Interpretation of differential gene expression results of RNA-seq data: review and integration

• Published in: Briefings in bioinformatics Vol. 20; no. 6; pp. 2044 - 2054
• Main Authors: McDermaid, Adam, Monier, Brandon, Zhao, Jing, Liu, Bingqiang, Ma, Qin
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 27.11.2019
• Subjects: bioinformatics; Computational Biology - methods; Gene Expression; gene expression regulation; High-Throughput Nucleotide Sequencing - methods; humans; Malus domestica; Review; sequence analysis; Sequence Analysis, RNA; Vitis riparia; differentially expressed genes; visualization and interpretation; differential gene expression analysis; bioinformatics tools; R/Bioconductor package

Abstract Differential gene expression (DGE) analysis is one of the most common applications of RNA-sequencing (RNA-seq) data. This process allows for the elucidation of differentially expressed genes across two or more conditions and is widely used in many applications of RNA-seq data analysis. Inte...