Regulation of metabolic homeostasis by the TGF‐β superfamily receptor ALK7

• Published in: The FEBS journal Vol. 289; no. 19; pp. 5776 - 5797
• Main Author: Ibáñez, Carlos F.
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell Publishing Ltd 01.10.2022
• Subjects: Activin; adipocyte; Adipocytes; Arcuate nucleus; beta‐cell; Cerebellum; diabetes; energy; genes; Homeostasis; humans; Hypothalamus; insulin; Kinases; lipolysis; Metabolic disorders; Metabolic syndrome; Metabolism; mice; NPY; obesity; pancreas; Pituitary; Receptor mechanisms; Receptors; reproduction; Therapeutic applications; therapeutics; Transforming growth factor-b

ALK7 (Activin receptor‐like kinase 7) is a member of the TGF‐β receptor superfamily predominantly expressed by cells and tissues involved in endocrine functions, such as neurons of the hypothalamus and pituitary, pancreatic β‐cells and adipocytes. Recent studies have begun to delineate the processes...