Quantitative mapping of individual voxels in the peritumoral region of IDH-wildtype glioblastoma to distinguish between tumor infiltration and edema

• Published in: Journal of neuro-oncology Vol. 153; no. 2; pp. 251 - 261
• Main Authors: Dasgupta, Archya, Geraghty, Benjamin, Maralani, Pejman Jabehdar, Malik, Nauman, Sandhu, Michael, Detsky, Jay, Tseng, Chia-Lin, Soliman, Hany, Myrehaug, Sten, Husain, Zain, Perry, James, Lau, Angus, Sahgal, Arjun, Czarnota, Gregory J.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2021; Springer Nature B.V
• Subjects: Brain cancer; Brain tumors; Clinical Study; Diffusion coefficient; Edema; Glioblastoma; Glioma; Magnetic resonance imaging; Medicine; Medicine & Public Health; Metastases; Neuroimaging; Neurology; Oncology; Radiomics; Magnetic resonance imaging (MRI); Edema; Peritumoral region; Glioblastoma multiforme (GBM); Radiomics

Purpose The peritumoral region (PTR) in glioblastoma (GBM) represents a combination of infiltrative tumor and vasogenic edema, which are indistinguishable on magnetic resonance imaging (MRI). We developed a radiomic signature by using imaging data from low grade glioma (LGG) (marker of tumor) and PT...