ARFI, FibroScan®, ELF, and their combinations in the assessment of liver fibrosis: A prospective study

• Published in: Journal of hepatology Vol. 57; no. 2; pp. 281 - 287
• Main Authors: Crespo, Gonzalo, Fernández-Varo, Guillermo, Mariño, Zoe, Casals, Gregori, Miquel, Rosa, Martínez, Stella M, Gilabert, Rosa, Forns, Xavier, Jiménez, Wladimiro, Navasa, Miquel
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.08.2012; Elsevier
• Subjects: Acoustic radiation force impulse; Adult; Aged; Biological and medical sciences; Biopsy; Elasticity Imaging Techniques - methods; Enhanced liver fibrosis; Female; Gastroenterology and Hepatology; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Liver - pathology; Liver Cirrhosis - diagnosis; Liver Transplantation; Liver, biliary tract, pancreas, portal circulation, spleen; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Middle Aged; Other diseases. Semiology; Prospective Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Transient elastography; shear wave velocity; positive predictive value; TIMP-1; LR; transient elastography; LT; AUROC; aminoterminal propeptide of type III procollagen; hyaluronic acid; SD; diagnostic odds ratio; NPV; PPV; specificity; area under the receiver-operating characteristic curve; interquantile range; variation coefficient; BMI; liver stiffness measurement; tissue inhibitor of matrix metalloproteinase type-1; body mass index; DOR; LSM; ARFI; IQR; ROI; VC; likelihood ratio negative; TE; PIIINP; enhanced liver fibrosis; Se; SWV; region of interest; HA; sensitivity; kilopascals; kPa; Sp; ELF; liver transplantation; negative predictive value; likelihood ratio positive; acoustic radiation force impulse; standard deviation; Transient elastography; Acoustic radiation force impulse; Enhanced liver fibrosis; Liver transplantation; Hepatic fibrosis; Gastroenterology; Medical imagery; Digestive diseases; Hepatic disease; Impulse

Background & Aims Our aim was to evaluate a serologic marker (ELF) and two ultrasound-based methods (FibroScan® and ARFI), as well as their combinations, in the assessment of liver fibrosis. Methods One-hundred and forty-six patients (87 liver transplant recipients, 59 non-transplant patients) w...