Is Complete Pathologic Response in Pancreatic Cancer Overestimated? A Systematic Review of Prospective Studies

• Published in: Journal of gastrointestinal surgery Vol. 24; no. 10; pp. 2336 - 2348
• Main Authors: Laura, Antolino, Anna, Crovetto, Cinquepalmi, Matteo, Giovanni, Moschetta, Sole, Mattei Maria, Nava, Andrea Kazemi, Niccolò, Petrucciani, Giuseppe, Nigri, Stefano, Valabrega, Paolo, Aurello, Francesco, D’Angelo, Giovanni, Ramacciato
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2020; Springer Nature B.V
• Subjects: Cancer therapies; Classification; English language; Gastroenterology; Humans; Medicine; Medicine & Public Health; Metastasis; Neoadjuvant Therapy; Pancreatic cancer; Pancreatic Neoplasms - therapy; Prospective Studies; Radiation therapy; Retrospective Studies; Review Article; Software; Surgery; Survival analysis; Systematic review; Tumors; Neoadjuvant; Complete pathologic response; Pancreatic surgery; Pancreatic cancer

Background In literature, percentages of pathologic complete response (pCR) in patients presenting with resectable (RES), borderline resectable (BLR) or locally advanced (LA) pancreatic cancer (PaC) after neoadjuvant treatment (NADT) are variable, ranging 0–33%. Those data come mostly from retrospec...