In vitro α-glucosidase inhibitory activity of Tamarix nilotica shoot extracts and fractions

• Published in: PloS one Vol. 17; no. 3; p. e0264969
• Main Authors: Daou, Mariane, Elnaker, Nancy A, Ochsenkühn, Michael A, Amin, Shady A, Yousef, Ahmed F, Yousef, Lina F
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.03.2022; Public Library of Science (PLoS)
• Subjects: Acarbose; alpha-Glucosidases - metabolism; Anticoagulants; Antidiabetics; Antifungal agents; Biology; Biology and Life Sciences; Cardiovascular disease; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2; Diabetic retinopathy; Drugs; Enzymes; Ethanol; Fatty acids; Flavone glycosides; Flavonoids; Flavonoids - pharmacology; Glucose; Glucosidase; Glycoside Hydrolase Inhibitors - chemistry; Glycoside Hydrolase Inhibitors - pharmacology; Glycosides; Hyperglycemia; Inhibitors; Insulin resistance; Kinetics; Medicine and Health Sciences; Metabolites; Metabolomics; Methanol; Physical Sciences; Phytochemicals; Plant extracts; Plant Extracts - chemistry; Plant Extracts - pharmacology; Statistical analysis; Tamaricaceae - metabolism; Tamarix; Terpenes; Triterpenoids; α-Glucosidase; New York; United Arab Emirates; United States > US; Abu Dhabi United Arab Emirates

α-glucosidase inhibitors represent an important class of type 2 antidiabetic drugs and they act by lowering postprandial hyperglycemia. Today, only three synthetic inhibitors exist on the market, and there is a need for novel, natural and more efficient molecules exhibiting this activity. In this st...