Membrane-bound progesterone receptors in the canine uterus and placenta; possible targets in the maintenance of pregnancy

• Published in: Theriogenology Vol. 210; pp. 68 - 83
• Main Authors: Kazemian, Ali, Tavares Pereira, Miguel, Aslan, Selim, Payan-Carreira, Rita, Reichler, Iris M., Agaoglu, Reha A., Kowalewski, Mariusz P.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.10.2023
• Subjects: Decidualization; Dog (Canis lupus familiaris); Membrane-bound P4 receptors; Placenta; Placenta; Dog (Canis lupus familiaris); Decidualization; Membrane-bound P4 receptors

To date, the biological functions of P4 within the canine placenta have been attributed to maternal stroma-derived decidual cells as the only placental cells expressing the nuclear P4 receptor (PGR). However, P4 can also exert its effects via membrane-bound receptors. To test the hypothesis that mem...