Human pituitary contains dual cathepsin L and prohormone convertase processing pathway components involved in converting POMC into the peptide hormones ACTH, α-MSH, and β-endorphin
The production of the peptide hormones ACTH, α-MSH, and β-endorphin requires proteolytic processing of POMC which is hypothesized to utilize dual cysteine- and subtilisin-like protease pathways, consisting of the secretory vesicle cathepsin L pathway and the well-known subtilisin-like prohormone con...
Saved in:
Published in | Endocrine Vol. 35; no. 3; pp. 429 - 437 |
---|---|
Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Boston
Springer US
01.06.2009
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!