Survival Benefit of and Indications for Adjuvant Chemotherapy for Resected Colorectal Liver Metastases—a Japanese Nationwide Survey

• Published in: Journal of gastrointestinal surgery Vol. 24; no. 6; pp. 1244 - 1260
• Main Authors: Kobayashi, Shin, Beppu, Toru, Honda, Goro, Yamamoto, Masakazu, Takahashi, Keiichi, Endo, Itaru, Hasegawa, Kiyoshi, Kotake, Kenjiro, Itabashi, Michio, Hashiguchi, Yojiro, Kotera, Yoshihito, Sakamoto, Katsunori, Yamaguchi, Tatsuro, Morita, Satoshi, Tabuchi, Ken, Miyazaki, Masaru, Sugihara, Kenichi
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2020; Springer Nature B.V
• Subjects: Chemotherapy; Chemotherapy, Adjuvant; Colorectal cancer; Colorectal Neoplasms - surgery; Gastroenterology; Gastrointestinal surgery; Hepatectomy; Hospitals; Humans; Infectious diseases; Japan - epidemiology; Liver; Liver Neoplasms - drug therapy; Liver Neoplasms - surgery; Medicine; Medicine & Public Health; Metastasis; Original Article; Patients; Prognosis; Retrospective Studies; Surgery; Japan; Adjuvant chemotherapy; Colorectal liver metastasis; Real-world data

Background The survival benefit of and indications for adjuvant chemotherapy (AC) for colorectal liver metastases (CRLM) remain unclear. Methods Patients who were diagnosed with liver-limited CRLM between 2005 and 2007 and subsequently underwent R0 resection without preoperative chemotherapy were id...