Influence of obese phenotype on metabolic profile, inflammatory mediators and stemness of hADSC in adipose tissue

• Published in: Clinical nutrition (Edinburgh, Scotland) Vol. 39; no. 12; pp. 3829 - 3835
• Main Authors: Rawal, Komal, Patel, Tushar P., Purohit, Kishan M., Israni, Kashish, Kataria, Vyakhaya, Bhatt, Hiren, Gupta, Sarita
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2020
• Subjects: adipogenesis; adiponectin; adipose tissue; body mass index; bone formation; developing countries; diabetes; Differentiation; eating habits; exercise; genes; growth models; hADSC; India; inflammation; insulin; insulin resistance; Insulin signaling; leptin; metabolic syndrome; Metabolically obese Indian; MYF-5; obesity; phenotype; resistin; sedentary lifestyle; stem cells; therapeutics; transcription factors; Whites; India; Metabolically obese Indian; hADSC; MYF-5; Differentiation; Insulin signaling

Unhealthy dietary practices, sedentary life style and lack of physical exercise in developing countries like India are major contributors of metabolic syndrome like obesity and diabetes. Obesity in Indians is defined at Body Mass Index (BMI, kg/m2) >25 and characterized as metabolically obese. A...