Bile acids and the gut microbiota: metabolic interactions and impacts on disease
Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensit...
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| Published in | Nature reviews. Microbiology Vol. 21; no. 4; pp. 236 - 247 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
London
Nature Publishing Group UK
01.04.2023
Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensitive, the repertoire of bile acids metabolized and/or synthesized by bacteria continues to grow. Additionally, bile acids impact microbiome community structure and function. In this Review, we highlight how the bile acid pool is manipulated by the gut microbiota, how it is dependent on the metabolic capacity of the bacterial community and how external factors, such as antibiotics and diet, shape bile acid composition. It is increasingly important to understand how bile acid signalling networks are affected in distinct organs where the bile acid composition differs, and how these networks impact infectious, metabolic and neoplastic diseases. These advances have enabled the development of therapeutics that target imbalances in microbiota-associated bile acid profiles.
The gut microbiota metabolizes bile acids, thereby influencing human health and diseases including obesity, colitis and cancer. In this Review, Patterson and colleagues discuss host–microbiota interactions and their influence on the bile acid pool as well as therapeutic implications. |
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| AbstractList | Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensitive, the repertoire of bile acids metabolized and/or synthesized by bacteria continues to grow. Additionally, bile acids impact microbiome community structure and function. In this Review, we highlight how the bile acid pool is manipulated by the gut microbiota, how it is dependent on the metabolic capacity of the bacterial community and how external factors, such as antibiotics and diet, shape bile acid composition. It is increasingly important to understand how bile acid signalling networks are affected in distinct organs where the bile acid composition differs, and how these networks impact infectious, metabolic and neoplastic diseases. These advances have enabled the development of therapeutics that target imbalances in microbiota-associated bile acid profiles.Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensitive, the repertoire of bile acids metabolized and/or synthesized by bacteria continues to grow. Additionally, bile acids impact microbiome community structure and function. In this Review, we highlight how the bile acid pool is manipulated by the gut microbiota, how it is dependent on the metabolic capacity of the bacterial community and how external factors, such as antibiotics and diet, shape bile acid composition. It is increasingly important to understand how bile acid signalling networks are affected in distinct organs where the bile acid composition differs, and how these networks impact infectious, metabolic and neoplastic diseases. These advances have enabled the development of therapeutics that target imbalances in microbiota-associated bile acid profiles. Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensitive, the repertoire of bile acids metabolized and/or synthesized by bacteria continues to grow. Additionally, bile acids impact microbiome community structure and function. In this Review, we highlight how the bile acid pool is manipulated by the gut microbiota, how it is dependent on the metabolic capacity of the bacterial community and how external factors, such as antibiotics and diet, shape bile acid composition. It is increasingly important to understand how bile acid signalling networks are affected in distinct organs where the bile acid composition differs, and how these networks impact infectious, metabolic and neoplastic diseases. These advances have enabled the development of therapeutics that target imbalances in microbiota-associated bile acid profiles.The gut microbiota metabolizes bile acids, thereby influencing human health and diseases including obesity, colitis and cancer. In this Review, Patterson and colleagues discuss host–microbiota interactions and their influence on the bile acid pool as well as therapeutic implications. Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensitive, the repertoire of bile acids metabolized and/or synthesized by bacteria continues to grow. Additionally, bile acids impact microbiome community structure and function. In this Review, we highlight how the bile acid pool is manipulated by the gut microbiota, how it is dependent on the metabolic capacity of the bacterial community and how external factors, such as antibiotics and diet, shape bile acid composition. It is increasingly important to understand how bile acid signalling networks are affected in distinct organs where the bile acid composition differs, and how these networks impact infectious, metabolic and neoplastic diseases. These advances have enabled the development of therapeutics that target imbalances in microbiota-associated bile acid profiles. The gut microbiota metabolizes bile acids, thereby influencing human health and diseases including obesity, colitis and cancer. In this Review, Patterson and colleagues discuss host–microbiota interactions and their influence on the bile acid pool as well as therapeutic implications. Despite decades of bile acid research, diverse biological roles for bile acids have been discovered recently due to developments in understanding the human microbiota. As additional bacterial enzymes are characterized, and the tools used for identifying new bile acids become increasingly more sensitive, the repertoire of bile acids metabolized and/or synthesized by bacteria continues to grow. Additionally, bile acids impact microbiome community structure and function. In this Review, we highlight how the bile acid pool is manipulated by the gut microbiota, how it is dependent on the metabolic capacity of the bacterial community and how external factors, such as antibiotics and diet, shape bile acid composition. It is increasingly important to understand how bile acid signalling networks are affected in distinct organs where the bile acid composition differs, and how these networks impact infectious, metabolic and neoplastic diseases. These advances have enabled the development of therapeutics that target imbalances in microbiota-associated bile acid profiles. |
| Author | Bisanz, Jordan E. Collins, Stephanie L. Okafor, C. Denise Patterson, Andrew D. Stine, Jonathan G. |
| Author_xml | – sequence: 1 givenname: Stephanie L. orcidid: 0000-0002-2773-646X surname: Collins fullname: Collins, Stephanie L. organization: Department of Biochemistry and Molecular Biology, The Pennsylvania State University – sequence: 2 givenname: Jonathan G. surname: Stine fullname: Stine, Jonathan G. organization: Division of Gastroenterology and Hepatology, Department of Medicine, Penn State Health Milton S. Hershey Medical Center, Department of Public Health Sciences, Penn State Health Milton S. Hershey Medical Center, Penn State Health Liver Center, Penn State Health Milton S. Hershey Medical Center, Penn State Cancer Institute, Penn State Health Milton S. Hershey Medical Center – sequence: 3 givenname: Jordan E. surname: Bisanz fullname: Bisanz, Jordan E. organization: Department of Biochemistry and Molecular Biology, The Pennsylvania State University – sequence: 4 givenname: C. Denise surname: Okafor fullname: Okafor, C. Denise organization: Department of Biochemistry and Molecular Biology, The Pennsylvania State University, Department of Chemistry, The Pennsylvania State University – sequence: 5 givenname: Andrew D. orcidid: 0000-0003-2073-0070 surname: Patterson fullname: Patterson, Andrew D. email: adp117@psu.edu organization: Department of Biochemistry and Molecular Biology, The Pennsylvania State University, Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/36253479$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1073/pnas.0409794102 10.1016/S0304-3835(01)00786-8 10.1038/nature04330 10.1002/ijc.26293 10.1056/NEJMoa1509840 10.1016/j.atherosclerosis.2011.06.040 10.1016/j.celrep.2014.02.032 10.1016/j.cmet.2017.09.008 10.1007/s11095-013-0986-7 10.1128/AAC.01664-10 10.1093/carcin/23.5.885 10.1126/science.1179721 10.1152/ajpgi.00167.2011 10.1194/jlr.M072819 10.1038/nature13828 10.3389/fmicb.2017.01581 10.1136/gutjnl-2017-314307 10.1016/S0092-8674(00)00062-3 10.1016/S1097-2765(00)00050-2 10.1038/s41598-019-48784-z 10.1128/mSystems.00805-21 10.1038/s41591-019-0504-5 10.1371/journal.pone.0022978 10.1038/nature12503 10.1016/j.chembiol.2018.10.003 10.1128/aem.44.5.1030-1034.1982 10.1016/j.cmet.2005.09.001 10.1177/0148607190014002183 10.1038/ejcn.2012.126 10.1038/s41467-020-17183-8 10.18632/oncotarget.17188 10.1126/science.284.5418.1362 10.1101/gad.1083503 10.1124/mol.65.2.292 10.1038/nature06244 10.1152/ajpgi.00027.2007 10.1038/s41587-021-01045-9 10.1097/MOG.0000000000000057 10.1038/nchembio.1864 10.1126/science.1070477 10.1038/nature05414 10.1016/j.ccr.2012.02.007 10.1016/j.cgh.2020.08.063 10.1074/jbc.M110.116004 10.1126/science.284.5418.1365 10.1136/gutjnl-2015-310283 10.1016/j.molmed.2021.12.006 10.1124/jpet.108.145409 10.1172/JCI21025 10.1038/nrd2619 10.1080/19490976.2020.1732268 10.1016/j.chom.2014.02.005 10.1056/NEJMoa1205037 10.1016/j.febslet.2014.09.039 10.1126/science.aad3503 10.1016/S0006-291X(02)02550-0 10.1038/nature13135 10.1016/j.anaerobe.2017.03.004 10.1186/s40168-019-0689-3 10.2741/3399 10.1074/jbc.M411520200 10.1128/aem.62.2.656-661.1996 10.1136/gutjnl-2012-302578 10.1080/19490976.2016.1150414 10.1038/s41564-018-0306-4 10.1016/j.cmet.2009.08.001 10.1194/jlr.RA120001021 10.21203/rs.3.rs-820302/v1 10.1073/pnas.0509592103 10.1038/s41586-020-2047-9 10.1073/pnas.0506982103 10.1016/j.bbadis.2011.04.005 10.1073/pnas.1903316116 10.1073/pnas.2017709118 10.1016/j.bbadis.2018.05.011 10.1016/0022-4731(86)90429-2 10.1194/jlr.R054114 10.2147/CEG.S4343 10.1021/acschembio.1c00192 10.1038/s41586-022-04480-z 10.1038/s41586-021-03663-4 10.1016/j.mrrev.2004.08.001 10.1053/jhep.2003.50311 10.3389/fpsyt.2020.00518 10.1038/srep38089 10.1053/j.gastro.2018.12.001 10.1038/s41586-020-2396-4 10.1194/jlr.RA119000395 10.1128/mBio.01541-16 10.4049/jimmunol.0803978 10.1038/s41575-021-00566-7 10.1038/s41586-019-1785-z 10.1074/jbc.M209706200 10.1016/S0140-6736(14)61933-4 10.1074/jbc.M510713200 10.1053/j.gastro.2012.06.031 10.1073/pnas.051551698 10.1038/sigtrans.2017.23 10.1128/AEM.66.6.2502-2512.2000 10.1073/pnas.212494599 10.1038/sj.ejcn.1602607 10.1074/jbc.M111.248203 10.1016/j.cell.2010.01.025 10.1073/pnas.1916965117 10.1016/j.chom.2019.06.013 10.1038/nrgastro.2017.119 10.1111/j.1572-0241.2005.41794.x 10.1016/j.ejphar.2011.06.058 10.1136/gutjnl-2018-317842 10.1016/j.autrev.2017.07.002 10.1152/ajpgi.00528.2006 10.1002/hep.24525 10.1016/0039-128X(80)90115-4 10.1002/cam4.1965 10.1136/gut.2010.212159 10.3892/etm.2021.10423 10.1016/j.anaerobe.2018.04.001 10.1038/s41598-018-19545-1 10.1073/pnas.0706736104 10.1016/j.jhep.2013.11.034 10.1053/j.gastro.2013.05.042 10.1016/S1097-2765(00)00051-4 10.1038/s41586-019-1865-0 10.1016/j.cmet.2013.01.003 10.1152/ajpgi.00282.2013 10.1016/j.femsre.2004.09.003 10.1124/jpet.111.179390 10.1016/j.tem.2017.11.002 10.1038/sj.ejcn.1600940 10.1186/s40168-021-01101-1 10.1038/s41598-020-58644-w 10.1038/4441022a 10.1038/nrmicro3344 10.1080/19490976.2020.1854008 10.1172/JCI126905 10.1038/s41467-021-23460-x 10.1074/jbc.M302128200 10.3389/fphar.2018.01382 10.7554/eLife.48431 10.1111/eci.12958 10.1158/1055-9965.EPI-08-1187 10.1002/ijc.30219 10.1073/pnas.0913554107 10.1002/hep.29857 10.1093/carcin/22.6.957 10.1158/0008-5472.CAN-06-1078 10.1016/j.bbrc.2005.01.139 10.1038/s41587-019-0375-9 10.1152/ajpgi.00046.2020 10.1128/aem.54.8.2112-2117.1988 10.1016/0022-4731(84)90404-7 10.1053/j.gastro.2012.09.055 10.1073/pnas.1006734107 10.1038/s41598-020-75162-x 10.1136/gut.2005.073817 10.1093/jnci/dji144 10.1016/j.celrep.2018.12.028 10.1073/pnas.0804812105 10.1038/s41419-020-02819-w 10.1038/s41420-021-00589-8 10.1038/s41586-019-1237-9 10.1073/pnas.1323599111 10.1161/CIRCULATIONAHA.109.192644 10.1038/nature12347 10.1186/s40168-018-0557-6 10.1128/JB.01765-07 10.1038/145627a0 10.1056/NEJMoa0910812 10.1002/jat.3644 10.1016/j.drugalcdep.2008.08.001 10.1128/mSphere.00045-15 10.1016/j.cmet.2016.05.005 10.1016/j.clnu.2019.02.037 10.1038/nature18646 10.1128/jb.179.8.2512-2518.1997 10.1038/ncomms4114 10.1073/pnas.0407076101 10.1038/s41586-021-04126-6 10.1074/jbc.M405423200 10.1172/JCI130976 10.1194/jlr.R500013-JLR200 10.1073/pnas.0804437105 |
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| References | Qiao, Gaitonde, Qi, Martinez (CR117) 2001; 22 Parks (CR159) 1999; 284 Makishima (CR169) 2002; 296 Joyce (CR99) 2014; 111 Inagaki (CR54) 2006; 103 Jiao (CR94) 2018; 67 Maruyama (CR176) 2002; 298 Guzior, Quinn (CR10) 2021; 9 Pathak (CR97) 2018; 68 Makishima (CR158) 1999; 284 Antunes (CR29) 2011; 55 Lax (CR121) 2012; 130 Laidlaw, Grosvenor, Kopple (CR127) 1990; 14 Tam (CR65) 2020; 117 Katsuma, Hirasawa, Tsujimoto (CR95) 2005; 329 Korpela, Fotsis, Adlercreutz (CR22) 1986; 25 Wang (CR151) 2019; 26 Stedman (CR167) 2005; 102 Funabashi (CR16) 2020; 582 Franzosa (CR69) 2019; 4 Xiao (CR82) 2016; 6 Ellegård, Bosaeus, Andersson (CR43) 2000; 54 Meissner (CR37) 2011; 218 Reissig, Strain, Griffiths (CR128) 2009; 99 Kuno, Hirayama-Kurogi, Ito, Ohtsuki (CR33) 2018; 8 Danese (CR39) 2017; 8 Mencarelli (CR77) 2011; 668 Shah, Ma, Morimura, Kim, Gonzalez (CR79) 2007; 292 Maran (CR122) 2009; 328 Vrieze (CR32) 2014; 60 Manichanh (CR70) 2006; 55 Ryan (CR100) 2014; 509 Yoshimoto (CR114) 2013; 499 Payne, Bernstein, Dvorak, Bernstein (CR118) 2008; 1 Appleyard (CR139) 2011; 301 Theriot (CR31) 2014; 5 Walters, Xu, Knight (CR91) 2014; 588 Ley, Turnbaugh, Klein, Gordon (CR89) 2006; 444 Bisanz, Upadhyay, Turnbaugh, Ly, Turnbaugh (CR92) 2019; 26 Cao (CR184) 2021; 600 Li, Dawson (CR8) 2019; 1865 Gevers (CR71) 2014; 15 Ridlon, Wolf, Gaskins (CR126) 2016; 7 Begley, Gahan, Hill (CR50) 2005; 29 Qian (CR68) 2020; 319 Duboc (CR72) 2013; 62 Kawamata (CR177) 2003; 278 Ðanić (CR101) 2018; 9 Heinken (CR75) 2019; 7 Kazemian (CR135) 2020; 10 Rea (CR57) 2010; 107 Paramsothy (CR132) 2019; 156 Inagaki (CR160) 2005; 2 Staudinger (CR171) 2001; 98 Sayin (CR155) 2013; 17 McCarthy, Li, Sinal (CR172) 2005; 280 Wahlström, Sayin, Marschall, Bäckhed (CR19) 2016; 24 Yang (CR123) 2007; 67 Washo-Stultz (CR119) 2002; 177 Marion (CR18) 2020; 61 Yu (CR120) 2020; 11 Eldere, Celis, Pauw, Lesaffre, Eyssen (CR12) 1996; 62 Lucas (CR28) 2021 Turnbaugh (CR1) 2007; 449 Molinaro, Wahlström, Marschall (CR157) 2018; 29 Seekatz (CR130) 2018; 53 Meixiong, Vasavda, Snyder, Dong (CR182) 2019; 116 Zhang (CR106) 2006; 103 Holt (CR161) 2003; 17 Molina-Molina (CR35) 2018; 48 Sonoda (CR170) 2002; 99 Neuschwander-Tetri (CR104) 2015; 385 Wang, Chen, Yu, Forman, Huang (CR178) 2011; 54 Kootte (CR85) 2017; 26 Zhao (CR133) 2020; 130 Wolfe (CR124) 2011; 338 Parséus (CR105) 2017; 66 Watanabe (CR98) 2004; 113 Dapito (CR113) 2012; 21 Wan (CR41) 2020; 39 Nevens (CR152) 2016; 375 Sannasiddappa, Lund, Clarke (CR48) 2017; 8 Hang (CR146) 2019; 576 Theriot, Bowman, Young (CR59) 2016; 1 Cook, Kennaway, Kennaway (CR110) 1940; 145 Hofmann (CR5) 2009; 14 He (CR88) 2018; 6 Buffie (CR63) 2015; 517 Streidl (CR17) 2021; 13 Liu, Zhang, Joo, Sun (CR53) 2017; 2 Jones, Martoni, Prakash (CR140) 2012; 66 Foley (CR11) 2021; 118 Weingarden (CR66) 2014; 306 Alberti (CR81) 2009; 120 Hoffmann (CR25) 2022; 40 Jones, Begley, Hill, Gahan, Marchesi (CR4) 2008; 105 White, Lipsky, Fricke, Hylemon (CR15) 1980; 35 Song (CR149) 2020; 577 Tanaka, Hashiba, Kok, Mierau (CR13) 2000; 66 Watanabe (CR181) 2006; 439 Wahlström (CR7) 2017; 58 von Schwartzenberg (CR45) 2021; 595 Pearson (CR145) 2019; 8 Hamilton (CR3) 2007; 293 Pedersen (CR87) 2016; 535 Mudaliar (CR103) 2013; 145 Vijay-Kumar (CR93) 2010; 328 Watanabe (CR107) 2011; 286 van Nood (CR129) 2013; 368 Wertheim (CR38) 2009; 18 Grivennikov, Greten, Karin (CR116) 2010; 140 Mullish (CR131) 2019; 68 Gadaleta (CR78) 2011; 60 Swann (CR30) 2011; 108 Gadaleta (CR125) 2011; 1812 Zhang, Xu, Zhang, Tang, Bi (CR144) 2021; 7 Ca, Bj, Jb (CR36) 1993; 265 Dawson, Karpen (CR23) 2015; 56 Adhikari (CR147) 2021; 16 Quinn (CR24) 2020; 579 Miao, Fang, Bae, Kemper (CR175) 2006; 281 Xie (CR112) 2016; 139 Van Eldere, Robben, De Pauw, Merckx, Eyssen (CR21) 1988; 54 Tian (CR49) 2020; 11 Saini (CR168) 2004; 65 Thomas (CR180) 2009; 10 Louis, Hold, Flint (CR44) 2014; 12 Wilson, Almousa, Teft, Kim (CR80) 2020; 10 Ridlon, Kang, Hylemon (CR14) 2006; 47 Schmidt (CR173) 2010; 285 Ma, Huang, Yan, Gao, Liu (CR108) 2013; 30 Alberts (CR141) 2005; 97 Sinal (CR164) 2000; 102 Ellegård, Andersson (CR42) 2007; 61 Bhalla, Ozalp, Fang, Xiang, Kemper (CR174) 2004; 279 McGarr, Ridlon, Hylemon (CR111) 2005; 39 Bernstein, Bernstein, Payne, Dvorakova, Garewal (CR115) 2005; 589 Dethloff (CR34) 2020; 11 Bárcena (CR134) 2019; 25 Li, Tang, Leung, Gershwin, Ma (CR55) 2017; 16 Bibiloni (CR136) 2005; 100 Goodwin (CR162) 2000; 6 Paik (CR148) 2022; 603 Ng (CR58) 2013; 502 Turnbaugh (CR83) 2006; 444 Sanyal (CR165) 2007; 104 Thanassi, Cheng, Nikaido (CR52) 1997; 179 Lloyd-Price (CR74) 2019; 569 Devlin, Fischbach (CR20) 2015; 11 Jia, Xie, Jia (CR109) 2018; 15 Pircher (CR166) 2003; 278 Fuchs, Trauner (CR2) 2022 Serfaty (CR143) 2003; 38 Alemi (CR179) 2013; 144 Lu (CR163) 2000; 6 Wang (CR27) 2020; 38 Cabrera-Rubio, Patterson, Cotter, Beraza (CR56) 2019; 9 Bäckhed (CR84) 2004; 101 Huijghebaert, Eyssen (CR153) 1982; 44 Sokol (CR73) 2008; 105 Miller (CR51) 2016; 7 Kang (CR64) 2019; 26 Thomas, Pellicciari, Pruzanski, Auwerx, Schoonjans (CR96) 2008; 7 Falony (CR90) 2016; 352 Thakare, Alamoudi, Gautam, Rodrigues, Alnouti (CR6) 2018; 38 Yu (CR183) 2019; 8 Sorg, Sonenshein (CR61) 2008; 190 Louie (CR67) 2011; 364 Thibaut, Bindels (CR156) 2022; 28 Gentry (CR26) 2021 Robinson (CR60) 2019; 129 Vavassori, Mencarelli, Renga, Distrutti, Fiorucci (CR76) 2009; 183 Mencarelli (CR138) 2011; 6 van der Lelie (CR150) 2021; 12 Degirolamo, Rainaldi, Bovenga, Murzilli, Moschetta (CR137) 2014; 7 Thanissery, Winston, Theriot (CR62) 2017; 45 Ridlon, Kang, Hylemon, Bajaj (CR47) 2014; 30 Vrieze (CR86) 2012; 143 Zhang, Dong, Liu (CR102) 2021; 22 Huijghebaert, Parmentier, Eyssen (CR154) 1984; 20 Hughes (CR40) 2021; 19 van Best (CR46) 2020; 11 Oyama, Shiota, Ito, Murawaki, Kawasaki (CR142) 2002; 23 Honda (CR9) 2020; 61 H Sokol (805_CR73) 2008; 105 Y Li (805_CR55) 2017; 16 CG Buffie (805_CR63) 2015; 517 R Thanissery (805_CR62) 2017; 45 KM Ng (805_CR58) 2013; 502 A Mencarelli (805_CR138) 2011; 6 Y Wan (805_CR41) 2020; 39 DR Schmidt (805_CR173) 2010; 285 T Maruyama (805_CR176) 2002; 298 D van der Lelie (805_CR150) 2021; 12 HK Pedersen (805_CR87) 2016; 535 CJ Sinal (805_CR164) 2000; 102 S Yoshimoto (805_CR114) 2013; 499 D Washo-Stultz (805_CR119) 2002; 177 AS Devlin (805_CR20) 2015; 11 S Sanyal (805_CR165) 2007; 104 N Jiao (805_CR94) 2018; 67 SA Joyce (805_CR99) 2014; 111 F Nevens (805_CR152) 2016; 375 RJ von Schwartzenberg (805_CR45) 2021; 595 M Watanabe (805_CR181) 2006; 439 N Kazemian (805_CR135) 2020; 10 J Meixiong (805_CR182) 2019; 116 JV Eldere (805_CR12) 1996; 62 LN Lucas (805_CR28) 2021 CJ Reissig (805_CR128) 2009; 99 BC Wertheim (805_CR38) 2009; 18 R Bibiloni (805_CR136) 2005; 100 TT Lu (805_CR163) 2000; 6 A Wilson (805_CR80) 2020; 10 TC McCarthy (805_CR172) 2005; 280 R Thakare (805_CR6) 2018; 38 Y Ma (805_CR108) 2013; 30 A Wahlström (805_CR7) 2017; 58 EA Franzosa (805_CR69) 2019; 4 DG Thanassi (805_CR52) 1997; 179 MH Foley (805_CR11) 2021; 118 C Cao (805_CR184) 2021; 600 J Li (805_CR8) 2019; 1865 SI Miller (805_CR51) 2016; 7 SM Huijghebaert (805_CR153) 1982; 44 J Sonoda (805_CR170) 2002; 99 Y He (805_CR88) 2018; 6 S Mudaliar (805_CR103) 2013; 145 RRM Maran (805_CR122) 2009; 328 JM Ridlon (805_CR126) 2016; 7 PC Pircher (805_CR166) 2003; 278 Y Kawamata (805_CR177) 2003; 278 CAM Stedman (805_CR167) 2005; 102 S Paramsothy (805_CR132) 2019; 156 J Lloyd-Price (805_CR74) 2019; 569 S Marion (805_CR18) 2020; 61 WA Walters (805_CR91) 2014; 588 KGMM Alberti (805_CR81) 2009; 120 E Molina-Molina (805_CR35) 2018; 48 M Meissner (805_CR37) 2011; 218 X Qian (805_CR68) 2020; 319 J Xiao (805_CR82) 2016; 6 JE Bisanz (805_CR92) 2019; 26 Y Ca (805_CR36) 1993; 265 DH Dapito (805_CR113) 2012; 21 CB Appleyard (805_CR139) 2011; 301 F Yang (805_CR123) 2007; 67 JM Ridlon (805_CR47) 2014; 30 T Inagaki (805_CR54) 2006; 103 C Bárcena (805_CR134) 2019; 25 T Streidl (805_CR17) 2021; 13 C Thomas (805_CR96) 2008; 7 L Ellegård (805_CR42) 2007; 61 X Song (805_CR149) 2020; 577 H Zhang (805_CR102) 2021; 22 SPS Saini (805_CR168) 2004; 65 H Tanaka (805_CR13) 2000; 66 K Wang (805_CR151) 2019; 26 BA White (805_CR15) 1980; 35 H Yu (805_CR183) 2019; 8 CM Theriot (805_CR59) 2016; 1 AA Adhikari (805_CR147) 2021; 16 T Kuno (805_CR33) 2018; 8 C Degirolamo (805_CR137) 2014; 7 AM Seekatz (805_CR130) 2018; 53 Y-D Wang (805_CR178) 2011; 54 A Wolfe (805_CR124) 2011; 338 BH Mullish (805_CR131) 2019; 68 J Miao (805_CR175) 2006; 281 D Gevers (805_CR71) 2014; 15 G Xie (805_CR112) 2016; 139 RM Gadaleta (805_CR125) 2011; 1812 J Yu (805_CR120) 2020; 11 KK Ryan (805_CR100) 2014; 509 SE McGarr (805_CR111) 2005; 39 L Ellegård (805_CR43) 2000; 54 JA Holt (805_CR161) 2003; 17 D Paik (805_CR148) 2022; 603 S Hang (805_CR146) 2019; 576 M Wang (805_CR27) 2020; 38 RM Gadaleta (805_CR78) 2011; 60 H Zhang (805_CR144) 2021; 7 JT Korpela (805_CR22) 1986; 25 MC Rea (805_CR57) 2010; 107 BA Neuschwander-Tetri (805_CR104) 2015; 385 S Laidlaw (805_CR127) 1990; 14 R Cabrera-Rubio (805_CR56) 2019; 9 A Vrieze (805_CR86) 2012; 143 E Gentry (805_CR26) 2021 K Oyama (805_CR142) 2002; 23 F Alemi (805_CR179) 2013; 144 A Honda (805_CR9) 2020; 61 M Makishima (805_CR158) 1999; 284 CD Fuchs (805_CR2) 2022 T Inagaki (805_CR160) 2005; 2 RA Quinn (805_CR24) 2020; 579 M Begley (805_CR50) 2005; 29 T Liu (805_CR53) 2017; 2 ML Jones (805_CR140) 2012; 66 A Vrieze (805_CR32) 2014; 60 H Duboc (805_CR72) 2013; 62 M Ðanić (805_CR101) 2018; 9 M Makishima (805_CR169) 2002; 296 A Heinken (805_CR75) 2019; 7 G Falony (805_CR90) 2016; 352 LCM Antunes (805_CR29) 2011; 55 C Thomas (805_CR180) 2009; 10 E Danese (805_CR39) 2017; 8 CM Theriot (805_CR31) 2014; 5 JW Cook (805_CR110) 1940; 145 W Jia (805_CR109) 2018; 15 DV Guzior (805_CR10) 2021; 9 L Serfaty (805_CR143) 2003; 38 J Tam (805_CR65) 2020; 117 M Vijay-Kumar (805_CR93) 2010; 328 CM Payne (805_CR118) 2008; 1 JA Sorg (805_CR61) 2008; 190 MM Thibaut (805_CR156) 2022; 28 DJ Parks (805_CR159) 1999; 284 JL Staudinger (805_CR171) 2001; 98 Y Tian (805_CR49) 2020; 11 YM Shah (805_CR79) 2007; 292 S Bhalla (805_CR174) 2004; 279 RE Ley (805_CR89) 2006; 444 D Qiao (805_CR117) 2001; 22 TH Sannasiddappa (805_CR48) 2017; 8 A Hughes (805_CR40) 2021; 19 SI Sayin (805_CR155) 2013; 17 AR Weingarden (805_CR66) 2014; 306 H Bernstein (805_CR115) 2005; 589 PA Dawson (805_CR23) 2015; 56 JR Swann (805_CR30) 2011; 108 RS Kootte (805_CR85) 2017; 26 P Pathak (805_CR97) 2018; 68 TJ Louie (805_CR67) 2011; 364 P Vavassori (805_CR76) 2009; 183 M Watanabe (805_CR98) 2004; 113 JM Ridlon (805_CR14) 2006; 47 C Manichanh (805_CR70) 2006; 55 F Dethloff (805_CR34) 2020; 11 S Katsuma (805_CR95) 2005; 329 J Van Eldere (805_CR21) 1988; 54 BV Jones (805_CR4) 2008; 105 S Lax (805_CR121) 2012; 130 A Wahlström (805_CR19) 2016; 24 JD Kang (805_CR64) 2019; 26 M Funabashi (805_CR16) 2020; 582 T Pearson (805_CR145) 2019; 8 M Watanabe (805_CR107) 2011; 286 E van Nood (805_CR129) 2013; 368 B Goodwin (805_CR162) 2000; 6 AF Hofmann (805_CR5) 2009; 14 F Bäckhed (805_CR84) 2004; 101 MA Hoffmann (805_CR25) 2022; 40 SI Grivennikov (805_CR116) 2010; 140 PJ Turnbaugh (805_CR83) 2006; 444 PJ Turnbaugh (805_CR1) 2007; 449 JP Hamilton (805_CR3) 2007; 293 N van Best (805_CR46) 2020; 11 S Huijghebaert (805_CR154) 1984; 20 L Zhao (805_CR133) 2020; 130 A Mencarelli (805_CR77) 2011; 668 Y Zhang (805_CR106) 2006; 103 DS Alberts (805_CR141) 2005; 97 P Louis (805_CR44) 2014; 12 A Parséus (805_CR105) 2017; 66 JI Robinson (805_CR60) 2019; 129 A Molinaro (805_CR157) 2018; 29 |
| References_xml | – volume: 102 start-page: 2063 year: 2005 end-page: 2068 ident: CR167 article-title: Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0409794102 – volume: 177 start-page: 129 year: 2002 end-page: 144 ident: CR119 article-title: Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis publication-title: Cancer Lett. doi: 10.1016/S0304-3835(01)00786-8 – volume: 439 start-page: 484 year: 2006 end-page: 489 ident: CR181 article-title: Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation publication-title: Nature doi: 10.1038/nature04330 – volume: 130 start-page: 2232 year: 2012 end-page: 2239 ident: CR121 article-title: Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis publication-title: Int. J. Cancer doi: 10.1002/ijc.26293 – volume: 375 start-page: 631 year: 2016 end-page: 643 ident: CR152 article-title: A placebo-controlled trial of obeticholic acid in primary biliary cholangitis publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa1509840 – volume: 218 start-page: 323 year: 2011 end-page: 329 ident: CR37 article-title: Voluntary wheel running increases bile acid as well as cholesterol excretion and decreases atherosclerosis in hypercholesterolemic mice publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2011.06.040 – volume: 265 start-page: 321 year: 1993 end-page: 327 ident: CR36 article-title: Chronic physical activity alters hepatobiliary excretory function in rats publication-title: J. Pharmacol. Exp. Ther. – volume: 7 start-page: 12 year: 2014 end-page: 18 ident: CR137 article-title: Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice publication-title: Cell Rep. doi: 10.1016/j.celrep.2014.02.032 – volume: 26 start-page: 611 year: 2017 end-page: 619.e6 ident: CR85 article-title: Improvement of insulin sensitivity after lean donor feces in metabolic syndrome is driven by baseline intestinal microbiota composition publication-title: Cell Metab. doi: 10.1016/j.cmet.2017.09.008 – volume: 30 start-page: 1447 year: 2013 end-page: 1457 ident: CR108 article-title: Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance publication-title: Pharm. Res. doi: 10.1007/s11095-013-0986-7 – volume: 55 start-page: 1494 year: 2011 end-page: 1503 ident: CR29 article-title: Effect of antibiotic treatment on the intestinal metabolome publication-title: Antimicrob. Agents Chemother. doi: 10.1128/AAC.01664-10 – volume: 23 start-page: 885 year: 2002 end-page: 892 ident: CR142 article-title: Reduction of hepatocarcinogenesis by ursodeoxycholic acid in rats publication-title: Carcinogenesis doi: 10.1093/carcin/23.5.885 – volume: 328 start-page: 228 year: 2010 end-page: 231 ident: CR93 article-title: Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5 publication-title: Science doi: 10.1126/science.1179721 – volume: 301 start-page: G1004 year: 2011 end-page: G1013 ident: CR139 article-title: Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00167.2011 – volume: 58 start-page: 412 year: 2017 end-page: 419 ident: CR7 article-title: Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota publication-title: J. Lipid Res. doi: 10.1194/jlr.M072819 – volume: 517 start-page: 205 year: 2015 end-page: 208 ident: CR63 article-title: Precision microbiome reconstitution restores bile acid mediated resistance to publication-title: Nature doi: 10.1038/nature13828 – volume: 8 start-page: 1581 year: 2017 ident: CR48 article-title: In vitro antibacterial activity of unconjugated and conjugated bile salts on publication-title: Front. Microbiol. doi: 10.3389/fmicb.2017.01581 – volume: 67 start-page: 1881 year: 2018 end-page: 1891 ident: CR94 article-title: Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD publication-title: Gut doi: 10.1136/gutjnl-2017-314307 – volume: 102 start-page: 731 year: 2000 end-page: 744 ident: CR164 article-title: Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis publication-title: Cell doi: 10.1016/S0092-8674(00)00062-3 – volume: 6 start-page: 507 year: 2000 end-page: 515 ident: CR163 article-title: Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors publication-title: Mol. Cell doi: 10.1016/S1097-2765(00)00050-2 – volume: 9 year: 2019 ident: CR56 article-title: Cholestasis induced by bile duct ligation promotes changes in the intestinal microbiome in mice publication-title: Sci. Rep. doi: 10.1038/s41598-019-48784-z – year: 2021 ident: CR28 article-title: Dominant bacterial phyla from the human gut show widespread ability to transform and conjugate bile acids publication-title: mSystems doi: 10.1128/mSystems.00805-21 – volume: 25 start-page: 1234 year: 2019 end-page: 1242 ident: CR134 article-title: Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice publication-title: Nat. Med. doi: 10.1038/s41591-019-0504-5 – volume: 6 year: 2011 ident: CR138 article-title: Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation publication-title: PLoS ONE doi: 10.1371/journal.pone.0022978 – volume: 502 start-page: 96 year: 2013 end-page: 99 ident: CR58 article-title: Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens publication-title: Nature doi: 10.1038/nature12503 – volume: 26 start-page: 27 year: 2019 end-page: 34.e4 ident: CR64 article-title: Bile acid 7α-dehydroxylating gut bacteria secrete antibiotics that inhibit : role of secondary bile acids publication-title: Cell Chem. Biol. doi: 10.1016/j.chembiol.2018.10.003 – volume: 44 start-page: 1030 year: 1982 end-page: 1034 ident: CR153 article-title: Specificity of bile salt sulfatase activity from sp. strains S1 publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.44.5.1030-1034.1982 – volume: 2 start-page: 217 year: 2005 end-page: 225 ident: CR160 article-title: Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis publication-title: Cell Metab. doi: 10.1016/j.cmet.2005.09.001 – volume: 14 start-page: 183 year: 1990 end-page: 188 ident: CR127 article-title: The taurine content of common foodstuffs publication-title: J. Parenter. Enter. Nutr. doi: 10.1177/0148607190014002183 – volume: 66 start-page: 1234 year: 2012 end-page: 1241 ident: CR140 article-title: Cholesterol lowering and inhibition of sterol absorption by NCIMB 30242: a randomized controlled trial publication-title: Eur. J. Clin. Nutr. doi: 10.1038/ejcn.2012.126 – volume: 11 year: 2020 ident: CR46 article-title: Bile acids drive the newborn’s gut microbiota maturation publication-title: Nat. Commun. doi: 10.1038/s41467-020-17183-8 – volume: 8 start-page: 52775 year: 2017 end-page: 52782 ident: CR39 article-title: Middle-distance running acutely influences the concentration and composition of serum bile acids: potential implications for cancer risk? publication-title: Oncotarget doi: 10.18632/oncotarget.17188 – volume: 284 start-page: 1362 year: 1999 end-page: 1365 ident: CR158 article-title: Identification of a nuclear receptor for bile acids publication-title: Science doi: 10.1126/science.284.5418.1362 – volume: 17 start-page: 1581 year: 2003 end-page: 1591 ident: CR161 article-title: Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis publication-title: Genes Dev. doi: 10.1101/gad.1083503 – volume: 65 start-page: 292 year: 2004 end-page: 300 ident: CR168 article-title: A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification publication-title: Mol. Pharmacol. doi: 10.1124/mol.65.2.292 – volume: 449 start-page: 804 year: 2007 end-page: 810 ident: CR1 article-title: The Human Microbiome Project publication-title: Nature doi: 10.1038/nature06244 – volume: 293 start-page: G256 year: 2007 end-page: G263 ident: CR3 article-title: Human cecal bile acids: concentration and spectrum publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00027.2007 – volume: 40 start-page: 411 year: 2022 end-page: 421 ident: CR25 article-title: High-confidence structural annotation of metabolites absent from spectral libraries publication-title: Nat. Biotechnol. doi: 10.1038/s41587-021-01045-9 – volume: 30 start-page: 332 year: 2014 end-page: 338 ident: CR47 article-title: Bile acids and the gut microbiome publication-title: Curr. Opin. Gastroenterol. doi: 10.1097/MOG.0000000000000057 – volume: 11 start-page: 685 year: 2015 end-page: 690 ident: CR20 article-title: A biosynthetic pathway for a prominent class of microbiota-derived bile acids publication-title: Nat. Chem. Biol. doi: 10.1038/nchembio.1864 – volume: 296 start-page: 1313 year: 2002 end-page: 1316 ident: CR169 article-title: Vitamin D receptor as an intestinal bile acid sensor publication-title: Science doi: 10.1126/science.1070477 – volume: 444 start-page: 1027 year: 2006 end-page: 1031 ident: CR83 article-title: An obesity-associated gut microbiome with increased capacity for energy harvest publication-title: Nature doi: 10.1038/nature05414 – volume: 21 start-page: 504 year: 2012 end-page: 516 ident: CR113 article-title: Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4 publication-title: Cancer Cell doi: 10.1016/j.ccr.2012.02.007 – volume: 19 start-page: 1723 year: 2021 end-page: 1725 ident: CR40 article-title: Exercise training reverses gut dysbiosis in patients with biopsy-proven nonalcoholic steatohepatitis: a proof of concept study publication-title: Clin. Gastroenterol. Hepatol. doi: 10.1016/j.cgh.2020.08.063 – volume: 285 start-page: 14486 year: 2010 end-page: 14494 ident: CR173 article-title: Regulation of bile acid synthesis by fat-soluble vitamins A and D publication-title: J. Biol. Chem. doi: 10.1074/jbc.M110.116004 – volume: 284 start-page: 1365 year: 1999 end-page: 1368 ident: CR159 article-title: Bile acids: natural ligands for an orphan nuclear receptor publication-title: Science doi: 10.1126/science.284.5418.1365 – volume: 66 start-page: 429 year: 2017 end-page: 437 ident: CR105 article-title: Microbiota-induced obesity requires farnesoid X receptor publication-title: Gut doi: 10.1136/gutjnl-2015-310283 – volume: 28 start-page: 223 year: 2022 end-page: 236 ident: CR156 article-title: Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation publication-title: Trends Mol. Med. doi: 10.1016/j.molmed.2021.12.006 – volume: 328 start-page: 469 year: 2009 end-page: 477 ident: CR122 article-title: Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.108.145409 – volume: 113 start-page: 1408 year: 2004 end-page: 1418 ident: CR98 article-title: Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c publication-title: J. Clin. Invest. doi: 10.1172/JCI21025 – volume: 7 start-page: 678 year: 2008 end-page: 693 ident: CR96 article-title: Targeting bile-acid signalling for metabolic diseases publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd2619 – volume: 11 start-page: 979 year: 2020 end-page: 996 ident: CR49 article-title: The microbiome modulating activity of bile acids publication-title: Gut Microbes doi: 10.1080/19490976.2020.1732268 – volume: 15 start-page: 382 year: 2014 end-page: 392 ident: CR71 article-title: The treatment-naïve microbiome in new-onset Crohn’s disease publication-title: Cell Host Microbe doi: 10.1016/j.chom.2014.02.005 – volume: 368 start-page: 407 year: 2013 end-page: 415 ident: CR129 article-title: Duodenal infusion of donor feces for recurrent publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa1205037 – volume: 588 start-page: 4223 year: 2014 end-page: 4233 ident: CR91 article-title: Meta-analyses of human gut microbes associated with obesity and IBD publication-title: FEBS Lett. doi: 10.1016/j.febslet.2014.09.039 – volume: 352 start-page: 560 year: 2016 end-page: 564 ident: CR90 article-title: Population-level analysis of gut microbiome variation publication-title: Science doi: 10.1126/science.aad3503 – volume: 298 start-page: 714 year: 2002 end-page: 719 ident: CR176 article-title: Identification of membrane-type receptor for bile acids (M-BAR) publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/S0006-291X(02)02550-0 – volume: 509 start-page: 183 year: 2014 end-page: 188 ident: CR100 article-title: FXR is a molecular target for the effects of vertical sleeve gastrectomy publication-title: Nature doi: 10.1038/nature13135 – volume: 45 start-page: 86 year: 2017 end-page: 100 ident: CR62 article-title: Inhibition of spore germination, growth, and toxin activity of clinically relevant strains by gut microbiota derived secondary bile acids publication-title: Anaerobe doi: 10.1016/j.anaerobe.2017.03.004 – volume: 7 year: 2019 ident: CR75 article-title: Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease publication-title: Microbiome doi: 10.1186/s40168-019-0689-3 – volume: 14 start-page: 2584 year: 2009 end-page: 2598 ident: CR5 article-title: The enterohepatic circulation of bile acids in mammals: form and functions publication-title: Front. Biosci. doi: 10.2741/3399 – volume: 280 start-page: 23232 year: 2005 end-page: 23242 ident: CR172 article-title: Vitamin D receptor-dependent regulation of colon multidrug resistance-associated protein 3 gene expression by bile acids publication-title: J. Biol. Chem. doi: 10.1074/jbc.M411520200 – volume: 62 start-page: 656 year: 1996 end-page: 661 ident: CR12 article-title: Tauroconjugation of cholic acid stimulates 7 alpha-dehydroxylation by fecal bacteria publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.62.2.656-661.1996 – volume: 62 start-page: 531 year: 2013 end-page: 539 ident: CR72 article-title: Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases publication-title: Gut doi: 10.1136/gutjnl-2012-302578 – volume: 7 start-page: 201 year: 2016 end-page: 215 ident: CR126 article-title: Taurocholic acid metabolism by gut microbes and colon cancer publication-title: Gut Microbes doi: 10.1080/19490976.2016.1150414 – volume: 4 start-page: 293 year: 2019 end-page: 305 ident: CR69 article-title: Gut microbiome structure and metabolic activity in inflammatory bowel disease publication-title: Nat. Microbiol. doi: 10.1038/s41564-018-0306-4 – volume: 10 start-page: 167 year: 2009 end-page: 177 ident: CR180 article-title: TGR5-mediated bile acid sensing controls glucose homeostasis publication-title: Cell Metab. doi: 10.1016/j.cmet.2009.08.001 – volume: 61 start-page: 1450 year: 2020 end-page: 1463 ident: CR18 article-title: Biogeography of microbial bile acid transformations along the murine gut publication-title: J. Lipid Res. doi: 10.1194/jlr.RA120001021 – year: 2021 ident: CR26 article-title: A synthesis-based reverse metabolomics approach for the discovery of chemical structures from humans and animals publication-title: Res. Sq. doi: 10.21203/rs.3.rs-820302/v1 – volume: 103 start-page: 3920 year: 2006 end-page: 3925 ident: CR54 article-title: Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0509592103 – volume: 579 start-page: 123 year: 2020 end-page: 129 ident: CR24 article-title: Global chemical impact of the microbiome includes novel bile acid conjugations publication-title: Nature doi: 10.1038/s41586-020-2047-9 – volume: 103 start-page: 1006 year: 2006 end-page: 1011 ident: CR106 article-title: Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0506982103 – volume: 1812 start-page: 851 year: 2011 end-page: 858 ident: CR125 article-title: Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine publication-title: Biochim. Biophys. Acta Mol. Basis Dis. doi: 10.1016/j.bbadis.2011.04.005 – volume: 116 start-page: 10525 year: 2019 end-page: 10530 ident: CR182 article-title: MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1903316116 – volume: 118 year: 2021 ident: CR11 article-title: bile salt hydrolase substrate specificity governs bacterial fitness and host colonization publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.2017709118 – volume: 1865 start-page: 895 year: 2019 end-page: 911 ident: CR8 article-title: Animal models to study bile acid metabolism publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbadis.2018.05.011 – volume: 25 start-page: 277 year: 1986 end-page: 284 ident: CR22 article-title: Multicomponent analysis of bile acids in faeces by anion exchange and capillary column gas-liquid chromatography: application in oxytetracycline treated subjects publication-title: J. Steroid Biochem. doi: 10.1016/0022-4731(86)90429-2 – volume: 56 start-page: 1085 year: 2015 end-page: 1099 ident: CR23 article-title: Intestinal transport and metabolism of bile acids publication-title: J. Lipid Res. doi: 10.1194/jlr.R054114 – volume: 1 start-page: 19 year: 2008 end-page: 47 ident: CR118 article-title: Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis publication-title: Clin. Exp. Gastroenterol. doi: 10.2147/CEG.S4343 – volume: 16 start-page: 1401 year: 2021 end-page: 1412 ident: CR147 article-title: A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases publication-title: ACS Chem. Biol. doi: 10.1021/acschembio.1c00192 – volume: 603 start-page: 907 year: 2022 end-page: 912 ident: CR148 article-title: Human gut bacteria produce Τ 17-modulating bile acid metabolites publication-title: Nature doi: 10.1038/s41586-022-04480-z – volume: 595 start-page: 272 year: 2021 end-page: 277 ident: CR45 article-title: Caloric restriction disrupts the microbiota and colonization resistance publication-title: Nature doi: 10.1038/s41586-021-03663-4 – volume: 589 start-page: 47 year: 2005 end-page: 65 ident: CR115 article-title: Bile acids as carcinogens in human gastrointestinal cancers publication-title: Mutat. Res. doi: 10.1016/j.mrrev.2004.08.001 – volume: 38 start-page: 203 year: 2003 end-page: 209 ident: CR143 article-title: Ursodeoxycholic acid therapy and the risk of colorectal adenoma in patients with primary biliary cirrhosis: an observational study publication-title: Hepatology doi: 10.1053/jhep.2003.50311 – volume: 11 start-page: 518 year: 2020 ident: CR34 article-title: Paroxetine administration affects microbiota and bile acid levels in mice publication-title: Front. Psychiatry doi: 10.3389/fpsyt.2020.00518 – volume: 6 year: 2016 ident: CR82 article-title: Prevalence of metabolic syndrome and its risk factors among rural adults in Nantong, China publication-title: Sci. Rep. doi: 10.1038/srep38089 – volume: 156 start-page: 1440 year: 2019 end-page: 1454.e2 ident: CR132 article-title: Specific bacteria and metabolites associated with response to fecal microbiota transplantation in patients with ulcerative colitis publication-title: Gastroenterology doi: 10.1053/j.gastro.2018.12.001 – volume: 582 start-page: 566 year: 2020 end-page: 570 ident: CR16 article-title: A metabolic pathway for bile acid dehydroxylation by the gut microbiome publication-title: Nature doi: 10.1038/s41586-020-2396-4 – volume: 61 start-page: 54 year: 2020 end-page: 69 ident: CR9 article-title: Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition publication-title: J. Lipid Res. doi: 10.1194/jlr.RA119000395 – volume: 7 start-page: e01541-16 year: 2016 ident: CR51 article-title: Antibiotic resistance and regulation of the Gram-negative bacterial outer membrane barrier by host innate immune molecules publication-title: mBio doi: 10.1128/mBio.01541-16 – volume: 183 start-page: 6251 year: 2009 end-page: 6261 ident: CR76 article-title: The bile acid receptor FXR is a modulator of intestinal innate immunity publication-title: J. Immunol. doi: 10.4049/jimmunol.0803978 – year: 2022 ident: CR2 article-title: Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology publication-title: Nat. Rev. Gastroenterol. Hepatol. doi: 10.1038/s41575-021-00566-7 – volume: 576 start-page: 143 year: 2019 end-page: 148 ident: CR146 article-title: Bile acid metabolites control TH17 and Treg cell differentiation publication-title: Nature doi: 10.1038/s41586-019-1785-z – volume: 278 start-page: 9435 year: 2003 end-page: 9440 ident: CR177 article-title: A G protein-coupled receptor responsive to bile acids publication-title: J. Biol. Chem. doi: 10.1074/jbc.M209706200 – volume: 385 start-page: 956 year: 2015 end-page: 965 ident: CR104 article-title: Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(14)61933-4 – volume: 281 start-page: 14537 year: 2006 end-page: 14546 ident: CR175 article-title: Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha publication-title: J. Biol. Chem. doi: 10.1074/jbc.M510713200 – volume: 143 start-page: 913 year: 2012 end-page: 916.e7 ident: CR86 article-title: Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome publication-title: Gastroenterology doi: 10.1053/j.gastro.2012.06.031 – volume: 98 start-page: 3369 year: 2001 end-page: 3374 ident: CR171 article-title: The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.051551698 – volume: 2 start-page: 17023 year: 2017 ident: CR53 article-title: NF-κB signaling in inflammation publication-title: Signal. Transduct. Target. Ther. doi: 10.1038/sigtrans.2017.23 – volume: 66 start-page: 2502 year: 2000 end-page: 2512 ident: CR13 article-title: Bile salt hydrolase of — biochemical and genetic characterization publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.66.6.2502-2512.2000 – volume: 99 start-page: 13801 year: 2002 end-page: 13806 ident: CR170 article-title: Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR) publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.212494599 – volume: 61 start-page: 938 year: 2007 end-page: 945 ident: CR42 article-title: Oat bran rapidly increases bile acid excretion and bile acid synthesis: an ileostomy study publication-title: Eur. J. Clin. Nutr. doi: 10.1038/sj.ejcn.1602607 – volume: 286 start-page: 26913 year: 2011 end-page: 26920 ident: CR107 article-title: Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.248203 – volume: 140 start-page: 883 year: 2010 end-page: 899 ident: CR116 article-title: Immunity, inflammation, and cancer publication-title: Cell doi: 10.1016/j.cell.2010.01.025 – volume: 117 start-page: 6792 year: 2020 end-page: 6800 ident: CR65 article-title: Intestinal bile acids directly modulate the structure and function of TcdB toxin publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1916965117 – volume: 26 start-page: 265 year: 2019 end-page: 272.e4 ident: CR92 article-title: Meta-analysis reveals reproducible gut microbiome alterations in response to a high-fat diet publication-title: Cell Host Microbe doi: 10.1016/j.chom.2019.06.013 – volume: 15 start-page: 111 year: 2018 end-page: 128 ident: CR109 article-title: Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis publication-title: Nat. Rev. Gastroenterol. Hepatol. doi: 10.1038/nrgastro.2017.119 – volume: 100 start-page: 1539 year: 2005 end-page: 1546 ident: CR136 article-title: VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis publication-title: Am. J. Gastroenterol. doi: 10.1111/j.1572-0241.2005.41794.x – volume: 668 start-page: 317 year: 2011 end-page: 324 ident: CR77 article-title: Inhibition of NF-κB by a PXR-dependent pathway mediates counter-regulatory activities of rifaximin on innate immunity in intestinal epithelial cells publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2011.06.058 – volume: 68 start-page: 1791 year: 2019 end-page: 1800 ident: CR131 article-title: Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent infection publication-title: Gut doi: 10.1136/gutjnl-2018-317842 – volume: 16 start-page: 885 year: 2017 end-page: 896 ident: CR55 article-title: Bile acids and intestinal microbiota in autoimmune cholestatic liver diseases publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2017.07.002 – volume: 292 start-page: G1114 year: 2007 end-page: G1122 ident: CR79 article-title: Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expression publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00528.2006 – volume: 54 start-page: 1421 year: 2011 end-page: 1432 ident: CR178 article-title: The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice publication-title: Hepatol. Baltim. Md. doi: 10.1002/hep.24525 – volume: 35 start-page: 103 year: 1980 end-page: 109 ident: CR15 article-title: Bile acid induction specificity of 7α-dehydroxylase activity in an intestinal species publication-title: Steroids doi: 10.1016/0039-128X(80)90115-4 – volume: 8 start-page: 617 year: 2019 end-page: 628 ident: CR145 article-title: Effects of ursodeoxycholic acid on the gut microbiome and colorectal adenoma development publication-title: Cancer Med. doi: 10.1002/cam4.1965 – volume: 60 start-page: 463 year: 2011 end-page: 472 ident: CR78 article-title: Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease publication-title: Gut doi: 10.1136/gut.2010.212159 – volume: 22 start-page: 991 year: 2021 ident: CR102 article-title: Obeticholic acid ameliorates obesity and hepatic steatosis by activating brown fat publication-title: Exp. Ther. Med. doi: 10.3892/etm.2021.10423 – volume: 53 start-page: 64 year: 2018 end-page: 73 ident: CR130 article-title: Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent infection publication-title: Anaerobe doi: 10.1016/j.anaerobe.2018.04.001 – volume: 8 year: 2018 ident: CR33 article-title: Reduction in hepatic secondary bile acids caused by short-term antibiotic-induced dysbiosis decreases mouse serum glucose and triglyceride levels publication-title: Sci. Rep. doi: 10.1038/s41598-018-19545-1 – volume: 104 start-page: 15665 year: 2007 end-page: 15670 ident: CR165 article-title: Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0706736104 – volume: 60 start-page: 824 year: 2014 end-page: 831 ident: CR32 article-title: Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity publication-title: J. Hepatol. doi: 10.1016/j.jhep.2013.11.034 – volume: 145 start-page: 574 year: 2013 end-page: 582.e1 ident: CR103 article-title: Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease publication-title: Gastroenterology doi: 10.1053/j.gastro.2013.05.042 – volume: 6 start-page: 517 year: 2000 end-page: 526 ident: CR162 article-title: A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis publication-title: Mol. Cell doi: 10.1016/S1097-2765(00)00051-4 – volume: 577 start-page: 410 year: 2020 end-page: 415 ident: CR149 article-title: Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis publication-title: Nature doi: 10.1038/s41586-019-1865-0 – volume: 17 start-page: 225 year: 2013 end-page: 235 ident: CR155 article-title: Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist publication-title: Cell Metab. doi: 10.1016/j.cmet.2013.01.003 – volume: 306 start-page: G310 year: 2014 end-page: G319 ident: CR66 article-title: Microbiota transplantation restores normal fecal bile acid composition in recurrent infection publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00282.2013 – volume: 29 start-page: 625 year: 2005 end-page: 651 ident: CR50 article-title: The interaction between bacteria and bile publication-title: FEMS Microbiol. Rev. doi: 10.1016/j.femsre.2004.09.003 – volume: 338 start-page: 12 year: 2011 end-page: 21 ident: CR124 article-title: Increased activation of the Wnt/β-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.111.179390 – volume: 29 start-page: 31 year: 2018 end-page: 41 ident: CR157 article-title: Role of bile acids in metabolic control publication-title: Trends Endocrinol. Metab. doi: 10.1016/j.tem.2017.11.002 – volume: 54 start-page: 306 year: 2000 end-page: 313 ident: CR43 article-title: Will recommended changes in fat and fibre intake affect cholesterol absorption and sterol excretion? An ileostomy study publication-title: Eur. J. Clin. Nutr. doi: 10.1038/sj.ejcn.1600940 – volume: 9 year: 2021 ident: CR10 article-title: Review: microbial transformations of human bile acids publication-title: Microbiome doi: 10.1186/s40168-021-01101-1 – volume: 10 year: 2020 ident: CR80 article-title: Attenuation of bile acid-mediated FXR and PXR activation in patients with Crohn’s disease publication-title: Sci. Rep. doi: 10.1038/s41598-020-58644-w – volume: 444 start-page: 1022 year: 2006 end-page: 1023 ident: CR89 article-title: Human gut microbes associated with obesity publication-title: Nature doi: 10.1038/4441022a – volume: 12 start-page: 661 year: 2014 end-page: 672 ident: CR44 article-title: The gut microbiota, bacterial metabolites and colorectal cancer publication-title: Nat. Rev. Microbiol. doi: 10.1038/nrmicro3344 – volume: 13 start-page: 1 year: 2021 end-page: 21 ident: CR17 article-title: The gut bacterium produces secondary bile acids and influences liver physiology in gnotobiotic mice publication-title: Gut Microbes doi: 10.1080/19490976.2020.1854008 – volume: 129 start-page: 3792 year: 2019 end-page: 3806 ident: CR60 article-title: Metabolomic networks connect host-microbiome processes to human infections publication-title: J. Clin. Invest. doi: 10.1172/JCI126905 – volume: 12 year: 2021 ident: CR150 article-title: Rationally designed bacterial consortia to treat chronic immune-mediated colitis and restore intestinal homeostasis publication-title: Nat. Commun. doi: 10.1038/s41467-021-23460-x – volume: 278 start-page: 27703 year: 2003 end-page: 27711 ident: CR166 article-title: Farnesoid X receptor regulates bile acid-amino acid conjugation publication-title: J. Biol. Chem. doi: 10.1074/jbc.M302128200 – volume: 9 start-page: 1382 year: 2018 ident: CR101 article-title: Pharmacological applications of bile acids and their derivatives in the treatment of metabolic syndrome publication-title: Front. Pharmacol. doi: 10.3389/fphar.2018.01382 – volume: 8 start-page: e48431 year: 2019 ident: CR183 article-title: MRGPRX4 is a bile acid receptor for human cholestatic itch publication-title: eLife doi: 10.7554/eLife.48431 – volume: 48 year: 2018 ident: CR35 article-title: Exercising the hepatobiliary-gut axis. The impact of physical activity performance publication-title: Eur. J. Clin. Invest. doi: 10.1111/eci.12958 – volume: 18 start-page: 1591 year: 2009 end-page: 1598 ident: CR38 article-title: Physical activity as a determinant of fecal bile acid levels publication-title: Cancer Epidemiol. Biomark. Prev. doi: 10.1158/1055-9965.EPI-08-1187 – volume: 139 start-page: 1764 year: 2016 end-page: 1775 ident: CR112 article-title: Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis publication-title: Int. J. Cancer doi: 10.1002/ijc.30219 – volume: 107 start-page: 9352 year: 2010 end-page: 9357 ident: CR57 article-title: Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0913554107 – volume: 68 start-page: 1574 year: 2018 end-page: 1588 ident: CR97 article-title: Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism publication-title: Hepatology doi: 10.1002/hep.29857 – volume: 22 start-page: 957 year: 2001 end-page: 964 ident: CR117 article-title: Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation publication-title: Carcinogenesis doi: 10.1093/carcin/22.6.957 – volume: 67 start-page: 863 year: 2007 end-page: 867 ident: CR123 article-title: Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-1078 – volume: 329 start-page: 386 year: 2005 end-page: 390 ident: CR95 article-title: Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1 publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2005.01.139 – volume: 38 start-page: 19 year: 2020 end-page: 26 ident: CR27 article-title: Mass spectrometry searches using MASST publication-title: Nat. Biotechnol. doi: 10.1038/s41587-019-0375-9 – volume: 319 start-page: G227 year: 2020 end-page: G237 ident: CR68 article-title: Ridinilazole, a narrow spectrum antibiotic for treatment of infection, enhances preservation of microbiota-dependent bile acids publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00046.2020 – volume: 54 start-page: 2112 year: 1988 end-page: 2117 ident: CR21 article-title: Isolation and identification of intestinal steroid-desulfating bacteria from rats and humans publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.54.8.2112-2117.1988 – volume: 20 start-page: 907 year: 1984 end-page: 912 ident: CR154 article-title: Specificity of bile salt sulfatase activity in man, mouse and rat intestinal microflora publication-title: J. Steroid Biochem. doi: 10.1016/0022-4731(84)90404-7 – volume: 144 start-page: 145 year: 2013 end-page: 154 ident: CR179 article-title: The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice publication-title: Gastroenterology doi: 10.1053/j.gastro.2012.09.055 – volume: 108 start-page: 4523 year: 2011 end-page: 4530 ident: CR30 article-title: Systemic gut microbial modulation of bile acid metabolism in host tissue compartments publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1006734107 – volume: 10 year: 2020 ident: CR135 article-title: The trans-kingdom battle between donor and recipient gut microbiome influences fecal microbiota transplantation outcome publication-title: Sci. Rep. doi: 10.1038/s41598-020-75162-x – volume: 55 start-page: 205 year: 2006 end-page: 211 ident: CR70 article-title: Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach publication-title: Gut doi: 10.1136/gut.2005.073817 – volume: 97 start-page: 846 year: 2005 end-page: 853 ident: CR141 article-title: Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence publication-title: J. Natl Cancer Inst. doi: 10.1093/jnci/dji144 – volume: 26 start-page: 222 year: 2019 end-page: 235.e5 ident: CR151 article-title: alleviates obesity and metabolic dysfunctions via production of succinate and secondary bile acids publication-title: Cell Rep. doi: 10.1016/j.celrep.2018.12.028 – volume: 105 start-page: 16731 year: 2008 end-page: 16736 ident: CR73 article-title: is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0804812105 – volume: 11 year: 2020 ident: CR120 article-title: Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis publication-title: Cell Death Dis. doi: 10.1038/s41419-020-02819-w – volume: 7 start-page: 207 year: 2021 ident: CR144 article-title: Ursodeoxycholic acid suppresses the malignant progression of colorectal cancer through TGR5-YAP axis publication-title: Cell Death Discov. doi: 10.1038/s41420-021-00589-8 – volume: 569 start-page: 655 year: 2019 end-page: 662 ident: CR74 article-title: Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases publication-title: Nature doi: 10.1038/s41586-019-1237-9 – volume: 111 start-page: 7421 year: 2014 end-page: 7426 ident: CR99 article-title: Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1323599111 – volume: 120 start-page: 1640 year: 2009 end-page: 1645 ident: CR81 article-title: Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.109.192644 – volume: 499 start-page: 97 year: 2013 end-page: 101 ident: CR114 article-title: Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome publication-title: Nature doi: 10.1038/nature12347 – volume: 6 year: 2018 ident: CR88 article-title: Linking gut microbiota, metabolic syndrome and economic status based on a population-level analysis publication-title: Microbiome doi: 10.1186/s40168-018-0557-6 – volume: 190 start-page: 2505 year: 2008 end-page: 2512 ident: CR61 article-title: Bile salts and glycine as cogerminants for spores publication-title: J. Bacteriol. doi: 10.1128/JB.01765-07 – volume: 145 start-page: 627 year: 1940 end-page: 627 ident: CR110 article-title: Production of tumours in mice by deoxycholic acid publication-title: Nature doi: 10.1038/145627a0 – volume: 364 start-page: 422 year: 2011 end-page: 431 ident: CR67 article-title: Fidaxomicin versus vancomycin for infection publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa0910812 – volume: 38 start-page: 1323 year: 2018 end-page: 1335 ident: CR6 article-title: Species differences in bile acids I. Plasma and urine bile acid composition publication-title: J. Appl. Toxicol. doi: 10.1002/jat.3644 – volume: 99 start-page: 1 year: 2009 end-page: 10 ident: CR128 article-title: Caffeinated energy drinks — a growing problem publication-title: Drug. Alcohol. Depend. doi: 10.1016/j.drugalcdep.2008.08.001 – volume: 39 start-page: 98 year: 2005 end-page: 109 ident: CR111 article-title: Diet, anaerobic bacterial metabolism, and colon cancer: a review of the literature publication-title: J. Clin. Gastroenterol. – volume: 1 start-page: e00045-15 year: 2016 ident: CR59 article-title: Antibiotic-induced alterations of the gut microbiota alter secondary bile acid production and allow for spore germination and outgrowth in the large intestine publication-title: mSphere doi: 10.1128/mSphere.00045-15 – volume: 24 start-page: 41 year: 2016 end-page: 50 ident: CR19 article-title: Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism publication-title: Cell Metab. doi: 10.1016/j.cmet.2016.05.005 – volume: 39 start-page: 395 year: 2020 end-page: 404 ident: CR41 article-title: Unconjugated and secondary bile acid profiles in response to higher-fat, lower-carbohydrate diet and associated with related gut microbiota: a 6-month randomized controlled-feeding trial publication-title: Clin. Nutr. doi: 10.1016/j.clnu.2019.02.037 – volume: 535 start-page: 376 year: 2016 end-page: 381 ident: CR87 article-title: Human gut microbes impact host serum metabolome and insulin sensitivity publication-title: Nature doi: 10.1038/nature18646 – volume: 179 start-page: 2512 year: 1997 end-page: 2518 ident: CR52 article-title: Active efflux of bile salts by publication-title: J. Bacteriol. doi: 10.1128/jb.179.8.2512-2518.1997 – volume: 5 year: 2014 ident: CR31 article-title: Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to infection publication-title: Nat. Commun. doi: 10.1038/ncomms4114 – volume: 101 start-page: 15718 year: 2004 end-page: 15723 ident: CR84 article-title: The gut microbiota as an environmental factor that regulates fat storage publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0407076101 – volume: 600 start-page: 170 year: 2021 end-page: 175 ident: CR184 article-title: Structure, function and pharmacology of human itch GPCRs publication-title: Nature doi: 10.1038/s41586-021-04126-6 – volume: 279 start-page: 45139 year: 2004 end-page: 45147 ident: CR174 article-title: Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1α: functional implications in hepatic cholesterol and glucose metabolism publication-title: J. Biol. Chem. doi: 10.1074/jbc.M405423200 – volume: 130 start-page: 438 year: 2020 end-page: 450 ident: CR133 article-title: A -rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome publication-title: J. Clin. Invest. doi: 10.1172/JCI130976 – volume: 47 start-page: 241 year: 2006 end-page: 259 ident: CR14 article-title: Bile salt biotransformations by human intestinal bacteria publication-title: J. Lipid Res. doi: 10.1194/jlr.R500013-JLR200 – volume: 105 start-page: 13580 year: 2008 end-page: 13585 ident: CR4 article-title: Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0804437105 – volume: 449 start-page: 804 year: 2007 ident: 805_CR1 publication-title: Nature doi: 10.1038/nature06244 – volume: 58 start-page: 412 year: 2017 ident: 805_CR7 publication-title: J. Lipid Res. doi: 10.1194/jlr.M072819 – volume: 569 start-page: 655 year: 2019 ident: 805_CR74 publication-title: Nature doi: 10.1038/s41586-019-1237-9 – volume: 589 start-page: 47 year: 2005 ident: 805_CR115 publication-title: Mutat. Res. doi: 10.1016/j.mrrev.2004.08.001 – volume: 38 start-page: 19 year: 2020 ident: 805_CR27 publication-title: Nat. Biotechnol. doi: 10.1038/s41587-019-0375-9 – volume: 22 start-page: 957 year: 2001 ident: 805_CR117 publication-title: Carcinogenesis doi: 10.1093/carcin/22.6.957 – volume: 444 start-page: 1027 year: 2006 ident: 805_CR83 publication-title: Nature doi: 10.1038/nature05414 – volume: 105 start-page: 13580 year: 2008 ident: 805_CR4 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0804437105 – volume: 7 start-page: 678 year: 2008 ident: 805_CR96 publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd2619 – volume: 579 start-page: 123 year: 2020 ident: 805_CR24 publication-title: Nature doi: 10.1038/s41586-020-2047-9 – volume: 2 start-page: 17023 year: 2017 ident: 805_CR53 publication-title: Signal. Transduct. Target. Ther. doi: 10.1038/sigtrans.2017.23 – volume: 18 start-page: 1591 year: 2009 ident: 805_CR38 publication-title: Cancer Epidemiol. Biomark. Prev. doi: 10.1158/1055-9965.EPI-08-1187 – volume: 55 start-page: 205 year: 2006 ident: 805_CR70 publication-title: Gut doi: 10.1136/gut.2005.073817 – volume: 61 start-page: 54 year: 2020 ident: 805_CR9 publication-title: J. Lipid Res. doi: 10.1194/jlr.RA119000395 – volume: 60 start-page: 824 year: 2014 ident: 805_CR32 publication-title: J. Hepatol. doi: 10.1016/j.jhep.2013.11.034 – volume: 29 start-page: 625 year: 2005 ident: 805_CR50 publication-title: FEMS Microbiol. Rev. doi: 10.1016/j.femsre.2004.09.003 – volume: 7 start-page: e01541-16 year: 2016 ident: 805_CR51 publication-title: mBio doi: 10.1128/mBio.01541-16 – volume: 60 start-page: 463 year: 2011 ident: 805_CR78 publication-title: Gut doi: 10.1136/gut.2010.212159 – volume: 9 year: 2021 ident: 805_CR10 publication-title: Microbiome doi: 10.1186/s40168-021-01101-1 – volume: 107 start-page: 9352 year: 2010 ident: 805_CR57 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0913554107 – volume: 10 year: 2020 ident: 805_CR80 publication-title: Sci. Rep. doi: 10.1038/s41598-020-58644-w – volume: 298 start-page: 714 year: 2002 ident: 805_CR176 publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/S0006-291X(02)02550-0 – volume: 385 start-page: 956 year: 2015 ident: 805_CR104 publication-title: Lancet doi: 10.1016/S0140-6736(14)61933-4 – volume: 54 start-page: 306 year: 2000 ident: 805_CR43 publication-title: Eur. J. Clin. Nutr. doi: 10.1038/sj.ejcn.1600940 – volume: 54 start-page: 1421 year: 2011 ident: 805_CR178 publication-title: Hepatol. Baltim. Md. doi: 10.1002/hep.24525 – volume: 53 start-page: 64 year: 2018 ident: 805_CR130 publication-title: Anaerobe doi: 10.1016/j.anaerobe.2018.04.001 – volume: 1812 start-page: 851 year: 2011 ident: 805_CR125 publication-title: Biochim. Biophys. Acta Mol. Basis Dis. doi: 10.1016/j.bbadis.2011.04.005 – volume: 668 start-page: 317 year: 2011 ident: 805_CR77 publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2011.06.058 – volume: 319 start-page: G227 year: 2020 ident: 805_CR68 publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00046.2020 – volume: 40 start-page: 411 year: 2022 ident: 805_CR25 publication-title: Nat. Biotechnol. doi: 10.1038/s41587-021-01045-9 – volume: 576 start-page: 143 year: 2019 ident: 805_CR146 publication-title: Nature doi: 10.1038/s41586-019-1785-z – volume: 12 year: 2021 ident: 805_CR150 publication-title: Nat. Commun. doi: 10.1038/s41467-021-23460-x – volume: 145 start-page: 627 year: 1940 ident: 805_CR110 publication-title: Nature doi: 10.1038/145627a0 – volume: 278 start-page: 9435 year: 2003 ident: 805_CR177 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M209706200 – volume: 25 start-page: 277 year: 1986 ident: 805_CR22 publication-title: J. Steroid Biochem. doi: 10.1016/0022-4731(86)90429-2 – volume: 15 start-page: 111 year: 2018 ident: 805_CR109 publication-title: Nat. Rev. Gastroenterol. Hepatol. doi: 10.1038/nrgastro.2017.119 – volume: 66 start-page: 1234 year: 2012 ident: 805_CR140 publication-title: Eur. J. Clin. Nutr. doi: 10.1038/ejcn.2012.126 – volume: 23 start-page: 885 year: 2002 ident: 805_CR142 publication-title: Carcinogenesis doi: 10.1093/carcin/23.5.885 – volume: 328 start-page: 469 year: 2009 ident: 805_CR122 publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.108.145409 – volume: 104 start-page: 15665 year: 2007 ident: 805_CR165 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0706736104 – volume: 26 start-page: 265 year: 2019 ident: 805_CR92 publication-title: Cell Host Microbe doi: 10.1016/j.chom.2019.06.013 – volume: 139 start-page: 1764 year: 2016 ident: 805_CR112 publication-title: Int. J. Cancer doi: 10.1002/ijc.30219 – volume: 29 start-page: 31 year: 2018 ident: 805_CR157 publication-title: Trends Endocrinol. Metab. doi: 10.1016/j.tem.2017.11.002 – volume: 45 start-page: 86 year: 2017 ident: 805_CR62 publication-title: Anaerobe doi: 10.1016/j.anaerobe.2017.03.004 – volume: 30 start-page: 332 year: 2014 ident: 805_CR47 publication-title: Curr. Opin. Gastroenterol. doi: 10.1097/MOG.0000000000000057 – volume: 306 start-page: G310 year: 2014 ident: 805_CR66 publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00282.2013 – volume: 66 start-page: 429 year: 2017 ident: 805_CR105 publication-title: Gut doi: 10.1136/gutjnl-2015-310283 – volume: 218 start-page: 323 year: 2011 ident: 805_CR37 publication-title: Atherosclerosis doi: 10.1016/j.atherosclerosis.2011.06.040 – volume: 116 start-page: 10525 year: 2019 ident: 805_CR182 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1903316116 – volume: 62 start-page: 531 year: 2013 ident: 805_CR72 publication-title: Gut doi: 10.1136/gutjnl-2012-302578 – volume: 293 start-page: G256 year: 2007 ident: 805_CR3 publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00027.2007 – volume: 4 start-page: 293 year: 2019 ident: 805_CR69 publication-title: Nat. Microbiol. doi: 10.1038/s41564-018-0306-4 – volume: 535 start-page: 376 year: 2016 ident: 805_CR87 publication-title: Nature doi: 10.1038/nature18646 – volume: 117 start-page: 6792 year: 2020 ident: 805_CR65 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1916965117 – volume: 98 start-page: 3369 year: 2001 ident: 805_CR171 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.051551698 – volume: 62 start-page: 656 year: 1996 ident: 805_CR12 publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.62.2.656-661.1996 – volume: 129 start-page: 3792 year: 2019 ident: 805_CR60 publication-title: J. Clin. Invest. doi: 10.1172/JCI126905 – volume: 111 start-page: 7421 year: 2014 ident: 805_CR99 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1323599111 – volume: 21 start-page: 504 year: 2012 ident: 805_CR113 publication-title: Cancer Cell doi: 10.1016/j.ccr.2012.02.007 – volume: 30 start-page: 1447 year: 2013 ident: 805_CR108 publication-title: Pharm. Res. doi: 10.1007/s11095-013-0986-7 – volume: 102 start-page: 731 year: 2000 ident: 805_CR164 publication-title: Cell doi: 10.1016/S0092-8674(00)00062-3 – volume: 265 start-page: 321 year: 1993 ident: 805_CR36 publication-title: J. Pharmacol. Exp. Ther. – volume: 284 start-page: 1362 year: 1999 ident: 805_CR158 publication-title: Science doi: 10.1126/science.284.5418.1362 – volume: 26 start-page: 222 year: 2019 ident: 805_CR151 publication-title: Cell Rep. doi: 10.1016/j.celrep.2018.12.028 – volume: 9 year: 2019 ident: 805_CR56 publication-title: Sci. Rep. doi: 10.1038/s41598-019-48784-z – volume: 284 start-page: 1365 year: 1999 ident: 805_CR159 publication-title: Science doi: 10.1126/science.284.5418.1365 – volume: 16 start-page: 885 year: 2017 ident: 805_CR55 publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2017.07.002 – volume: 120 start-page: 1640 year: 2009 ident: 805_CR81 publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.109.192644 – volume: 39 start-page: 98 year: 2005 ident: 805_CR111 publication-title: J. Clin. Gastroenterol. – volume: 439 start-page: 484 year: 2006 ident: 805_CR181 publication-title: Nature doi: 10.1038/nature04330 – volume: 285 start-page: 14486 year: 2010 ident: 805_CR173 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M110.116004 – volume: 6 start-page: 507 year: 2000 ident: 805_CR163 publication-title: Mol. Cell doi: 10.1016/S1097-2765(00)00050-2 – volume: 7 year: 2019 ident: 805_CR75 publication-title: Microbiome doi: 10.1186/s40168-019-0689-3 – volume: 11 start-page: 685 year: 2015 ident: 805_CR20 publication-title: Nat. Chem. Biol. doi: 10.1038/nchembio.1864 – volume: 292 start-page: G1114 year: 2007 ident: 805_CR79 publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00528.2006 – volume: 499 start-page: 97 year: 2013 ident: 805_CR114 publication-title: Nature doi: 10.1038/nature12347 – volume: 338 start-page: 12 year: 2011 ident: 805_CR124 publication-title: J. Pharmacol. Exp. Ther. doi: 10.1124/jpet.111.179390 – volume: 143 start-page: 913 year: 2012 ident: 805_CR86 publication-title: Gastroenterology doi: 10.1053/j.gastro.2012.06.031 – volume: 105 start-page: 16731 year: 2008 ident: 805_CR73 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0804812105 – volume: 61 start-page: 938 year: 2007 ident: 805_CR42 publication-title: Eur. J. Clin. Nutr. doi: 10.1038/sj.ejcn.1602607 – volume: 100 start-page: 1539 year: 2005 ident: 805_CR136 publication-title: Am. J. Gastroenterol. doi: 10.1111/j.1572-0241.2005.41794.x – volume: 55 start-page: 1494 year: 2011 ident: 805_CR29 publication-title: Antimicrob. Agents Chemother. doi: 10.1128/AAC.01664-10 – volume: 12 start-page: 661 year: 2014 ident: 805_CR44 publication-title: Nat. Rev. Microbiol. doi: 10.1038/nrmicro3344 – volume: 103 start-page: 3920 year: 2006 ident: 805_CR54 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0509592103 – volume: 280 start-page: 23232 year: 2005 ident: 805_CR172 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M411520200 – volume: 26 start-page: 27 year: 2019 ident: 805_CR64 publication-title: Cell Chem. Biol. doi: 10.1016/j.chembiol.2018.10.003 – volume: 130 start-page: 438 year: 2020 ident: 805_CR133 publication-title: J. Clin. Invest. doi: 10.1172/JCI130976 – volume: 140 start-page: 883 year: 2010 ident: 805_CR116 publication-title: Cell doi: 10.1016/j.cell.2010.01.025 – volume: 14 start-page: 183 year: 1990 ident: 805_CR127 publication-title: J. Parenter. Enter. Nutr. doi: 10.1177/0148607190014002183 – volume: 179 start-page: 2512 year: 1997 ident: 805_CR52 publication-title: J. Bacteriol. doi: 10.1128/jb.179.8.2512-2518.1997 – volume: 16 start-page: 1401 year: 2021 ident: 805_CR147 publication-title: ACS Chem. Biol. doi: 10.1021/acschembio.1c00192 – volume: 328 start-page: 228 year: 2010 ident: 805_CR93 publication-title: Science doi: 10.1126/science.1179721 – volume: 26 start-page: 611 year: 2017 ident: 805_CR85 publication-title: Cell Metab. doi: 10.1016/j.cmet.2017.09.008 – volume: 7 start-page: 201 year: 2016 ident: 805_CR126 publication-title: Gut Microbes doi: 10.1080/19490976.2016.1150414 – volume: 577 start-page: 410 year: 2020 ident: 805_CR149 publication-title: Nature doi: 10.1038/s41586-019-1865-0 – volume: 25 start-page: 1234 year: 2019 ident: 805_CR134 publication-title: Nat. Med. doi: 10.1038/s41591-019-0504-5 – volume: 190 start-page: 2505 year: 2008 ident: 805_CR61 publication-title: J. Bacteriol. doi: 10.1128/JB.01765-07 – volume: 13 start-page: 1 year: 2021 ident: 805_CR17 publication-title: Gut Microbes doi: 10.1080/19490976.2020.1854008 – volume: 600 start-page: 170 year: 2021 ident: 805_CR184 publication-title: Nature doi: 10.1038/s41586-021-04126-6 – volume: 61 start-page: 1450 year: 2020 ident: 805_CR18 publication-title: J. Lipid Res. doi: 10.1194/jlr.RA120001021 – volume: 28 start-page: 223 year: 2022 ident: 805_CR156 publication-title: Trends Mol. Med. doi: 10.1016/j.molmed.2021.12.006 – volume: 588 start-page: 4223 year: 2014 ident: 805_CR91 publication-title: FEBS Lett. doi: 10.1016/j.febslet.2014.09.039 – volume: 11 start-page: 518 year: 2020 ident: 805_CR34 publication-title: Front. Psychiatry doi: 10.3389/fpsyt.2020.00518 – volume: 1865 start-page: 895 year: 2019 ident: 805_CR8 publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbadis.2018.05.011 – volume: 183 start-page: 6251 year: 2009 ident: 805_CR76 publication-title: J. Immunol. doi: 10.4049/jimmunol.0803978 – volume: 329 start-page: 386 year: 2005 ident: 805_CR95 publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2005.01.139 – volume: 5 year: 2014 ident: 805_CR31 publication-title: Nat. Commun. doi: 10.1038/ncomms4114 – volume: 68 start-page: 1791 year: 2019 ident: 805_CR131 publication-title: Gut doi: 10.1136/gutjnl-2018-317842 – volume: 66 start-page: 2502 year: 2000 ident: 805_CR13 publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.66.6.2502-2512.2000 – volume: 68 start-page: 1574 year: 2018 ident: 805_CR97 publication-title: Hepatology doi: 10.1002/hep.29857 – volume: 99 start-page: 13801 year: 2002 ident: 805_CR170 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.212494599 – volume: 364 start-page: 422 year: 2011 ident: 805_CR67 publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa0910812 – volume: 103 start-page: 1006 year: 2006 ident: 805_CR106 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0506982103 – volume: 2 start-page: 217 year: 2005 ident: 805_CR160 publication-title: Cell Metab. doi: 10.1016/j.cmet.2005.09.001 – volume: 368 start-page: 407 year: 2013 ident: 805_CR129 publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa1205037 – volume: 144 start-page: 145 year: 2013 ident: 805_CR179 publication-title: Gastroenterology doi: 10.1053/j.gastro.2012.09.055 – volume: 7 start-page: 12 year: 2014 ident: 805_CR137 publication-title: Cell Rep. doi: 10.1016/j.celrep.2014.02.032 – volume: 102 start-page: 2063 year: 2005 ident: 805_CR167 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0409794102 – year: 2021 ident: 805_CR28 publication-title: mSystems doi: 10.1128/mSystems.00805-21 – volume: 44 start-page: 1030 year: 1982 ident: 805_CR153 publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.44.5.1030-1034.1982 – volume: 11 start-page: 979 year: 2020 ident: 805_CR49 publication-title: Gut Microbes doi: 10.1080/19490976.2020.1732268 – volume: 17 start-page: 1581 year: 2003 ident: 805_CR161 publication-title: Genes Dev. doi: 10.1101/gad.1083503 – volume: 603 start-page: 907 year: 2022 ident: 805_CR148 publication-title: Nature doi: 10.1038/s41586-022-04480-z – volume: 156 start-page: 1440 year: 2019 ident: 805_CR132 publication-title: Gastroenterology doi: 10.1053/j.gastro.2018.12.001 – volume: 20 start-page: 907 year: 1984 ident: 805_CR154 publication-title: J. Steroid Biochem. doi: 10.1016/0022-4731(84)90404-7 – volume: 10 year: 2020 ident: 805_CR135 publication-title: Sci. Rep. doi: 10.1038/s41598-020-75162-x – volume: 130 start-page: 2232 year: 2012 ident: 805_CR121 publication-title: Int. J. Cancer doi: 10.1002/ijc.26293 – volume: 10 start-page: 167 year: 2009 ident: 805_CR180 publication-title: Cell Metab. doi: 10.1016/j.cmet.2009.08.001 – volume: 352 start-page: 560 year: 2016 ident: 805_CR90 publication-title: Science doi: 10.1126/science.aad3503 – volume: 509 start-page: 183 year: 2014 ident: 805_CR100 publication-title: Nature doi: 10.1038/nature13135 – year: 2021 ident: 805_CR26 publication-title: Res. Sq. doi: 10.21203/rs.3.rs-820302/v1 – volume: 279 start-page: 45139 year: 2004 ident: 805_CR174 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M405423200 – volume: 444 start-page: 1022 year: 2006 ident: 805_CR89 publication-title: Nature doi: 10.1038/4441022a – volume: 67 start-page: 863 year: 2007 ident: 805_CR123 publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-1078 – volume: 296 start-page: 1313 year: 2002 ident: 805_CR169 publication-title: Science doi: 10.1126/science.1070477 – volume: 582 start-page: 566 year: 2020 ident: 805_CR16 publication-title: Nature doi: 10.1038/s41586-020-2396-4 – volume: 108 start-page: 4523 year: 2011 ident: 805_CR30 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1006734107 – volume: 19 start-page: 1723 year: 2021 ident: 805_CR40 publication-title: Clin. Gastroenterol. Hepatol. doi: 10.1016/j.cgh.2020.08.063 – volume: 47 start-page: 241 year: 2006 ident: 805_CR14 publication-title: J. Lipid Res. doi: 10.1194/jlr.R500013-JLR200 – volume: 113 start-page: 1408 year: 2004 ident: 805_CR98 publication-title: J. Clin. Invest. doi: 10.1172/JCI21025 – volume: 286 start-page: 26913 year: 2011 ident: 805_CR107 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M111.248203 – volume: 38 start-page: 1323 year: 2018 ident: 805_CR6 publication-title: J. Appl. Toxicol. doi: 10.1002/jat.3644 – volume: 502 start-page: 96 year: 2013 ident: 805_CR58 publication-title: Nature doi: 10.1038/nature12503 – volume: 97 start-page: 846 year: 2005 ident: 805_CR141 publication-title: J. Natl Cancer Inst. doi: 10.1093/jnci/dji144 – volume: 22 start-page: 991 year: 2021 ident: 805_CR102 publication-title: Exp. Ther. Med. doi: 10.3892/etm.2021.10423 – volume: 15 start-page: 382 year: 2014 ident: 805_CR71 publication-title: Cell Host Microbe doi: 10.1016/j.chom.2014.02.005 – volume: 118 year: 2021 ident: 805_CR11 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.2017709118 – volume: 54 start-page: 2112 year: 1988 ident: 805_CR21 publication-title: Appl. Environ. Microbiol. doi: 10.1128/aem.54.8.2112-2117.1988 – volume: 177 start-page: 129 year: 2002 ident: 805_CR119 publication-title: Cancer Lett. doi: 10.1016/S0304-3835(01)00786-8 – volume: 375 start-page: 631 year: 2016 ident: 805_CR152 publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa1509840 – volume: 8 start-page: 1581 year: 2017 ident: 805_CR48 publication-title: Front. Microbiol. doi: 10.3389/fmicb.2017.01581 – volume: 6 year: 2016 ident: 805_CR82 publication-title: Sci. Rep. doi: 10.1038/srep38089 – volume: 8 start-page: 52775 year: 2017 ident: 805_CR39 publication-title: Oncotarget doi: 10.18632/oncotarget.17188 – volume: 56 start-page: 1085 year: 2015 ident: 805_CR23 publication-title: J. Lipid Res. doi: 10.1194/jlr.R054114 – volume: 6 year: 2018 ident: 805_CR88 publication-title: Microbiome doi: 10.1186/s40168-018-0557-6 – volume: 8 start-page: e48431 year: 2019 ident: 805_CR183 publication-title: eLife doi: 10.7554/eLife.48431 – volume: 281 start-page: 14537 year: 2006 ident: 805_CR175 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M510713200 – volume: 48 year: 2018 ident: 805_CR35 publication-title: Eur. J. Clin. Invest. doi: 10.1111/eci.12958 – volume: 517 start-page: 205 year: 2015 ident: 805_CR63 publication-title: Nature doi: 10.1038/nature13828 – volume: 101 start-page: 15718 year: 2004 ident: 805_CR84 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0407076101 – volume: 8 year: 2018 ident: 805_CR33 publication-title: Sci. Rep. doi: 10.1038/s41598-018-19545-1 – volume: 9 start-page: 1382 year: 2018 ident: 805_CR101 publication-title: Front. Pharmacol. doi: 10.3389/fphar.2018.01382 – volume: 1 start-page: 19 year: 2008 ident: 805_CR118 publication-title: Clin. Exp. Gastroenterol. doi: 10.2147/CEG.S4343 – volume: 6 year: 2011 ident: 805_CR138 publication-title: PLoS ONE doi: 10.1371/journal.pone.0022978 – volume: 278 start-page: 27703 year: 2003 ident: 805_CR166 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M302128200 – year: 2022 ident: 805_CR2 publication-title: Nat. Rev. Gastroenterol. Hepatol. doi: 10.1038/s41575-021-00566-7 – volume: 14 start-page: 2584 year: 2009 ident: 805_CR5 publication-title: Front. Biosci. doi: 10.2741/3399 – volume: 99 start-page: 1 year: 2009 ident: 805_CR128 publication-title: Drug. Alcohol. Depend. doi: 10.1016/j.drugalcdep.2008.08.001 – volume: 24 start-page: 41 year: 2016 ident: 805_CR19 publication-title: Cell Metab. doi: 10.1016/j.cmet.2016.05.005 – volume: 11 year: 2020 ident: 805_CR46 publication-title: Nat. Commun. doi: 10.1038/s41467-020-17183-8 – volume: 67 start-page: 1881 year: 2018 ident: 805_CR94 publication-title: Gut doi: 10.1136/gutjnl-2017-314307 – volume: 17 start-page: 225 year: 2013 ident: 805_CR155 publication-title: Cell Metab. doi: 10.1016/j.cmet.2013.01.003 – volume: 65 start-page: 292 year: 2004 ident: 805_CR168 publication-title: Mol. Pharmacol. doi: 10.1124/mol.65.2.292 – volume: 595 start-page: 272 year: 2021 ident: 805_CR45 publication-title: Nature doi: 10.1038/s41586-021-03663-4 – volume: 6 start-page: 517 year: 2000 ident: 805_CR162 publication-title: Mol. Cell doi: 10.1016/S1097-2765(00)00051-4 – volume: 8 start-page: 617 year: 2019 ident: 805_CR145 publication-title: Cancer Med. doi: 10.1002/cam4.1965 – volume: 35 start-page: 103 year: 1980 ident: 805_CR15 publication-title: Steroids doi: 10.1016/0039-128X(80)90115-4 – volume: 39 start-page: 395 year: 2020 ident: 805_CR41 publication-title: Clin. Nutr. doi: 10.1016/j.clnu.2019.02.037 – volume: 11 year: 2020 ident: 805_CR120 publication-title: Cell Death Dis. doi: 10.1038/s41419-020-02819-w – volume: 301 start-page: G1004 year: 2011 ident: 805_CR139 publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00167.2011 – volume: 145 start-page: 574 year: 2013 ident: 805_CR103 publication-title: Gastroenterology doi: 10.1053/j.gastro.2013.05.042 – volume: 38 start-page: 203 year: 2003 ident: 805_CR143 publication-title: Hepatology doi: 10.1053/jhep.2003.50311 – volume: 1 start-page: e00045-15 year: 2016 ident: 805_CR59 publication-title: mSphere doi: 10.1128/mSphere.00045-15 – volume: 7 start-page: 207 year: 2021 ident: 805_CR144 publication-title: Cell Death Discov. doi: 10.1038/s41420-021-00589-8 |
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| Title | Bile acids and the gut microbiota: metabolic interactions and impacts on disease |
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