Immunogenicity of a Fourth Homologous Dose of NVX-CoV2373

Boosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody specific for the ancestral strain and omicron variants. Whether the elicited antibodies protect against infection is unclear.

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Published inThe New England journal of medicine Vol. 388; no. 9; pp. 857 - 859
Main Authors Alves, Katia, Plested, Joyce S., Galbiati, Shirley, Chau, Gordon, Cloney-Clark, Shane, Zhu, Mingzhu, Kalkeri, Raj, Patel, Nita, Smith, Kathy, Marcheschi, Alex, Pfeiffer, Susan, McFall, Heather, Smith, Gale, Glenn, Gregory M., Dubovsky, Filip, Mallory, Raburn M.
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 02.03.2023
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Abstract Boosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody specific for the ancestral strain and omicron variants. Whether the elicited antibodies protect against infection is unclear.
AbstractList Boosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody specific for the ancestral strain and omicron variants. Whether the elicited antibodies protect against infection is unclear.
Fourth Dose of SARS-CoV-2 Adjuvanted Protein VaccineBoosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody specific for the ancestral strain and omicron variants. Whether the elicited antibodies protect against infection is unclear.
Author Patel, Nita
Smith, Kathy
Marcheschi, Alex
Glenn, Gregory M.
Smith, Gale
Dubovsky, Filip
McFall, Heather
Kalkeri, Raj
Chau, Gordon
Plested, Joyce S.
Cloney-Clark, Shane
Zhu, Mingzhu
Pfeiffer, Susan
Alves, Katia
Galbiati, Shirley
Mallory, Raburn M.
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CitedBy_id crossref_primary_10_1038_s41541_024_00806_2
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Cites_doi 10.1038/s41598-021-03154-6
10.1101/2022.01.03.21268582
10.1016/S1473-3099(22)00420-0
10.1056/NEJMc1803554
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Mallory, RM, Formica, N, Pfeiffer, S (r1) 2022; 22
Huang, Y, Borisov, O, Kee, JJ (r2) 2021; 11
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  article-title: Safety and immunogenicity following a homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine (NVX-CoV2373): a secondary analysis of a randomised, placebo-controlled, phase 2 trial.
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Snippet Boosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody specific for the ancestral strain and omicron variants....
Fourth Dose of SARS-CoV-2 Adjuvanted Protein VaccineBoosters of adjuvanted NVX-CoV2373 protein vaccine led to increasing neutralizing titers of antibody...
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SubjectTerms Cartography
Coronavirus
Coronaviruses
Correspondence
COVID-19 Vaccines - administration & dosage
COVID-19 Vaccines - immunology
Disease transmission
Humans
Immunogenicity
Immunogenicity, Vaccine - immunology
Infectious Disease
Proteins
Severe acute respiratory syndrome coronavirus 2
Software
Vaccines
Viral Infections
SubjectTermsDisplay Coronavirus
Infectious Disease
Vaccines
Viral Infections
Title Immunogenicity of a Fourth Homologous Dose of NVX-CoV2373
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