Multilocus sequence typing of Dientamoeba fragilis identified a major clone with widespread geographical distribution

• Published in: International journal for parasitology Vol. 46; no. 12; pp. 793 - 798
• Main Authors: Cacciò, Simone M., Sannella, Anna Rosa, Bruno, Antonella, Stensvold, Christen R., David, Erica Boarato, Guimarães, Semiramis, Manuali, Elisabetta, Magistrali, Chiara, Mahdad, Karim, Beaman, Miles, Maserati, Roberta, Tosini, Fabio, Pozio, Edoardo
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.11.2016
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Australia; Brazil; Child; Child, Preschool; Denmark; Dientamoeba - classification; Dientamoeba - genetics; Dientamoeba fragilis; Dientamoebiasis - parasitology; DNA-directed RNA polymerase; feces; Feces - parasitology; Female; gastrointestinal system; Genetic Markers; Genetic Variation; genotype; Genotyping Techniques; geographical distribution; Human; Humans; Italy; loci; Male; metagenomics; Middle Aged; Multilocus genotyping; Multilocus Sequence Typing; parasites; people; Peptide Hydrolases - genetics; phylogeny; Polymerase Chain Reaction; Population structure; proteinases; ribosomal DNA; sequence homology; structural genes; Trichomonas vaginalis; Young Adult; Brazil; Denmark; Italy; Australia; Human; Multilocus genotyping; Population structure; Dientamoeba fragilis; Genetic markers

[Display omitted] •Development of markers for genotyping of Dientamoeba fragilis isolates is described.•Low levels of genetic variability exist among isolates from various parts of the world.•Genetic structure of the parasite population is likely to be clonal. The flagellated protozoan Dientamoeba f...