Methanogenic Flora Is Associated With Altered Colonic Transit but Not Stool Characteristics in Constipation Without IBS

• Published in: The American journal of gastroenterology Vol. 105; no. 6; pp. 1407 - 1411
• Main Authors: Attaluri, Ashok, Jackson, Michelle, Valestin, Jessica, Rao, Satish SC
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.06.2010; Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
• Subjects: Adult; Aged; Biological and medical sciences; Colon - microbiology; Colon - physiopathology; Constipation - microbiology; Constipation - physiopathology; Feces - microbiology; Gastroenterology; Gastroenterology. Liver. Pancreas. Abdomen; Gastrointestinal Transit - physiology; Humans; Irritable Bowel Syndrome - microbiology; Irritable Bowel Syndrome - physiopathology; Male; Medical sciences; Methane - biosynthesis; Middle Aged; Other diseases. Semiology; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Young Adult; Characteristic; Gastroenterology; Digestive diseases; Intestinal disease; Colon; Feces; Constipation

About 35% of humans have methane-producing gut flora. Methane-producing irritable bowel syndrome (IBS) subjects are generally constipated. In animal models, methane infusion slows intestinal transit. Whether methanogenic flora alters colonic transit or stool characteristics and its relationship to c...