Review of Metabolomics-Based Biomarker Research for Parkinson’s Disease

• Published in: Molecular neurobiology Vol. 59; no. 2; pp. 1041 - 1057
• Main Authors: Li, Xin, Fan, Xiaoying, Yang, Hongtian, Liu, Yufeng
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2022; Springer Nature B.V
• Subjects: Aged; Biomarkers; Biomarkers - metabolism; Biomedical and Life Sciences; Biomedicine; Cell Biology; Diagnosis; Humans; Metabolism; Metabolites; Metabolomics; Metabolomics - methods; Movement disorders; Neurobiology; Neurodegenerative Diseases; Neurology; Neurosciences; Parkinson Disease - diagnosis; Parkinson Disease - metabolism; Parkinson's disease; Quality of life; Sensitivity and Specificity; Biomarker discovery; Metabolomics; Early diagnosis; Parkinson’s disease; Biomarker validation; Therapeutic targets

Parkinson’s disease (PD), as the second most common neurodegenerative disease, is seriously affecting the life quality of the elderly. However, there is still a lack of efficient medical methods to diagnosis PD before apparent symptoms occur. In recent years, clinical biomarkers including genetic, i...