Formulation of liposomes functionalized with Lotus lectin and effective in targeting highly proliferative cells - Della Giovampaola, Cinzia; Capone, Antonietta; Ermini, Leonardo; Lupetti, Pietro; Vannuccini, Elisa; Finetti, Federica; Donnini, Sandra; Ziche, Marina; Magnani, Agnese; Leone, Gemma; Rossi, Claudio; Rosati, Floriana; et al. (Biochimica et biophysica acta. General subjects, 2017)
Keywords: Animals; Binding Sites; Cell Line, Tumor; Cell Proliferation - drug effects; Chemistry, Pharmaceutical - methods; confocal laser scanning microscopy; Cytoplasm - drug effects; Doxorubicin; Doxorubicin - administration & dosage; Doxorubicin - chemistry; Drug delivery; Drug Delivery Systems - methods; drug therapy; Epitopes - administration & dosage; Epitopes - chemistry; Fabaceae - metabolism; fucose; Humans; lectins; Lectins - administration & dosage; Lectins - chemistry; Liposomes - administration & dosage; Liposomes - chemistry; Lotus lectin; Lotus tetragonolobus; lysosomes; Lysosomes - drug effects; melanoma; Melanoma, Experimental - drug therapy; Mice; NMR; polysaccharides; Targeted liposomes; DOPE; LTL; LTL-Dex-L; LTL-Dox-L; Drug delivery; Targeted liposomes; Dox; L; Lotus lectin; Doxorubicin; NMR; LTL-L; Dex; Dex-L; DOPC; Dox-L