Rab3a attenuates spinal cord injury by mediating vesicle release

• Published in: Brain research bulletin Vol. 208; p. 110884
• Main Authors: Yang, Yuhao, Liu, Ziqiao, Lu, Yang, Yu, Xincheng, Zhu, Rui, Cai, Xingda, Lin, Jinghua, Wang, Zemin, Zha, Dingsheng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2024; Elsevier
• Subjects: Extracellular vesicles; Macrophage polarization; Rab3a; Spinal cord injury; STXBP1; Rab3a; Extracellular vesicles; Macrophage polarization; Spinal cord injury; STXBP1

Rab3a regulates vesicle secretion and transport. Emerging evidences have shown that extracellular vesicles (EVs) can reach target lesions of injured spinal cords and exert a positive effect on these lesions. However, the molecular mechanism by which Rab3a regulates vesicle secretion to ameliorate sp...