Impairment of the class IIa bacteriocin receptor function and membrane structural changes are associated to enterocin CRL35 high resistance in Listeria monocytogenes

• Published in: Biochimica et biophysica acta. General subjects Vol. 1861; no. 7; pp. 1770 - 1776
• Main Authors: Masias, Emilse, Dupuy, Fernando G., da Silva Sanches, Paulo Ricardo, Farizano, Juan Vicente, Cilli, Eduardo, Bellomio, Augusto, Saavedra, Lucila, Minahk, Carlos
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2017
• Subjects: antibacterial properties; bacteria; Bacteriocins; Bacteriocins - metabolism; Bacteriocins - pharmacology; Cell Membrane - chemistry; cell walls; culture media; Drug Resistance, Bacterial; Enterocin CRL35; Fourier transform infrared spectroscopy; glucose; Glucose - metabolism; hydrophobicity; lipids; Listeria; Listeria monocytogenes; Listeria monocytogenes - drug effects; Listeria monocytogenes - growth & development; Membrane Lipids - analysis; microbial growth; Microbial Sensitivity Tests; peptides; plasma membrane; polymerase chain reaction; RNA; sequence analysis; Synthetic peptides; Synthetic peptides; Listeria; Bacteriocins; Enterocin CRL35

Enterocin CRL35 is a class IIa bacteriocin with anti-Listeria activity. Resistance to these peptides has been associated with either the downregulation of the receptor expression or changes in the membrane and cell walls. The scope of the present work was to characterize enterocin CRL35 resistant Li...