420_CR34
  publication-title: Neurosci Biobehav Rev
  doi: 10.1016/j.neubiorev.2020.07.039
– volume: 59
  start-page: 810
  issue: 5
  year: 2011
  ident: 2420_CR101
  publication-title: Glia
  doi: 10.1002/glia.21153
– volume: 74
  start-page: 196
  issue: 4–5
  year: 2000
  ident: 2420_CR142
  publication-title: Arch Toxicol
  doi: 10.1007/s002040000112
– volume: 521
  start-page: 221
  issue: 1–2
  year: 1990
  ident: 2420_CR67
  publication-title: Brain Res
  doi: 10.1016/0006-8993(90)91546-s
– volume: 17
  start-page: 663
  issue: 3–4
  year: 1996
  ident: 2420_CR32
  publication-title: Neurotoxicology
– volume: 51
  start-page: 19
  year: 2019
  ident: 2420_CR63
  publication-title: J Trace Elem Med Biol
  doi: 10.1016/j.jtemb.2018.09.004
– volume: 36
  start-page: 609
  issue: 8
  year: 2006
  ident: 2420_CR5
  publication-title: Crit Rev Toxicol
  doi: 10.1080/10408440600845619
– volume: 125
  start-page: 209
  issue: 1
  year: 2012
  ident: 2420_CR105
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfr252
– volume: 14
  start-page: e0218415
  issue: 6
  year: 2019
  ident: 2420_CR133
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0218415
– volume: 392
  start-page: 69
  issue: 1
  year: 2008
  ident: 2420_CR7
  publication-title: Sci Total Environ
  doi: 10.1016/j.scitotenv.2007.11.025
– volume: 66
  start-page: 998
  issue: 5
  year: 2001
  ident: 2420_CR118
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.10066
– volume: 146
  start-page: 106223
  year: 2021
  ident: 2420_CR2
  publication-title: Environ Int
  doi: 10.1016/j.envint.2020.106223
– volume: 9
  start-page: e98161
  issue: 5
  year: 2014
  ident: 2420_CR47
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0098161
– volume: 11
  start-page: 390
  issue: 2
  year: 2019
  ident: 2420_CR62
  publication-title: Metallomics
  doi: 10.1039/c8mt00297e
– volume: 68
  start-page: 151
  year: 2018
  ident: 2420_CR86
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2018.07.018
– ident: 2420_CR54
  doi: 10.3390/antiox6030062
– volume: 2018
  start-page: 6501031
  year: 2018
  ident: 2420_CR88
  publication-title: Oxid Med Cell Longev
  doi: 10.1155/2018/6501031
– volume: 32
  start-page: 291
  issue: 3
  year: 2011
  ident: 2420_CR126
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2011.01.004
– volume: 55
  start-page: 136
  issue: 1–3
  year: 2009
  ident: 2420_CR96
  publication-title: Neurochem Int
  doi: 10.1016/j.neuint.2009.01.015
– volume: 208
  start-page: 111686
  year: 2021
  ident: 2420_CR1
  publication-title: Ecotoxicol Environ Saf
  doi: 10.1016/j.ecoenv.2020.111686
– volume: 1
  start-page: 32
  issue: 1
  year: 2012
  ident: 2420_CR13
  publication-title: Toxicology research
  doi: 10.1039/C2TX20010D
– volume: 37
  start-page: 43
  issue: 1
  year: 2002
  ident: 2420_CR39
  publication-title: Glia
  doi: 10.1002/glia.10019
– volume: 92
  start-page: 95
  issue: 1
  year: 2014
  ident: 2420_CR46
  publication-title: J Neurosci Res
  doi: 10.1002/jnr.23290
– ident: 2420_CR48
  doi: 10.3390/ijms20020309
– volume: 32
  start-page: 200
  year: 2015
  ident: 2420_CR80
  publication-title: J Trace Elem Med Biol
  doi: 10.1016/j.jtemb.2015.06.008
– volume: 110
  start-page: 85
  issue: 1
  year: 2003
  ident: 2420_CR43
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/s0169-328x(02)00642-3
– volume: 25
  start-page: 849
  issue: 5
  year: 2004
  ident: 2420_CR123
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2004.01.005
– volume: 30
  start-page: 1000
  issue: 6
  year: 2009
  ident: 2420_CR59
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2009.08.001
– volume: 80
  start-page: 451
  issue: 3
  year: 1975
  ident: 2420_CR55
  publication-title: Am J Pathol
– volume: 602
  start-page: 181
  issue: 2
  year: 1993
  ident: 2420_CR115
  publication-title: Brain Res
  doi: 10.1016/0006-8993(93)90680-l
– volume: 107
  start-page: 135
  issue: 1
  year: 2009
  ident: 2420_CR109
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfn201
– volume: 54
  start-page: 5752
  issue: 8
  year: 2017
  ident: 2420_CR81
  publication-title: Mol Neurobiol
  doi: 10.1007/s12035-016-0101-2
– volume: 363
  start-page: 645
  issue: 3
  year: 2007
  ident: 2420_CR108
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2007.09.017
– volume: 33
  start-page: 141
  issue: 2
  year: 2007
  ident: 2420_CR9
  publication-title: Environ Int
  doi: 10.1016/j.envint.2006.08.005
– volume: 98
  start-page: 239
  issue: 1
  year: 2018
  ident: 2420_CR40
  publication-title: Physiol Rev
  doi: 10.1152/physrev.00042.2016
– volume: 59
  start-page: 197
  year: 2017
  ident: 2420_CR20
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2016.05.018
– volume: 1
  start-page: 529
  issue: 6
  year: 2001
  ident: 2420_CR17
  publication-title: Curr Top Med Chem
  doi: 10.2174/1568026013394831
– volume: 22
  start-page: 577
  issue: 5
  year: 2001
  ident: 2420_CR71
  publication-title: Neurotoxicology
  doi: 10.1016/s0161-813x(01)00050-x
– volume: 41
  start-page: 758
  issue: 9
  year: 2020
  ident: 2420_CR45
  publication-title: Trends Immunol
  doi: 10.1016/j.it.2020.07.004
– volume: 309
  start-page: 23
  year: 2018
  ident: 2420_CR129
  publication-title: Exp Neurol
  doi: 10.1016/j.expneurol.2018.07.009
– volume: 38
  start-page: 837
  issue: 6
  year: 2013
  ident: 2420_CR141
  publication-title: J Toxicol Sci
  doi: 10.2131/jts.38.837
– ident: 2420_CR131
  doi: 10.1042/BSR20180157
– volume: 37
  start-page: 1275
  issue: 6
  year: 2012
  ident: 2420_CR104
  publication-title: J Toxicol Sci
  doi: 10.2131/jts.37.1275
– volume: 14
  start-page: 99
  issue: 1
  year: 2017
  ident: 2420_CR36
  publication-title: J Neuroinflammation
  doi: 10.1186/s12974-017-0871-0
– volume: 108
  start-page: 334
  issue: 3
  year: 2008
  ident: 2420_CR28
  publication-title: Environ Res
  doi: 10.1016/j.envres.2008.06.006
– volume: 563
  start-page: 97
  issue: 2
  year: 2004
  ident: 2420_CR21
  publication-title: Mutat Res
  doi: 10.1016/j.mrgentox.2004.06.009
– volume: 37
  start-page: 136
  issue: 1
  year: 2011
  ident: 2420_CR11
  publication-title: Environ Int
  doi: 10.1016/j.envint.2010.08.009
– ident: 2420_CR50
  doi: 10.3390/cells8020184
– volume: 3
  start-page: 63
  issue: 2
  year: 2016
  ident: 2420_CR110
  publication-title: Fundam Toxicol Sci
  doi: 10.2131/fts.3.63
– volume: 23
  start-page: 755
  issue: 6
  year: 2002
  ident: 2420_CR122
  publication-title: Neurotoxicology
  doi: 10.1016/S0161-813X(01)00076-6
– volume: 36
  start-page: 463
  issue: 6
  year: 2017
  ident: 2420_CR99
  publication-title: Int J Toxicol
  doi: 10.1177/1091581817739428
– volume: 18
  start-page: 267
  year: 2017
  ident: 2420_CR15
  publication-title: Adv Neurobiol
  doi: 10.1007/978-3-319-60189-2_13
– volume: 128
  start-page: 48
  issue: 1
  year: 2004
  ident: 2420_CR124
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/j.molbrainres.2004.05.022
– volume: 4
  start-page: 4329
  year: 2014
  ident: 2420_CR98
  publication-title: Sci Rep
  doi: 10.1038/srep04329
– volume: 37
  start-page: 199
  issue: 2–3
  year: 2000
  ident: 2420_CR119
  publication-title: Neurochem Int
  doi: 10.1016/s0197-0186(00)00023-1
– ident: 2420_CR145
  doi: 10.1155/2010/656481
– volume: 4
  start-page: e2019GH000222
  issue: 5
  year: 2020
  ident: 2420_CR26
  publication-title: GeoHealth
  doi: 10.1029/2019gh000222
– volume: 27
  start-page: 1793
  issue: 10
  year: 2010
  ident: 2420_CR138
  publication-title: J Neurotrauma
  doi: 10.1089/neu.2010.1351
– volume: 11
  start-page: 125
  year: 2018
  ident: 2420_CR75
  publication-title: Front Mol Neurosci
  doi: 10.3389/fnmol.2018.00125
– ident: 2420_CR147
  doi: 10.3389/conf.fphar.2010.02.00011
– ident: 2420_CR53
  doi: 10.3390/antiox6030065
– year: 2019
  ident: 2420_CR41
  publication-title: Neurochem Res
  doi: 10.1007/s11064-019-02881-7
– volume: 24
  start-page: 324
  issue: 6
  year: 2013
  ident: 2420_CR134
  publication-title: Neuroreport
  doi: 10.1097/WNR.0b013e32835fc827
– volume: 19
  start-page: 249
  issue: 2
  year: 2005
  ident: 2420_CR83
  publication-title: Environ Toxicol Pharmacol
  doi: 10.1016/j.etap.2004.07.008
– volume: 53
  start-page: 361
  issue: 3
  year: 1998
  ident: 2420_CR100
  publication-title: J Neurosci Res
  doi: 10.1002/(SICI)1097-4547(19980801)53:3<361::AID-JNR10>3.0.CO;2-8
– volume: 256
  start-page: 405
  issue: 3
  year: 2011
  ident: 2420_CR14
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2011.05.001
– volume: 92
  start-page: 513
  issue: 1
  year: 2018
  ident: 2420_CR61
  publication-title: Arch Toxicol
  doi: 10.1007/s00204-017-2042-6
– volume: 902
  start-page: 92
  issue: 1
  year: 2001
  ident: 2420_CR121
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)02375-7
– volume: 125
  start-page: 300
  year: 2019
  ident: 2420_CR4
  publication-title: Environ Int
  doi: 10.1016/j.envint.2018.12.016
– volume: 1752
  start-page: 147234
  year: 2021
  ident: 2420_CR33
  publication-title: Brain Res
  doi: 10.1016/j.brainres.2020.147234
– volume: 119
  start-page: 1117
  issue: 8
  year: 2011
  ident: 2420_CR111
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1003123
– volume: 120
  start-page: 799
  issue: 6
  year: 2012
  ident: 2420_CR27
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1104494
– ident: 2420_CR35
  doi: 10.1093/function/zqaa016
– volume: 52
  start-page: 32
  issue: 1
  year: 2014
  ident: 2420_CR85
  publication-title: Clin Toxicol (Phila)
  doi: 10.3109/15563650.2013.860986
– volume: 53
  start-page: 2995
  issue: 5
  year: 2016
  ident: 2420_CR112
  publication-title: Mol Neurobiol
  doi: 10.1007/s12035-015-9161-y
– volume: 22
  start-page: 1877
  issue: 11
  year: 2015
  ident: 2420_CR113
  publication-title: Cell Death Differ
  doi: 10.1038/cdd.2015.49
– volume: 27
  start-page: 492
  issue: 4
  year: 2006
  ident: 2420_CR127
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2006.01.010
– volume: 113
  start-page: 328
  year: 2018
  ident: 2420_CR146
  publication-title: Food Chem
  doi: 10.1016/j.fct.2018.01.057
– volume: 242
  start-page: 109
  issue: 1
  year: 2010
  ident: 2420_CR19
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2009.09.022
– volume: 68
  start-page: 1017
  issue: 5
  year: 2020
  ident: 2420_CR89
  publication-title: Glia
  doi: 10.1002/glia.23759
– volume: 201
  start-page: 110799
  year: 2020
  ident: 2420_CR65
  publication-title: Ecotoxicol Environ Saf
  doi: 10.1016/j.ecoenv.2020.110799
– volume: 17
  start-page: 107
  issue: 1
  year: 1996
  ident: 2420_CR76
  publication-title: Neurotoxicology
– volume: 532
  start-page: 195
  issue: 7598
  year: 2016
  ident: 2420_CR95
  publication-title: Nature
  doi: 10.1038/nature17623
– volume: 284
  start-page: 161
  year: 2018
  ident: 2420_CR66
  publication-title: Toxicol Lett
  doi: 10.1016/j.toxlet.2017.12.006
– volume: 95
  start-page: 1
  issue: 1
  year: 2003
  ident: 2420_CR44
  publication-title: Biol Trace Elem Res
  doi: 10.1385/BTER:95:1:1
– volume: 24
  start-page: 2143
  issue: 9
  year: 2004
  ident: 2420_CR94
  publication-title: J Neurosci
  doi: 10.1523/jneurosci.3547-03.2004
– volume: 11
  start-page: e0162822
  issue: 9
  year: 2016
  ident: 2420_CR10
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0162822
– ident: 2420_CR51
  doi: 10.3390/ijms20030571
– volume: 83
  start-page: 113
  issue: 1
  year: 1994
  ident: 2420_CR103
  publication-title: Blood
  doi: 10.1182/blood.V83.1.113.113
– volume: 74
  start-page: 358
  year: 2016
  ident: 2420_CR29
  publication-title: Cortex
  doi: 10.1016/j.cortex.2015.05.017
– volume: 12
  start-page: e0170623
  issue: 1
  year: 2017
  ident: 2420_CR140
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0170623
– volume: 38
  start-page: 124
  year: 2017
  ident: 2420_CR57
  publication-title: Toxicol In Vitro
  doi: 10.1016/j.tiv.2016.10.001
– volume: 93
  start-page: 1543
  issue: 4
  year: 2013
  ident: 2420_CR136
  publication-title: Physiol Rev
  doi: 10.1152/physrev.00011.2013
– volume: 37
  start-page: 749
  issue: 4
  year: 2012
  ident: 2420_CR137
  publication-title: J Toxicol Sci
  doi: 10.2131/jts.37.749
– volume: 93
  start-page: 12
  issue: 1
  year: 2009
  ident: 2420_CR72
  publication-title: Microchem J
  doi: 10.1016/j.microc.2009.03.008
– volume: 126
  start-page: 106001
  issue: 10
  year: 2018
  ident: 2420_CR3
  publication-title: Environ Health Perspect
  doi: 10.1289/EHP3904
– volume: 494
  start-page: 90
  issue: 7435
  year: 2012
  ident: 2420_CR93
  publication-title: Nature
  doi: 10.1038/nature11748
– volume: 41
  start-page: 819
  issue: 7
  year: 2001
  ident: 2420_CR23
  publication-title: Neuropharmacology
  doi: 10.1016/s0028-3908(01)00130-7
– volume: 25
  start-page: 771
  issue: 5
  year: 2004
  ident: 2420_CR84
  publication-title: Neurotoxicology
  doi: 10.1016/j.neuro.2004.03.001
– ident: 2420_CR139
  doi: 10.3390/ijms20102435
– volume: 17
  start-page: 17
  issue: 1
  year: 1996
  ident: 2420_CR125
  publication-title: Neurotoxicology
– volume: 9
  start-page: 12860
  issue: 1
  year: 2019
  ident: 2420_CR70
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-49009-z
– volume: 17
  start-page: 531
  issue: 2
  year: 1996
  ident: 2420_CR82
  publication-title: Neurotoxicology
– volume: 129
  start-page: 196
  issue: 2
  year: 1994
  ident: 2420_CR64
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1006/taap.1994.1244
– volume: 35
  start-page: 285
  issue: 3
  year: 2008
  ident: 2420_CR58
  publication-title: J Chem Neuroanat
  doi: 10.1016/j.jchemneu.2008.01.003
– volume: 137
  start-page: 11
  issue: 1–2
  year: 2005
  ident: 2420_CR107
  publication-title: Brain Res Mol Brain Res
  doi: 10.1016/j.molbrainres.2005.02.006
– volume: 22
  start-page: 317
  issue: 3
  year: 2001
  ident: 2420_CR79
  publication-title: Neurotoxicology
  doi: 10.1016/s0161-813x(01)00015-8
– volume: 9
  start-page: 13899
  issue: 1
  year: 2019
  ident: 2420_CR60
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-50377-9
– volume: 107
  start-page: 231
  issue: 3
  year: 2005
  ident: 2420_CR120
  publication-title: Biol Trace Elem Res
  doi: 10.1385/BTER:107:3:231
– volume: 894
  start-page: 131
  issue: 1
  year: 2001
  ident: 2420_CR116
  publication-title: Brain Res
  doi: 10.1016/s0006-8993(01)01988-6
– volume: 57
  start-page: 96
  year: 2019
  ident: 2420_CR78
  publication-title: Toxicol In Vitro
  doi: 10.1016/j.tiv.2019.02.013
– ident: 2420_CR91
  doi: 10.3389/fnmol.2017.00088
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Snippet Intoxication by heavy metals such as methylmercury (MeHg) is recognized as a global health problem, with strong implications in central nervous system...
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SubjectTerms Astrocytes
Astrocytes - drug effects
Astrocytes - pathology
Biomedical and Life Sciences
Biomedicine
Brain - drug effects
Brain - pathology
Brain injury
Cell Biology
Central nervous system
Dimethylmercury
Glial cells
Heavy metals
Homeostasis
Humans
Intoxication
Memory
Methylmercury Compounds - toxicity
Neurobiology
Neurology
Neuromodulation
Neurons
Neurons - drug effects
Neurons - pathology
Neurosciences
Neurotoxicity
Neurotoxicity Syndromes - pathology
Public health
Roles
Visual discrimination learning
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Title Revisiting Astrocytic Roles in Methylmercury Intoxication
URI https://link.springer.com/article/10.1007/s12035-021-02420-y
https://www.ncbi.nlm.nih.gov/pubmed/33990914
https://www.proquest.com/docview/2578529895
https://www.proquest.com/docview/2528178162
Volume 58
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