Image‐based reconstruction of three‐dimensional myocardial infarct geometry for patient‐specific modeling of cardiac electrophysiology

• Published in: Medical physics (Lancaster) Vol. 42; no. 8; pp. 4579 - 4590
• Main Authors: Ukwatta, Eranga, Arevalo, Hermenegild, Rajchl, Martin, White, James, Pashakhanloo, Farhad, Prakosa, Adityo, Herzka, Daniel A., McVeigh, Elliot, Lardo, Albert C., Trayanova, Natalia A., Vadakkumpadan, Fijoy
• Format: Journal Article
• Language: English
• Published: United States American Association of Physicists in Medicine 01.08.2015
• Subjects: 60 APPLIED LIFE SCIENCES; Animals; Biological material, e.g. blood, urine; Haemocytometers; biomedical MRI; BIOMEDICAL RADIOGRAPHY; Contrast Media; CORONARIES; Digital computing or data processing equipment or methods, specially adapted for specific applications; DOGS; electrocardiography; Electrocardiography, i.e. ecg; Electrodynamics in the nervous system; ELECTROPHYSIOLOGY; GADOLINIUM; HEART; Humans; Image data processing or generation, in general; image reconstruction; image resolution; image‐based reconstruction; Imaging, Three-Dimensional - methods; interpolation; Involving electronic [emr] or nuclear [nmr] magnetic resonance, e.g. magnetic resonance imaging; ISCHEMIA; logarithm of odds; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Magnetic Resonance Physics; Medical image artifacts; medical image processing; Medical image reconstruction; Medical image segmentation; MRI: anatomic, functional, spectral, diffusion; muscle; myocardial infarct; MYOCARDIAL INFARCTION; Myocardial Infarction - pathology; Myocardium - pathology; Neuroscience; NMR IMAGING; Patient-Specific Modeling; PATIENTS; physiological modeling; RADIATION PROTECTION AND DOSIMETRY; Reconstruction; SIMULATION; Spatial resolution; Surface reconstruction; Three dimensional image processing; Tissues

Purpose: Accurate three‐dimensional (3D) reconstruction of myocardial infarct geometry is crucial to patient‐specific modeling of the heart aimed at providing therapeutic guidance in ischemic cardiomyopathy. However, myocardial infarct imaging is clinically performed using two‐dimensional (2D) late‐...