PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone - Laurino, Lisandro; Wang, Xiaoxin X; de la Houssaye, Becky A; Sosa, Lucas; Dupraz, Sebastian; Cáceres, Alfredo; Pfenninger, Karl H; Quiroga, Santiago (Journal of cell science, 2005)
Keywords: Animals; Cell Differentiation - drug effects; Cell Differentiation - physiology; Cell Membrane - drug effects; Cell Membrane - metabolism; Cells, Cultured; Central Nervous System - cytology; Central Nervous System - embryology; Central Nervous System - growth & development; Enzyme Activation - drug effects; Enzyme Activation - physiology; Enzyme Inhibitors; Exocytosis - drug effects; Exocytosis - physiology; Growth Cones - drug effects; Growth Cones - metabolism; Growth Cones - ultrastructure; Hippocampus - cytology; Hippocampus - embryology; Hippocampus - growth & development; Insulin-Like Growth Factor I - metabolism; Insulin-Like Growth Factor I - pharmacology; Membrane Fusion - drug effects; Membrane Fusion - physiology; Microtubules - drug effects; Microtubules - metabolism; Phosphatidylinositol 3-Kinases - antagonists & inhibitors; Phosphatidylinositol 3-Kinases - metabolism; Protein Transport - drug effects; Protein Transport - physiology; Rats; Signal Transduction - physiology; Transport Vesicles - drug effects; Transport Vesicles - metabolism; Transport Vesicles - ultrastructure