Structure-Expression Relationship of Tumor Necrosis Factor Receptor Mutants That Increase Expression
The extracellular domain of the p55 TNF receptor (TNFrED) is an important therapeutic protein for targeting tumor necrosis factor-α (TNF-α). The expression level of the TNFrED is low for bioproduction, which is presumably associated with the complication of pairing 24 cysteine residues to form corre...
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Published in | The Journal of biological chemistry Vol. 278; no. 31; pp. 28961 - 28967 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.08.2003
American Society for Biochemistry and Molecular Biology |
Subjects | |
Online Access | Get full text |
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