EORTC Melanoma Group sentinel node protocol identifies high rate of submicrometastases according to Rotterdam Criteria

• Published in: European journal of cancer (1990) Vol. 46; no. 13; pp. 2414 - 2421
• Main Authors: van der Ploeg, Augustinus P.T, van Akkooi, Alexander C.J, Schmitz, Paul I.M, Koljenovic, Senada, Verhoef, Cornelis, Eggermont, Alexander M.M
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.09.2010; Elsevier
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Disease-Free Survival; Female; Hematology, Oncology and Palliative Medicine; Humans; Lymph Node Excision - methods; Lymph Node Excision - mortality; Lymphatic Metastasis; Male; Medical sciences; Melanoma; Melanoma - pathology; Melanoma - secondary; Melanoma - surgery; Middle Aged; Multivariate analysis; Pharmacology. Drug treatments; Prognosis; Prognostic factors; Retrospective Studies; Sentinel Lymph Node Biopsy - methods; Sentinel node; Skin Neoplasms - pathology; Skin Neoplasms - surgery; Tumors; Young Adult; Sentinel node; Multivariate analysis; Prognostic factors; Melanoma; Cancerology; Prognosis; Malignant melanoma; Malignant tumor; Cancer; European Organization for Research and Treatment of Cancer

Abstract Sentinel node (SN) status is the most important prognostic factor for disease-free survival (DFS) and overall survival (OS) in stages I–II melanoma. We evaluated the positive sentinel node identification rate of the EORTC Melanoma Group (MG) protocol as well as its capacity to identify mini...