Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats - Zhu, Yulin; Li, Shihong; Liu, Jingying; Wen, Qing; Yu, Jingui; Yu, Lingzhi; Xie, Kun (Inflammation, 2019)
Keywords: Animals; Apoptosis; Autophagy; Autophagy - drug effects; Biomedical and Life Sciences; Biomedicine; Brain Injuries; Brain injury; c-Jun protein; Caspase; Caspase-3; Cerebral blood flow; Cerebral infarction; Dexmedetomidine - pharmacology; Dexmedetomidine - therapeutic use; Enzyme-linked immunosorbent assay; Gene expression; Immunology; Infarction, Middle Cerebral Artery; Inflammation; Inflammation - prevention & control; Internal Medicine; Ischemia; JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases - metabolism; JNK protein; Kinases; Latency; Learning Disabilities - drug therapy; MAP Kinase Signaling System - physiology; Memory Disorders - drug therapy; mRNA; Original Article; Pathology; Phagocytosis; Pharmacology/Toxicology; Phosphorylation; Rats; Reperfusion; Reperfusion Injury - drug therapy; Rheumatology; Signal transduction; Spatial discrimination learning; Spatial memory; Transcription factors; Transmission electron microscopy; JNK signaling pathway; Inflammation; Ischemia reperfusion injury; Autophagy; Dexmedetomidine